The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Hormone-Sensitive Lipase: Sequence, Expression, and Chromosomal Localization to 19 cent-q13.3
Abstract
Hormone-sensitive lipase, a key enzyme in fatty acid mobilization, overall energy homeostasis, and possibly steroidogenesis, is acutely controlled through reversible phosphorylation by catecholamines and insulin. The 757-amino acid sequence predicted from a cloned rat adipocyte complementary DNA showed no homology with any other known lipase or protein. The activity-controlling phosphorylation site was localized to Ser 563 in a markedly hydrophilic domain, and a lipid-binding consensus site was tentatively identified. One or several messenger RNA species (3.3, 3.5, or 3.9 kilobases) were expressed in adipose and steroidogenic tissues and heart and skeletal muscle. The human hormone-sensitive lipase gene mapped to chromosome 19 cent-q13.3.
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Advancing diagnosis and management of liver disease in adults through exome sequencing
Zheng, M., Hakim, A., Konkwo, C., Deaton, A. M., Ward, L. D., Silveira, M. G., Assis, D. N., Liapakis, A., Jaffe, A., Jiang, Z. G., et al. (2023) · EBioMedicine · doi:10.1016/j.ebiom.2023.104747 · Cited by 34
Metadata
- Authors
- Holm, C., Kirchgessner, T. G., Svenson, K. L., Fredrikson, G., Nilsson, S., Miller, C. G., Shively, J. E., Heinzmann, C., Sparkes, R. S., Mohandas, T., Lusis, A. J., Belfrage, P., & Schotz, M. C.
- Venue
- Science
- Published
- 1988-09-16
- Volume
- 241
- Issue
- 4872
- Pages
- 1503-1506
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2023996613
- Cited by
- 307
- References
- 1
- FWCI
- 12.23
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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