The DOI matches its Crossref record.
Imaging of phosphorescence: a novel method for measuring oxygen distribution in perfused tissue
Abstract
The imaging of phosphorescence provides a method for monitoring oxygen distribution within the vascular system of intact tissues. Isolated rat lives were perfused through the portal vein with media containing palladium coproporphyrin, which phosphoresced and was used to image the liver at various perfusion rates. Because oxygen is a powerful quenching agent for phosphors, the transition from well-perfused liver to anoxia (no flow of oxygen) resulted in large increases of phosphorescence. During stepwise restoration of oxygen flow, the phosphorescence images showed marked heterogeneous patterns of tissue reoxygenation, which indicated that there were regional inequalities in oxygen delivery.
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Research works printed but not linked: 8
- CAMPRA, J.C., LIVER BIOL PATHOBIOL 632 (1982).
- 10.1002/jcp.1041330115 · doi:10.1002/jcp.1041330115
- MATSUMURA, T, O-2 UPTAKE IN PERIPORTAL AND PERICENTRAL REGIONS OF LIVER LOBULE IN PERFUSED LIVER, AMERICAN JOURNAL OF PHYSIOLOGY 250: G800 (1986).
- VANDERKOOI, J.M., ADV EXP MED BIOL 200: 189 (1987).
- 10.1016/S0021-9258(18)45596-2 · DOI · Paper page
- 10.1007/978-1-4684-7433-6_9 · doi:10.1007/978-1-4684-7433-6_9
- WILSON, D.F., ADV EXP MED BIOL 220: 121 (1988).
- 10.1016/S0021-9258(18)69126-4 · DOI · Paper page
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Walsh, J. C., Lebedev, A., Aten, E., Madsen, K., Marciano, L., & Kolb, H. C. (2014) · Antioxidants & Redox Signaling · doi:10.1089/ars.2013.5378 · Cited by 420
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Metadata
- Authors
- Rumsey, W., Vanderkooi, J., & Wilson, D.
- Venue
- Science
- Published
- 1988-09-23
- Volume
- 241
- Issue
- 4873
- Pages
- 1649-1651
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2094866017
- Cited by
- 534
- References
- 0
- FWCI
- 4.28
- Type
- journal article
- Language
- en
- Open access
- closed
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- Rumsey, W., Vanderkooi, J., & Wilson, D. (1988). Imaging of phosphorescence: a novel method for measuring oxygen distribution in perfused tissue. Science. https://doi.org/10.1126/science.241.4873.1649
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