The DOI matches its Crossref record; 15 of the 15 references it cites were found in a registry or an index.
Expression of an Exogenous Growth Hormone Gene by Transplantable Human Epidermal Cells
Abstract
Retrovirus-mediated gene transfer was used to introduce a recombinant human growth hormone gene into cultured human keratinocytes. The transduced keratinocytes secreted biologically active growth hormone into the culture medium. When grafted as an epithelial sheet onto athymic mice, these cultured keratinocytes reconstituted an epidermis that was similar in appearance to that resulting from normal cells, but from which human growth hormone could be extracted. Transduced epidermal cells may prove to be a general vehicle for the delivery of gene products by means of grafting.
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Cites
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Self-citationPermanent Coverage of Large Burn Wounds with Autologous Cultured Human Epithelium
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Self-citationDe novo methylation and expression of retroviral genomes during mouse embryogenesis
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Cited by
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The Basic Science of Gene Therapy
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Self-citationRepair of demyelinated lesions by transplantation of purified 0-2A progenitor cells
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In vivo electroporation and stable transformation of skin cells of newborn mice by plasmid DNA
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Systemic Delivery of Human Growth Hormone by Injection of Genetically Engineered Myoblasts
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Metadata
- Authors
- Morgan, J. R., Barrandon, Y., Green, H., & Mulligan, R. C.
- Venue
- Science
- Published
- 1987-09-18
- Volume
- 237
- Issue
- 4821
- Pages
- 1476-1479
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W1977492095
- Cited by
- 272
- References
- 15
- FWCI
- 9.69
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Expression of an Exogenous Growth Hormone Gene by Transplantable Human Epidermal Cells. https://app.cochat.ai/papers/10.1126/science.3629250
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- Morgan, J. R., Barrandon, Y., Green, H., & Mulligan, R. C. (1987). Expression of an Exogenous Growth Hormone Gene by Transplantable Human Epidermal Cells. Science. https://doi.org/10.1126/science.3629250
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.