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Growth of cultured human epidermal cells into multiple epithelia suitable for grafting.
Open accessAbstract
Owing to several recent developments, the cultivability of epidermal keratinocytes, particularly those of the human, has been greatly improved. Under the conditions used, single cultured cells generate stratified colonies that ultimately fuse and form an epithelium that is reasonable approximation of the epidermis. It will be shown here that large amounts of cultured epithelium can be generated from a small piece of epidermis in a short time. We wish to bring to the attention of surgeons and cell biologists the possibility of using culture-grown epithelium derived from the same individual to restore defects in the epidermis.
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Cited by
Regulation of terminal differentiation of cultured human keratinocytes by vitamin A
Fuchs, E., & Green, H. (1981) · Cell · doi:10.1016/0092-8674(81)90169-0 · Cited by 750
Self-citationTissue Engineering and Regenerative Medicine: History, Progress, and Challenges
Berthiaume, F., Maguire, T. J., & Yarmush, M. L. (2011) · Annual Review of Chemical and Biomolecular Engineering · doi:10.1146/annurev-chembioeng-061010-114257 · Cited by 734
Pellegrini, G., Golisano, O., Paterna, P., Lambiase, A., Bonini, S., Rama, P., & De Luca, M. (1999) · The Journal of Cell Biology · doi:10.1083/jcb.145.4.769 · Cited by 722
Three-dimensional organotypic culture: experimental models of mammalian biology and disease
Shamir, E. R., & Ewald, A. J. (2014) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm3873 · Cited by 719
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Babensee, J. E., Anderson, J. M., McIntire, L. V., & Mikos, A. G. (1998) · Advanced Drug Delivery Reviews · doi:10.1016/s0169-409x(98)00023-4 · Cited by 585
Metadata
- Authors
- Green, H., Kehinde, O., & Thomas, J.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 1979-11
- Volume
- 76
- Issue
- 11
- Pages
- 5665-5668
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W2042629233
- Cited by
- 1,250
- References
- 0
- FWCI
- 2.14
- Type
- journal article
- Language
- en
- Open access
- green
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- Green, H., Kehinde, O., & Thomas, J. (1979). Growth of cultured human epidermal cells into multiple epithelia suitable for grafting. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.76.11.5665
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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