The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Cigarette Craving, Smoking Withdrawal, and Clonidine
Abstract
Clonidine, an α-2-adrenergic agonist, significantly reduces opiate withdrawal. Fifteen heavy smokers abstained from cigarettes on three separate occasions and received instead clonidine, placebo, or the benzodiazepine alprazolam. Clonidine and alprazolam diminished withdrawal symptoms. The two drugs suppressed anxiety, tension, irritability, and restlessness equally but clonidine had a greater effect than alprazolam on cigarette craving. These observations suggest that noradrenergic activity is a common feature in the pathophysiology of withdrawal and that a special relationship exists between central noradrenergic activity and craving.
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Cites
Foote, S. L., Aston-Jones, G., & Bloom, F. E. (1980) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.77.5.3033 · Cited by 857
Korf, J., Aghajanian, G. K., & Roth, R. H. (1973) · Neuropharmacology · doi:10.1016/0028-3908(73)90024-5 · Cited by 311
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A cognitive model of drug urges and drug-use behavior: role of automatic and nonautomatic processes
Tiffany, S. T. (1990) · Psychological Review · doi:10.1037/0033-295x.97.2.147 · Cited by 1,554
Cox, L. S., Tiffany, S. T., & Christen, A. G. (2001) · Nicotine & Tobacco Research · doi:10.1080/14622200020032051 · Cited by 1,188
The development and initial validation of a questionnaire on smoking urges
TIFFANY, S. T., & DROBES, D. J. (1991) · British Journal of Addiction · doi:10.1111/j.1360-0443.1991.tb01732.x · Cited by 974
Alpha‐2 and imidazoline receptor agonistsTheir pharmacology and therapeutic role
Khan, Z. P., Ferguson, C. N., & Jones, R. M. (1999) · Anaesthesia · doi:10.1046/j.1365-2044.1999.00659.x · Cited by 686
Metadata
- Authors
- Glassman, A. H., Jackson, W. K., Walsh, B. T., Roose, S. P., & Rosenfeld, B.
- Venue
- Science
- Published
- 1984-11-16
- Volume
- 226
- Issue
- 4676
- Pages
- 864-866
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2051140578
- Cited by
- 206
- References
- 2
- FWCI
- 12.29
- Type
- journal article
- Language
- en
- Open access
- closed
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- Glassman, A. H., Jackson, W. K., Walsh, B. T., Roose, S. P., & Rosenfeld, B. (1984). Cigarette Craving, Smoking Withdrawal, and Clonidine. Science. https://doi.org/10.1126/science.6387913
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
