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Cited by 287

The DOI matches its Crossref record; 55 of the 55 references it cites were found in a registry or an index.

Endocytosis: Relation to Capping and Cell Locomotion

Bretscher, Mark S.·1984·Science

Abstract

Most mammalian cells, such as fibroblasts, continuously internalize part of their surface membrane by endocytosis, and then later return it to the cell surface. This cyclical process is initiated by coated pits in the plasma membrane. These pits collect specific receptors plus lipid for internalization, but exclude other proteins. On a motile cell, the sites of endocytosis (randomly located on the cell) and those of membrane return (located at the front of the cell) are not coincident. This causes a bulk flow of lipid plus receptors in the plasma membrane, away from the front of the cell. Large objects on the cell surface are swept to the rear of the cell by this flow, a process called capping. Cells may use this polarized endocytic cycle to move.

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Metadata

Authors
Bretscher, M. S.
Venue
Science
Published
1984-05-18
Volume
224
Issue
4650
Pages
681-686
ISSN
  • 0036-8075 (ISSN-L)
  • 1095-9203
OpenAlex
W2053550995
Cited by
287
References
55
FWCI
10.81
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Endocytosis: Relation to Capping and Cell Locomotion. https://app.cochat.ai/papers/10.1126/science.6719108
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Bretscher, M. S. (1984). Endocytosis: Relation to Capping and Cell Locomotion. Science. https://doi.org/10.1126/science.6719108

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.