The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Antigen-Specific Development of Primary and Memory T Cells in Vivo
Abstract
The expansion and contraction of specific helper T cells in the draining lymph nodes of normal mice after injection with antigen was followed. T cell receptors from purified primary and memory responder cells had highly restricted junctional regions, indicating antigen-driven selection. Selection for homogeneity in the length of the third complementarity-determining region (CDR3) occurs before selection for some of the characteristic amino acids, indicating the importance of this parameter in T cell receptor recognition. Ultimately, particular T cell receptor sequences come to predominate in the secondary response and others disappear, showing the selective preservation or expansion of specific T cell clones.
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Citations
Cites
Turnover of naive- and memory-phenotype T cells.
Tough, D. F., & Sprent, J. (1994) · The Journal of experimental medicine · doi:10.1084/jem.179.4.1127 · Cited by 869
Vitetta, E. S., Berton, M. T., Burger, C., Kepron, M., Lee, W. T., & Yin, X. M. (1991) · Annual Review of Immunology · doi:10.1146/annurev.iy.09.040191.001205 · Cited by 187
Cited by
Phenotypic Analysis of Antigen-Specific T Lymphocytes
Altman, J. D., Moss, P. A. H., Goulder, P. J. R., Barouch, D. H., McHeyzer-Williams, M. G., Bell, J. I., McMichael, A. J., & Davis, M. M. (1996) · Science · doi:10.1126/science.274.5284.94 · Cited by 3,544
Self-citationImmunological memory and protective immunity: understanding their relation
Ahmed, R., & Gray, D. (1996) · Science · doi:10.1126/science.272.5258.54 · Cited by 1,775
Visualizing the generation of memory CD4 T cells in the whole body
Reinhardt, R. L., Khoruts, A., Merica, R., Zell, T., & Jenkins, M. K. (2001) · Nature · doi:10.1038/35065111 · Cited by 1,026
Callan, M. F. C., Tan, L., Annels, N., Ogg, G. S., Wilson, J. D. K., O'Callaghan, C. A., Steven, N., McMichael, A. J., & Rickinson, A. B. (1998) · The Journal of Experimental Medicine · doi:10.1084/jem.187.9.1395 · Cited by 892
Dutton, R. W., Bradley, L. M., & Swain, S. L. (1998) · Annual Review of Immunology · doi:10.1146/annurev.immunol.16.1.201 · Cited by 832
Metadata
- Authors
- McHeyzer-Williams, M. G., & Davis, M. M.
- Venue
- Science
- Published
- 1995-04-07
- Volume
- 268
- Issue
- 5207
- Pages
- 106-111
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2010436799
- Cited by
- 435
- References
- 2
- FWCI
- 15.52
- Type
- journal article
- Language
- en
- Open access
- closed
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- McHeyzer-Williams, M. G., & Davis, M. M. (1995). Antigen-Specific Development of Primary and Memory T Cells in Vivo. Science. https://doi.org/10.1126/science.7535476
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
