The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Activation of Yeast PBS2 MAPKK by MAPKKKs or by Binding of an SH3-Containing Osmosensor
Abstract
The role of mitogen-activated protein (MAP) kinase cascades in integrating distinct upstream signals was studied in yeast. Mutants that were not able to activate PBS2 MAP kinase kinase (MAPKK; Pbs2p) at high osmolarity were characterized. Pbs2p was activated by two independent signals that emanated from distinct cell-surface osmosensors. Pbs2p was activated by MAP kinase kinase kinases (MAPKKKs) Ssk2p and Ssk22p that are under the control of the SLN1-SSK1 two-component osmosensor. Alternatively, Pbs2p was activated by a mechanism that involves the binding of its amino terminal proline-rich motif to the Src homology 3 (SH3) domain of a putative transmembrane osmosensor Sho1p.
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Cites
Protein modules and signalling networks
Pawson, T. (1995) · Nature · doi:10.1038/373573a0 · Cited by 2,420
Independent Human MAP-Kinase Signal Transduction Pathways Defined by MEK and MKK Isoforms
Dérijard, B., Raingeaud, J., Barrett, T., Wu, I.-H., Han, J., Ulevitch, R. J., & Davis, R. J. (1995) · Science · doi:10.1126/science.7839144 · Cited by 1,555
Cited by
Mitogen-activated protein kinase cascades and regulation of gene expression
Su, B., & Karin, M. (1996) · Current Opinion in Immunology · doi:10.1016/s0952-7915(96)80131-2 · Cited by 747
The commercial production of chemicals using pathway engineering
Chotani, G., Dodge, T., Hsu, A., Kumar, M., LaDuca, R., Trimbur, D., Weyler, W., & Sanford, K. (2000) · Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology · doi:10.1016/s0167-4838(00)00234-x · Cited by 234
Comparative genomics of the environmental stress response in ascomycete fungi
Gasch, A. P. (2007) · Yeast · doi:10.1002/yea.1512 · Cited by 210
Bermejo, C., Rodríguez, E., García, R., Rodríguez-Peña, J. M., Rodríguez de la Concepción, M. L., Rivas, C., Arias, P., Nombela, C., Posas, F., & Arroyo, J. (2008) · Molecular Biology of the Cell · doi:10.1091/mbc.e07-08-0742 · Cited by 204
Distinct Signaling Pathways Mediate Touch and Osmosensory Responses in a Polymodal Sensory Neuron
Hart, A. C., Kass, J., Shapiro, J. E., & Kaplan, J. M. (1999) · The Journal of Neuroscience · doi:10.1523/jneurosci.19-06-01952.1999 · Cited by 175
Metadata
- Authors
- Maeda, T., Takekawa, M., & Saito, H.
- Venue
- Science
- Published
- 1995-07-28
- Volume
- 269
- Issue
- 5223
- Pages
- 554-558
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W1971453983
- Cited by
- 640
- References
- 2
- FWCI
- 15.99
- Type
- journal article
- Language
- en
- Open access
- closed
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- Maeda, T., Takekawa, M., & Saito, H. (1995). Activation of Yeast PBS2 MAPKK by MAPKKKs or by Binding of an SH3-Containing Osmosensor. Science. https://doi.org/10.1126/science.7624781
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