Candidate gene for the chromosome 1 familial Alzheimer’s disease locus

Levy-Lahad, Ephrat, Wasco, Wilma, Poorkaj, Parvoneh, Romano, Donna M., Oshima, Junko, Pettingell, Warren H., Yu, Chang-en, Jondro, Paul D., Schmidt, Stephen D., Wang, Kai, Crowley, Annette C., Fu, Ying-Hui, Guenette, Suzanne Y., Galas, David, Nemens, Ellen, Wijsman, Ellen M., Bird, Thomas D., Schellenberg, Gerard D., Tanzi, Rudolph E.·1995·Science
DOI 10.1126/science.7638622

Cited by (1,015)

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  2. Mechanisms of AD neurodegeneration may be independent of Aβ and its derivatives
    Nikolaos K. R K Robakis · 2010 · Neurobiology of Aging
  3. A Brief History of Alzheimer's Disease Gene Discovery
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  4. Regulation of Transcription of the Human Presenilin-1 Gene by Ets Transcription Factors and the p53 Protooncogene
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  5. Handbook of the neuroscience of aging
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  6. Familial Aggregation of Dyslexia Phenotypes
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  7. Presenilin 1 Protein Directly Interacts with Bcl-2
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  11. Nitric oxide in the cerebral cortex of amyloid-precursor protein (SW) Tg2576 transgenic mice
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  13. New Insights into the Genetics of Alzheimer's Disease
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  14. The use of Seldi ProteinChip? Arrays to monitor production of Alzheimer's ?-amyloid in transfected cells
    Brian Austen, Emma R. Frears, Huw Davies · 2000 · Journal of Peptide Science
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  18. The Pathogenic Aβ43 Is Enriched in Familial and Sporadic Alzheimer Disease
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  19. Molecular genetics of Alzheimer’s disease
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  30. Review: David Oppenheimer Memorial Lecture 1995: Some neuropathological aspects of Alzheimer's disease and its relevance to other disciplines*
    Henryk M. Wı́sniewski, Jerzy Węgiel, Leszek Kotula · 1996 · Neuropathology and Applied Neurobiology
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    Charles R. Harrington · 2012 · Neuroimaging Clinics of North America
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    Anver Kuliev · 2012 · Springer eBooks
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    Dennis J. Selkoe · 2000 · Current Opinion in Neurobiology
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  49. Expression of mutant amyloid precursor proteins induces apoptosis in PC12 cells
    Boyu Zhao, Francis J. Chrest, Walter E. Horton, Sangram S. Sisodia, John W. Kusiak · 1997 · Journal of Neuroscience Research
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    Carlos A. Saura, Taisuke Tomita, Salvador Soriano, Masaaki Takahashi, Jae-Yoon Leem, Toshiyuki Honda, Edward H. Koo, Takeshi Iwatsubo, Gopal Thinakaran · 2000 · Journal of Biological Chemistry
  51. Relation of genomic variants for Alzheimer disease dementia to common neuropathologies
    Farfel, Jose M., Yu, Lei, Buchman, Aron S., Schneider, Julie A., De Jager, Philip L., Bennett, David A. · 2016 · Neurology
  52. Alzheimer diseases: a model of gene mutations and susceptibility polymorphisms for complex psychiatric diseases
    Allen D. Roses · 1998 · American Journal of Medical Genetics
  53. Amyloid and Alzheimer's Disease: Inside and Out
    Joshua H. K. Tam, Stephen Pasternak · 2012 · Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques
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    A. L. Schwarzman, Nandita Singh, Maria V. Tsiper, Luisa L. Gregori, Alex Dranovsky, Michael Peter Vitek, Charles G. Glabe, Peter St George‐Hyslop, Dmitry Goldgaber · 1999 · Proceedings of the National Academy of Sciences
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    Wolozin, B. · 2002 · Biochemical Society Transactions
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