The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
The Chromodomain Protein Swi6: A Key Component at Fission Yeast Centromeres
Abstract
Centromeres attach chromosomes to the spindle during mitosis, thereby ensuring the equal distribution of chromosomes into daughter cells. Transcriptionally silent heterochromatin of unknown function is associated with centromeres in many organisms. In the fission yeast Schizosaccharomyces pombe , the silent mating-type loci, centromeres, and telomeres are assembled into silent heterochromatin-like domains. The Swi6 chromodomain protein affects this silencing, and now it is shown that Swi6p localizes with these three chromosomal regions. In cells lacking Swi6p, centromeres lag on the spindle during anaphase and chromosomes are lost at high rates. Thus, Swi6p is located at fission yeast centromeres and is required for their proper function.
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Eissenberg, J. C., Morris, G. D., Reuter, G., & Hartnett, T. (1992) · Genetics · doi:10.1093/genetics/131.2.345 · Cited by 315
Cited by
Selective recognition of methylated lysine 9 on histone H3 by the HP1 chromo domain
Bannister, A. J., Zegerman, P., Partridge, J. F., Miska, E. A., Thomas, J. O., Allshire, R. C., & Kouzarides, T. (2001) · Nature · doi:10.1038/35065138 · Cited by 2,903
Self-citationRequirement of Heterochromatin for Cohesion at Centromeres
Bernard, P., Maure, J.-F., Partridge, J. F., Genier, S., Javerzat, J.-P., & Allshire, R. C. (2001) · Science · doi:10.1126/science.1064027 · Cited by 616
Self-citationHeterochromatin: Guardian of the Genome
Janssen, A., Colmenares, S. U., & Karpen, G. H. (2018) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev-cellbio-100617-062653 · Cited by 500
Taddei, A., Maison, C., Roche, D., & Almouzni, G. (2001) · Nature Cell Biology · doi:10.1038/35055010 · Cited by 361
Heterochromatin Dynamics in Mouse Cells
Murzina, N., Verreault, A., Laue, E., & Stillman, B. (1999) · Molecular Cell · doi:10.1016/s1097-2765(00)80204-x · Cited by 300
Metadata
- Authors
- Ekwall, K., Javerzat, J.-P., Lorentz, A., Schmidt, H., Cranston, G., & Allshire, R.
- Venue
- Science
- Published
- 1995-09-08
- Volume
- 269
- Issue
- 5229
- Pages
- 1429-1431
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2029301727
- Cited by
- 299
- References
- 1
- FWCI
- 4.03
- Type
- journal article
- Language
- en
- Open access
- closed
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- Ekwall, K., Javerzat, J.-P., Lorentz, A., Schmidt, H., Cranston, G., & Allshire, R. (1995). The Chromodomain Protein Swi6: A Key Component at Fission Yeast Centromeres. Science. https://doi.org/10.1126/science.7660126
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.