The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Developmental Regulation of Neural Response to FGF-1 and FGF-2 by Heparan Sulfate Proteoglycan
Abstract
Murine neural precursor cells and cell lines derived from them are stimulated by members of the heparin-binding fibroblast growth factor (FGF) family. The activity of FGF is regulated by heparan sulfate proteoglycans (HSPGs), and this interaction is an essential prerequisite for the binding of growth factor to the signal transducing receptors. Messenger RNA for FGF-2 was detectable in the neuroepithelium at embryonic day 9, and the HSPGs produced by these cells at this time preferentially bound FGF-2. However, at embryonic day 11, when messenger RNA for FGF-1 was first detectable, there was a switch in the binding specificity of the HSPG to FGF-1. Thus, a single species of HSPG undergoes a rapid, tightly controlled change in growth factor-binding specificity concomitant with the temporal expression of the FGFs.
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Yayon, A., Klagsbrun, M., Esko, J. D., Leder, P., & Ornitz, D. M. (1991) · Cell · doi:10.1016/0092-8674(91)90512-w · Cited by 2,440
Extracellular matrix regulation of growth factor and protease activity
Flaumenhaft, R., & Rifkin, D. B. (1991) · Current Opinion in Cell Biology · doi:10.1016/0955-0674(91)90055-4 · Cited by 130
Cited by
Functions of Cell Surface Heparan Sulfate Proteoglycans
Bernfield, M., Götte, M., Park, P. W., Reizes, O., Fitzgerald, M. L., Lincecum, J., & Zako, M. (1999) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.68.1.729 · Cited by 2,688
The extracellular matrix in development and morphogenesis: A dynamic view
Rozario, T., & DeSimone, D. W. (2010) · Developmental Biology · doi:10.1016/j.ydbio.2009.10.026 · Cited by 1,451
Proteoglycans in the Developing Brain: New Conceptual Insights for Old Proteins
Bandtlow, C. E., & Zimmermann, D. R. (2000) · Physiological Reviews · doi:10.1152/physrev.2000.80.4.1267 · Cited by 632
Neuronal defects and delayed wound healing in mice lacking fibroblast growth factor 2
Ortega, S., Ittmann, M., Tsang, S. H., Ehrlich, M., & Basilico, C. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.10.5672 · Cited by 593
Fibroblast Growth Factor Signaling during Early Vertebrate Development
Böttcher, R. T., & Niehrs, C. (2005) · Endocrine Reviews · doi:10.1210/er.2003-0040 · Cited by 540
Metadata
- Authors
- Nurcombe, V., Ford, M. D., Wildschut, J. A., & Bartlett, P. F.
- Venue
- Science
- Published
- 1993-04-02
- Volume
- 260
- Issue
- 5104
- Pages
- 103-106
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2007230427
- Cited by
- 423
- References
- 2
- FWCI
- 14.16
- Type
- journal article
- Language
- en
- Open access
- closed
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- Nurcombe, V., Ford, M. D., Wildschut, J. A., & Bartlett, P. F. (1993). Developmental Regulation of Neural Response to FGF-1 and FGF-2 by Heparan Sulfate Proteoglycan. Science. https://doi.org/10.1126/science.7682010
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