The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Requirement of MADS Domain Transcription Factor D-MEF2 for Muscle Formation in Drosophila
Abstract
Members of the myocyte enhancer binding factor-2 (MEF2) family of MADS (MCM1, agamous, deficiens, and serum response factor) box transcription factors are expressed in the skeletal, cardiac, and smooth muscle lineages of vertebrate and Drosophila embryos. These factors bind an adenine-thymidine-rich DNA sequence associated with muscle-specific genes. The function of MEF2 was determined by generating a loss-of-function of the single mef2 gene in Drosophila ( D-mef2 ). In loss-of-function embryos, somatic, cardiac, and visceral muscle cells did not differentiate, but myoblasts were normally specified and positioned. These results demonstrate that different muscle cell types share a common myogenic differentiation program controlled by MEF2.
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Citations
Cites
The MyoD family and myogenesis: Redundancy, networks, and thresholds
Weintraub, H. (1993) · Cell · doi:10.1016/0092-8674(93)90610-3 · Cited by 1,057
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MEF2: a central regulator of diverse developmental programs
Potthoff, M. J., & Olson, E. N. (2007) · Development · doi:10.1242/dev.008367 · Cited by 834
Self-citationCooperative activation of muscle gene expression by MEF2 and myogenic bHLH proteins
Molkentin, J. D., Black, B. L., Martin, J. F., & Olson, E. N. (1995) · Cell · doi:10.1016/0092-8674(95)90139-6 · Cited by 819
Self-citationMolecular Pathways Controlling Heart Development
Olson, E. N., & Srivastava, D. (1996) · Science · doi:10.1126/science.272.5262.671 · Cited by 478
Self-citationp38 Mitogen-activated Protein Kinase Pathway Promotes Skeletal Muscle Differentiation
Zetser, A., Gredinger, E., & Bengal, E. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.8.5193 · Cited by 461
Metadata
- Authors
- Lilly, B., Zhao, B., Ranganayakulu, G., Paterson, B. M., Schulz, R. A., & Olson, E. N.
- Venue
- Science
- Published
- 1995-02-03
- Volume
- 267
- Issue
- 5198
- Pages
- 688-693
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2078422108
- Cited by
- 491
- References
- 1
- FWCI
- 13.62
- Type
- journal article
- Language
- en
- Open access
- closed
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- Lilly, B., Zhao, B., Ranganayakulu, G., Paterson, B. M., Schulz, R. A., & Olson, E. N. (1995). Requirement of MADS Domain Transcription Factor D-MEF2 for Muscle Formation in Drosophila. Science. https://doi.org/10.1126/science.7839146
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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