The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
A Lymphotoxin-β-Specific Receptor
Abstract
Tumor necrosis factor (TNF) and lymphotoxin-α (LT-α) are members of a family of secreted and cell surface cytokines that participate in the regulation of immune and inflammatory responses. The cell surface form of LT-α is assembled during biosynthesis as a heteromeric complex with lymphotoxin-β (LT-β), a type II transmembrane protein that is another member of the TNF ligand family. Secreted LT-α is a homotrimer that binds to distinct TNF receptors of 60 and 80 kilodaltons; however, these receptors do not recognize the major cell surface LT-α-LT-β complex. A receptor specific for human LT-β was identified, which suggests that cell surface LT may have functions that are distinct from those of secreted LT-α.
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Pfeffer, K., Matsuyama, T., Kündig, T. M., Wakeham, A., Kishihara, K., Shahinian, A., Wiegmann, K., Ohashi, P. S., Krönke, M., & Mak, T. W. (1993) · Cell · doi:10.1016/0092-8674(93)90134-c · Cited by 1,677
Cited by
The Death Domain Kinase RIP Mediates the TNF-Induced NF-κB Signal
Kelliher, M. A., Grimm, S., Ishida, Y., Kuo, F., Stanger, B. Z., & Leder, P. (1998) · Immunity · doi:10.1016/s1074-7613(00)80535-x · Cited by 1,102
Characterization of tumor necrosis factor-deficient mice
Marino, M. W., Dunn, A., Grail, D., Inglese, M., Noguchi, Y., Richards, E., Jungbluth, A., Wada, H., Moore, M., Williamson, B., et al. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.15.8093 · Cited by 622
DEVELOPMENT AND MATURATION OF SECONDARY LYMPHOID TISSUES
Fu, Y.-X., & Chaplin, D. D. (1999) · Annual Review of Immunology · doi:10.1146/annurev.immunol.17.1.399 · Cited by 616
A primer on cytokines: sources, receptors, effects, and inducers
Curfs, J. H., Meis, J. F., & Hoogkamp-Korstanje, J. A. (1997) · Clinical Microbiology Reviews · doi:10.1128/cmr.10.4.742 · Cited by 317
Roschke, V., Sosnovtseva, S., Ward, C. D., Hong, J. S., Smith, R., Albert, V., Stohl, W., Baker, K. P., Ullrich, S., Nardelli, B., et al. (2002) · The Journal of Immunology · doi:10.4049/jimmunol.169.8.4314 · Cited by 259
Metadata
- Authors
- Crowe, P. D., VanArsdale, T. L., Walter, B. N., Ware, C. F., Hession, C., Ehrenfels, B., Browning, J. L., Din, W. S., Goodwin, R. G., & Smith, C. A.
- Venue
- Science
- Published
- 1994-04-29
- Volume
- 264
- Issue
- 5159
- Pages
- 707-710
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2030829559
- Cited by
- 396
- References
- 1
- FWCI
- 12.94
- Type
- journal article
- Language
- en
- Open access
- closed
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- Crowe, P. D., VanArsdale, T. L., Walter, B. N., Ware, C. F., Hession, C., Ehrenfels, B., Browning, J. L., Din, W. S., Goodwin, R. G., & Smith, C. A. (1994). A Lymphotoxin-β-Specific Receptor. Science. https://doi.org/10.1126/science.8171323
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