The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Hepatocellular Transplantation for Metabolic Deficiencies: Decrease of Plasma Bilirubin in Gunn Rats
Abstract
A sustained decrease of plasma bilirubin concentrations occurred in homozygous recessive Gunn rats lacking the enzyme uridine diphosphate glucuronyltransferase following infusion into the portal vein of hepatocytes from heterozygous nonjaundiced Gunn rats possessing the enzyme. Transplantation of cells capable of continuous enzyme production could be an effective mode of therapy for congenital enzyme deficiency diseases.
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Citations
Cites
A Portal Blood Factor as the Humoral Agent in Liver Regeneration
Fisher, B., Szuch, P., Levine, M., & Fisher, E. R. (1971) · Science · doi:10.1126/science.171.3971.575 · Cited by 161
Cited by
Human hepatocyte transplantation: current experience and future challenges
Dhawan, A., Puppi, J., Hughes, R. D., & Mitry, R. R. (2010) · Nature Reviews Gastroenterology & Hepatology · doi:10.1038/nrgastro.2010.44 · Cited by 362
Cell and tissue engineering for liver disease
Bhatia, S. N., Underhill, G. H., Zaret, K. S., & Fox, I. J. (2014) · Science Translational Medicine · doi:10.1126/scitranslmed.3005975 · Cited by 309
Isolated Hepatocyte Transplantation in an Infant With a Severe Urea Cycle Disorder
Horslen, S. P., McCowan, T. C., Goertzen, T. C., Warkentin, P. I., Cai, H. B., Strom, S. C., & Fox, I. J. (2003) · Pediatrics · doi:10.1542/peds.111.6.1262 · Cited by 295
Human hepatocyte transplantation for liver disease: current status and future perspectives
Iansante, V, Mitry, R. R., Filippi, C., Fitzpatrick, E., & Dhawan, A. (2018) · Pediatric Research · doi:10.1038/pr.2017.284 · Cited by 225
Horslen, S. P., & Fox, I. J. (2004) · Transplantation · doi:10.1097/01.tp.0000113809.53415.c2 · Cited by 119
Metadata
- Authors
- Matas, A. J., Sutherland, D. E. R., Steffes, M. W., Mauer, S. M., Sowe, A., Simmons, R. L., & Najarian, J. S.
- Venue
- Science
- Published
- 1976-05-28
- Volume
- 192
- Issue
- 4242
- Pages
- 892-894
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2056515335
- Cited by
- 294
- References
- 1
- FWCI
- 3.43
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Hepatocellular Transplantation for Metabolic Deficiencies: Decrease of Plasma Bilirubin in Gunn Rats. https://app.cochat.ai/papers/10.1126/science.818706
- The paper
- Matas, A. J., Sutherland, D. E. R., Steffes, M. W., Mauer, S. M., Sowe, A., Simmons, R. L., & Najarian, J. S. (1976). Hepatocellular Transplantation for Metabolic Deficiencies: Decrease of Plasma Bilirubin in Gunn Rats. Science. https://doi.org/10.1126/science.818706
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
