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Cited by 567

The DOI matches its Crossref record; 40 of the 40 references it cites were found in a registry or an index.

Structure and Functional Expression of a Member of the Low Voltage-Activated Calcium Channel Family

Soong, Tuck Wah, Stea, Anthony, Hodson, Connie D., Dubel, Stefan J., Vincent, Steven R., Snutch, Terry P.·1993·Science
DOI 10.1126/science.8388125
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Abstract

Oscillatory firing patterns are an intrinsic property of some neurons and have an important function in information processing. In some cells, low voltage-activated calcium channels have been proposed to underlie a depolarizing potential that regulates bursting. The sequence of a rat brain calcium channel α 1 subunit (rbE-II) was deduced. Although it is structurally related to high voltage-activated calcium channels, the rbE-II channel transiently activated at negative membrane potentials, required a strong hyperpolarization to deinactivate, and was highly sensitive to block by nickel. In situ hybridization showed that rbE-II messenger RNA is expressed in regions throughout the central nervous system. The electrophysiological properties of the rbE-II current are consistent with a type of low voltage-activated calcium channel that requires membrane hyperpolarization for maximal activity, which suggests that rbE-II may be involved in the modulation of firing patterns.

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Metadata

Authors
Soong, T. W., Stea, A., Hodson, C. D., Dubel, S. J., Vincent, S. R., & Snutch, T. P.
Venue
Science
Publisher
American Association for the Advancement of Science (AAAS)
Published
1993-05-21
Volume
260
Issue
5111
Pages
1133-1136
ISSN
  • 0036-8075 (ISSN-L)
  • 1095-9203
DOI
10.1126/science.8388125
OpenAlex
W1974015977
Cited by
567
References
40
FWCI
20.23
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Structure and Functional Expression of a Member of the Low Voltage-Activated Calcium Channel Family. https://app.cochat.ai/papers/10.1126/science.8388125
The paper
Soong, T. W., Stea, A., Hodson, C. D., Dubel, S. J., Vincent, S. R., & Snutch, T. P. (1993). Structure and Functional Expression of a Member of the Low Voltage-Activated Calcium Channel Family. Science. https://doi.org/10.1126/science.8388125

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.