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Cited by 337

The DOI matches its Crossref record; 80 of the 80 references it cites were found in a registry or an index.

The Status of the Gene Map of the Human Chromosomes: At least one gene on each chromosome of man is known; some chromosomes are extensively mapped.

McKusick, Victor A., Ruddle, Frank H.·1977·Science

Abstract

In man, the specific chromosome that carries each of about 210 gene loci is known. These loci include at least one assigned to each chromosome (including the Y), about 110 assigned to specific autosomes, and about 100 to the X chromosome. For many loci, information on regional chromosomal localization is also available. The information comes mainly from studies in families and somatic cell hybrids, as well as an integration of results from the two methods. Knowledge of the chromosome map gives insight into evolution, chromosomal organization in relation to genetic control mechanisms, and the pathogenesis of neoplasms and malformations. Furthermore, it is useful in prenatal or premorbid diagnosis of hereditary diseases.

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Crossref · 10.1126/science.850784

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Metadata

Authors
McKusick, V. A., & Ruddle, F. H.
Venue
Science
Published
1977-04-22
Volume
196
Issue
4288
Pages
390-405
ISSN
  • 0036-8075 (ISSN-L)
  • 1095-9203
OpenAlex
W2071741589
Cited by
337
References
80
FWCI
43.76
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: The Status of the Gene Map of the Human Chromosomes: At least one gene on each chromosome of man is known; some chromosomes are extensively mapped. https://app.cochat.ai/papers/10.1126/science.850784
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McKusick, V. A., & Ruddle, F. H. (1977). The Status of the Gene Map of the Human Chromosomes: At least one gene on each chromosome of man is known; some chromosomes are extensively mapped. Science. https://doi.org/10.1126/science.850784

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.