The DOI matches its Crossref record; 37 of the 37 references it cites were found in a registry or an index.
Human Cell Hybrids: Analysis of Transformation and Tumorigenicity
Abstract
Intraspecific human-human cell hybrids provide a stable model system with which to investigate the genetic control of transformed and tumorigenic phenotypes. Using this system it has been shown that these phenotypes are under separate genetic control. Furthermore, the tumorigenic phenotype can be complemented by fusion of different tumorigenic cells, resulting in nontumorigenic hybrids. This system also provides information on the control of differentiated function. Molecular cytogenetic techniques should reveal the nature of the chromosomal control of neoplastic transformation.
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Citations
Cites
Selection of Hybrids from Matings of Fibroblasts in vitro and Their Presumed Recombinants
Littlefield, J. W. (1964) · Science · doi:10.1126/science.145.3633.709 · Cited by 2,071
The Age Distribution of Cancer and a Multi-stage Theory of Carcinogenesis
Armitage, P., & Doll, R. (1954) · British Journal of Cancer · doi:10.1038/bjc.1954.1 · Cited by 1,549
Herberman, R. B., Nunn, M. E., & Lavrin, D. H. (1975) · International Journal of Cancer · doi:10.1002/ijc.2910160204 · Cited by 1,355
DNA-mediated transfer of the adenine phosphoribosyltransferase locus into mammalian cells.
Wigler, M., Pellicer, A., Silverstein, S., Axel, R., Urlaub, G., & Chasin, L. (1979) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.76.3.1373 · Cited by 1,279
Shin, S. I., Freedman, V. H., Risser, R., & Pollack, R. (1975) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.72.11.4435 · Cited by 738
Alteration of Cell-Surface Proteins by Viral Transformation and by Proteolysis
Hynes, R. O. (1973) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.70.11.3170 · Cited by 659
HARRIS, H., & WATKINS, J. F. (1965) · Nature · doi:10.1038/205640a0 · Cited by 606
Suppression of Malignancy by Cell Fusion
HARRIS, H., MILLER, O. J., KLEIN, G., WORST, P., & TACHIBANA, T. (1969) · Nature · doi:10.1038/223363a0 · Cited by 604
Differentiation of the epidermal keratinocyte in cell culture: Formation of the cornified envelope
Sun, T.-T., & Green, H. (1976) · Cell · doi:10.1016/0092-8674(76)90033-7 · Cited by 508
A General Theory of Carcinogenesis
Comings, D. E. (1973) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.70.12.3324 · Cited by 459
Cited by
Genes specifically expressed at growth arrest of mammalian cells
Schneider, C., King, R. M., & Philipson, L. (1988) · Cell · doi:10.1016/s0092-8674(88)91065-3 · Cited by 964
Santos, E., Martin-Zanca, D., Reddy, E. P., Pierotti, M. A., Della Porta, G., & Barbacid, M. (1984) · Science · doi:10.1126/science.6695174 · Cited by 418
Mehta, P. P., Bertram, J. S., & Loewenstein, W. R. (1986) · Cell · doi:10.1016/0092-8674(86)90497-6 · Cited by 408
Oncogene Activation in Chemical Carcinogenesis
(1988) · Advances in Cancer Research · doi:10.1016/s0065-230x(08)60222-5 · Cited by 388
Pereira-Smith, O. M., & Smith, J. R. (1988) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.85.16.6042 · Cited by 351
Metadata
- Authors
- Stanbridge, E. J., Der, C. J., Doersen, C.-J., Nishimi, R. Y., Peehl, D. M., Weissman, B. E., & Wilkinson, J. E.
- Venue
- Science
- Published
- 1982-01-15
- Volume
- 215
- Issue
- 4530
- Pages
- 252-259
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W1988088718
- Cited by
- 340
- References
- 37
- FWCI
- 15.81
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Human Cell Hybrids: Analysis of Transformation and Tumorigenicity. https://app.cochat.ai/papers/10.1126/science.7053574
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- Stanbridge, E. J., Der, C. J., Doersen, C.-J., Nishimi, R. Y., Peehl, D. M., Weissman, B. E., & Wilkinson, J. E. (1982). Human Cell Hybrids: Analysis of Transformation and Tumorigenicity. Science. https://doi.org/10.1126/science.7053574
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
