The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.
Natural light-gated anion channels: A family of microbial rhodopsins for advanced optogenetics
Open accessAbstract
Silencing neurons using optogenetics: Rhodopsin light-sensitive ion channels from green algae provide a powerful tool to control neuronal circuits. Rhodopsin cation channels effectively depolarize neurons and cause the firing of short-lived electrical membrane potentials. Govorunova et al. describe algal channels that do the opposite; that is, they hyperpolarize or silence particular neurons (see the Perspective by Berndt and Deisseroth). These cation channels provide greater light sensitivity than that of existing hyperpolarizing light-activated channels, operate rapidly, and selectively conduct only anions. This approach is an ideal complement to the widely used technique of creating light-sensitive neurons through the expression of rhodopsin cation channels. Science , this issue p. 647 ; see also p. 590
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Cites
Independent optical excitation of distinct neural populations
Klapoetke, N. C., Murata, Y., Kim, S. S., Pulver, S. R., Birdsey-Benson, A., Cho, Y. K., Morimoto, T. K., Chuong, A. S., Carpenter, E. J., Tian, Z., et al. (2014) · Nature Methods · doi:10.1038/nmeth.2836 · Cited by 2,344
Quantitative ultrastructural analysis of hippocampal excitatory synapses
Schikorski, T., & Stevens, C. F. (1997) · The Journal of Neuroscience · doi:10.1523/jneurosci.17-15-05858.1997 · Cited by 997
Algal genomes reveal evolutionary mosaicism and the fate of nucleomorphs
Curtis, B. A., Tanifuji, G., Burki, F., Gruber, A., Irimia, M., Maruyama, S., Arias, M. C., Ball, S. G., Gile, G. H., Hirakawa, Y., et al. (2012) · Nature · doi:10.1038/nature11681 · Cited by 417
Noninvasive optical inhibition with a red-shifted microbial rhodopsin
Chuong, A. S., Miri, M. L., Busskamp, V., Matthews, G. A. C., Acker, L. C., Sørensen, A. T., Young, A., Klapoetke, N. C., Henninger, M. A., Kodandaramaiah, S. B., et al. (2014) · Nature Neuroscience · doi:10.1038/nn.3752 · Cited by 33
Cited by
Integration of optogenetics with complementary methodologies in systems neuroscience
Kim, C. K., Adhikari, A., & Deisseroth, K. (2017) · Nature reviews. Neuroscience · doi:10.1038/nrn.2017.15 · Cited by 690
Next-generation probes, particles, and proteins for neural interfacing
Rivnay, J., Wang, H., Fenno, L., Deisseroth, K., & Malliaras, G. G. (2017) · Science Advances · doi:10.1126/sciadv.1601649 · Cited by 514
Genetic Dissection of Neural Circuits: A Decade of Progress
Luo, L., Callaway, E. M., & Svoboda, K. (2018) · Neuron · doi:10.1016/j.neuron.2018.03.040 · Cited by 448
Microbial Rhodopsins: Diversity, Mechanisms, and Optogenetic Applications
Govorunova, E. G., Sineshchekov, O. A., Li, H., & Spudich, J. L. (2017) · Annual Review of Biochemistry · doi:10.1146/annurev-biochem-101910-144233 · Cited by 363
Self-citationSilencing Neurons: Tools, Applications, and Experimental Constraints
Wiegert, J. S., Mahn, M., Prigge, M., Printz, Y., & Yizhar, O. (2017) · Neuron · doi:10.1016/j.neuron.2017.06.050 · Cited by 312
Metadata
- Authors
- Govorunova, E. G., Sineshchekov, O. A., Janz, R., Liu, X., & Spudich, J. L.
- Venue
- Science
- Published
- 2015-08-07
- Volume
- 349
- Issue
- 6248
- Pages
- 647-650
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W1788106766
- Cited by
- 690
- References
- 4
- FWCI
- 25.29
- Type
- journal article
- Language
- en
- Open access
- green
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