Sestrin2 is a leucine sensor for the mTORC1 pathway

Cited by (998)

Items 401–500 of 998

1. Direct sensing of dietary ω-6 linoleic acid through FABP5-mTORC1 signaling
   Nikos Koundouros, Michal J. Nagiec, Nayah Bullen, Evan Noch, Guillermo Burgos-Barragan, Zhongchi Li, Long He, Sungyun Cho, Bobak Parang, Dominique Leone et al. · 2025 · Science
2. mTOR Complexes as a Nutrient Sensor for Driving Cancer Progression
   Mio Harachi, Kenta Masui, Yukinori Okamura, Ryota Tsukui, Paul S. Mischel, Noriyuki Shibata · 2018 · International Journal of Molecular Sciences
3. The amino acid transporter Slc7a5 regulates the mTOR pathway and is required for granule cell development
   Aidan M. Sokolov, Jennie C. Holmberg, David M Feliciano · 2020 · Human Molecular Genetics
4. SESN2 protects against denervated muscle atrophy through unfolded protein response and mitophagy
   Xiaofan Yang, Pingping Xue, Meng Yuan, Xiang Xu, Cheng Wang, Wenqing Li, Hans‐Günther Machens, Zhenbing Chen · 2021 · Cell Death and Disease
5. Lysosomes at the Crossroads of Cell Metabolism, Cell Cycle, and Stemness
   Ada Nowosad, Arnaud Besson · 2022 · International Journal of Molecular Sciences
6. An update on the bridging factors connecting autophagy and Nrf2 antioxidant pathway
   Baike Ning, Shuqi Hang, Wenhe Zhang, Caiwen Mao, Dan Li · 2023 · Frontiers in Cell and Developmental Biology
7. Regulation of nucleo-cytosolic 26S proteasome translocation by aromatic amino acids via mTOR is essential for cell survival under stress
   Ido Livneh, Victoria Cohen‐Kaplan, Bertrand Fabre, Ifat Abramovich, Lulu Chen, Nishanth Belugali Nataraj, Ikrame Lazar, Tamar Ziv, Yosef Yarden, Yaniv Zohar et al. · 2023 · Molecular Cell
8. Sestrin2 reduces ferroptosis via the Keap1/Nrf2 signaling pathway after intestinal ischemia-reperfusion
   Lele Zhang, Ke Ding, Shishi Liao, Yi-guo Zhang, Hui-Yang Liao, Rong Chen, Qingtao Meng · 2024 · Free Radical Biology and Medicine
9. Branched-Chain Amino Acids in Liver Diseases: Complexity and Controversy
   Yaqi Zhang, Luqi Zhan, Lingjian Zhang, Qingmiao Shi, Lanjuan Li · 2024 · Nutrients
10. Inhibition of BCAT1-mediated cytosolic leucine metabolism regulates Th17 responses via the mTORC1-HIF1α pathway
    Yeon Jun Kang, Woorim Song, Su Jeong Lee, Seung Ah Choi, Sihyun Chae, Bo Ruem Yoon, Hee Young Kim, Jung Ho Lee, Chulwoo Kim, Joo‐Youn Cho et al. · 2024 · Experimental & Molecular Medicine
11. The emerging role of dysregulated propionate metabolism and methylmalonic acid in metabolic disease, aging, and cancer
    Moniquetta Shafer, Vivien Low, Zhongchi Li, John Blenis · 2025 · Cell Metabolism
12. Autophagic Mechanism in Anti-Cancer Immunity: Its Pros and Cons for Cancer Therapy
    Ying-Ying Li, Lynn G. Feun, Angkana Thongkum, Chiao-Hui Tu, Shu-Mei Chen, Medhi Wangpaichitr, Chunjing Wu, Macus Tien Kuo, Niramol Savaraj · 2017 · International Journal of Molecular Sciences
13. Src regulates amino acid-mediated mTORC1 activation by disrupting GATOR1-Rag GTPase interaction
    Rituraj Pal, Michela Palmieri, Arindam Chaudhury, Tiemo Jürgen Klisch, Alberto di Ronza, Joel R. Neilson, George Gerald Rodney, Marco Sardiello · 2018 · Nature Communications
14. Mammalian Target of Rapamycin
    Matthew F. Wipperman, David C. Montrose, Antonio M. Gotto, David P. Hajjar · 2019 · American Journal Of Pathology
15. Structural Insights into TOR Signaling
    Lucas Tafur, Jennifer M. Kefauver, Robbie Loewith · 2020 · Genes
16. Mechanism of Activation of Mechanistic Target of Rapamycin Complex 1 by Methionine
    Munehiro Kitada, Jing Xu, Yoshio Ogura, Itaru Monno, Daisuke Koya · 2020 · Frontiers in Cell and Developmental Biology
17. The role of nuclear Ca2+ in maintaining neuronal homeostasis and brain health
    Paweł Mozolewski, Maciej Jeziorek, Christoph Schuster, Hilmar Bading, Bess E Frost, Radek Dobrowolski · 2021 · Journal of Cell Science
18. The regulation of healthspan and lifespan by dietary amino acids
    Reji Babygirija, Dudley W. Lamming · 2021 · Translational Medicine of Aging
19. A glutamine sensor that directly activates TORC1
    Mirai Tanigawa, Katsuyoshi Yamamoto, Satoru Nagatoishi, Koji Nagata, Daisuke Noshiro, Nobuo N. Noda, Kouhei Tsumoto, Tatsuya Maeda · 2021 · Communications Biology
20. Leucine Supplementation in Cancer Cachexia: Mechanisms and a Review of the Pre-Clinical Literature
    Anna G. Beaudry, Michelle L. Law · 2022 · Nutrients
21. Long non‐coding RNAs in cancer metabolism
    Zhen‐Dong Xiao, Li Zhuang, Boyi Gan · 2016 · BioEssays
22. mTOR Signaling Pathway and Gut Microbiota in Various Disorders: Mechanisms and Potential Drugs in Pharmacotherapy
    Yuan Gao, Tian Tian · 2023 · International Journal of Molecular Sciences
23. p300 nucleocytoplasmic shuttling underlies mTORC1 hyperactivation in Hutchinson–Gilford progeria syndrome
    Sung Min Son, So Jung Park, Sophia Y. Breusegem, Delphine Larrieu, David Chaim Rubinsztein · 2024 · Nature Cell Biology
24. Sestrin2 drives ER-phagy in response to protein misfolding
    Chiara De Leonibus, Marianna Maddaluno, Rosa Ferriero, Roberta Besio, Laura Cinque, Pei Jin Lim, Alessandro Palma, Rossella De Cegli, Salvatore Gagliotta, Sandro Montefusco et al. · 2024 · Developmental Cell
25. Cytosolic acetyl-coenzyme A is a signalling metabolite to control mitophagy
    Yifan Zhang, Xiao Li Shen, Yuan Shen, Chao Wang, Cheng‐Ping Yu, Jiangxue Han, Siyi Cao, Lin Qian, Miaolian Ma, Shijing Huang et al. · 2025 · Nature
26. Sensors for the mTORC1 pathway regulated by amino acids
    Xiu-zhi Li, Xianghua Yan · 2019 · Journal of Zhejiang University SCIENCE B
27. Supply of methionine and arginine alters phosphorylation of mechanistic target of rapamycin (mTOR), circadian clock proteins, and α-s1-casein abundance in bovine mammary epithelial cells
    Liangyu Hu, Yifei Chen, Ismael Martínez-Cortés, D.N. Coleman, Hongyu Dai, Yusheng Liang, C. Parys, C. Fernández, Mengzhi Wang, Juan J. Loor · 2020 · Food & Function
28. mTOR complex 2 is an integrator of cancer metabolism and epigenetics
    Kenta Masui, Mio Harachi, Webster K. Cavenee, Paul S. Mischel, Noriyuki Shibata · 2020 · Cancer Letters
29. Deubiquitinase OTUD5 modulates mTORC1 signaling to promote bladder cancer progression
    Tao Hou, Weichao Dan, Tianjie Liu, Bo Liu, Yi Wei, Chenyang Yue, Taotao Que, Bohan Ma, Yuzeshi Lei, Zixi Wang et al. · 2022 · Cell Death and Disease
30. Brain-enriched RagB isoforms regulate the dynamics of mTORC1 activity through GATOR1 inhibition
    Gianluca Figlia, Sandra Müller, Anna M. Hagenston, Susanne Kleber, Mykola Roiuk, Jan-Philipp Quast, Nora ten Bosch, Damian Carvajal Ibañez, Daniela Mauceri, Ana Martín-Villalba et al. · 2022 · Nature Cell Biology
31. mTORC1 beyond anabolic metabolism: Regulation of cell death
    Jiajun Zhu, Hua Wang, Xuejun Jiang · 2022 · The Journal of Cell Biology
32. Structural insight into the arginine-binding specificity of CASTOR1 in amino acid-dependent mTORC1 signaling
    Xia, Jing, Wang, Rong, Zhang, Tianlong, Ding, Jianping · 2016 · Cell Discovery
33. A conformational change in the N terminus of SLC38A9 signals mTORC1 activation
    Hsiang‐Ting Lei, Xuelang Mu, Johan Hattne, Tamir Gonen · 2020 · Structure
34. Sensing the Environment Through Sestrins: Implications for Cellular Metabolism
    Anita Parmigiani, Andrei V. Budanov · 2016 · International review of cytology
35. Branched-Chain Amino Acid Negatively Regulates KLF15 Expression via PI3K-AKT Pathway
    Yunxia Liu, Weibing Dong, Jing Shao, Yibin Wang, Meiyi Zhou, Haipeng Sun · 2017 · Frontiers in Physiology
36. Defective interplay between mTORC1 activity and endoplasmic reticulum stress-unfolded protein response in uremic vascular calcification
    Dibyendu K. Panda, Xiuying Bai, Yves Sabbagh, Yan Zhang, Hans C. Zaun, Angeliki Karellis, Antonis E. Koromilas, Mark L. Lipman, Andrew C. Karaplis · 2018 · American Journal of Physiology-Renal Physiology
37. Nutrient Control of mRNA Translation
    Xin Erica Shu, Robert V. Swanda, Shu‐Bing Qian · 2020 · Annual Review of Nutrition
38. Sestrin2 as a potential therapeutic target for cardiovascular diseases
    Anbo Gao, Feng Li, Qun Zhou, Linxi Chen · 2020 · Pharmacological Research
39. Amino Acids in Cell Signaling: Regulation and Function.
    Sudikshya Paudel, Guo-Yao Wu, Xiao-Qiu Wang · 2021 · Advances in Experimental Medicine and Biology
40. Nutrients in the fate of pluripotent stem cells
    Vivian Lu, Irena J. Roy, Michael A. Teitell · 2021 · Cell Metabolism
41. Protein metabolism and related body function: mechanistic approaches and health consequences
    Daniel Tomé, Simon Benoit, Dalila Azzout‐Marniche · 2020 · Proceedings of The Nutrition Society
42. Elucidating the underlying mechanism of amino acids to regulate muscle protein synthesis: Effect on human health
    Xiaokang Lv, Chuanshe Zhou, Qiongxian Yan, Zhiliang Tan, Jinhe Kang, Shaoxun Tang · 2022 · Nutrition
43. Amino acid sensing and lysosomal signaling complexes
    Zhicheng Cui, Aaron M.N. Joiner, Rachel M. Jansen, James H. Hurley · 2023 · Current Opinion in Structural Biology
44. A cellular and molecular basis of leptin resistance
    Bowen Tan, Kristina Hedbacker, Leah Kelly, Zhaoyue Zhang, Alexandre Moura‐Assis, Ji‐Dung Luo, Joshua D. Rabinowitz, Jeffrey M. Friedman · 2025 · Cell Metabolism
45. Probing the mechanisms underlying human diseases in making ribosomes
    Katherine I. Farley‐Barnes, Susan J. Baserga · 2016 · Biochemical Society Transactions
46. Extracellular Glutamate-Induced mTORC1 Activation via the IR/IRS/PI3K/Akt Pathway Enhances the Expansion of Porcine Intestinal Stem Cells.
    Min Zhu, Ying-chao Qin, Chun-Qi Gao, Huichao Yan, Xiang-Guang Li, Xiu-Qi Wang · 2019 · Journal of Agricultural and Food Chemistry
47. Indoximod opposes the immunosuppressive effects mediated by IDO and TDO via modulation of AhR function and activation of mTORC1
    Erik L. Brincks, James Adams, Lifu Wang, Benjamin A. Turner, Agnieszka Marcinowicz, Jiyuan Ke, Michael Essmann, Lucía M. Mautino, Clarissa Van Allen, Sanjeev Kumar et al. · 2020 · Oncotarget
48. The Roles of Post-Translational Modifications on mTOR Signaling
    Shasha Yin, Liu Liu, Wenjian Gan · 2021 · International Journal of Molecular Sciences
49. Signatures and Clinical Significance of Amino Acid Flux in Sarcopenia: A Systematic Review and Meta-Analysis
    Miao Dai, Taiping Lin, Jirong Yue, Lunzhi Dai · 2021 · Frontiers in Endocrinology
50. Inhibitory Effect of Sestrin 2 on Hepatic Stellate Cell Activation and Liver Fibrosis
    Ji Hye Yang, Kyu Min Kim, Sam Seok Cho, Sang Mi Shin, Sun O Ka, Chang-Su Na, Byung Hyun Park, Kyung Hwan Jegal, Jae Kwang Kim, Sae‐Kwang Ku et al. · 2019 · Antioxidants and Redox Signaling
51. Lactalbumin, Not Collagen, Augments Muscle Protein Synthesis with Aerobic Exercise
    Sara Y. Oikawa, Martin J. MacInnis, Thomas R. Tripp, Chris McGlory, Steven K. Baker, Stuart M. Phillips · 2019 · Medicine & Science in Sports & Exercise
52. Amino Acid Oncometabolism and Immunomodulation of the Tumor Microenvironment in Lung Cancer
    Johannes Francois Fahrmann, Jody V. Vykoukal, Edwin Justin Ostrin · 2020 · Frontiers in Oncology
53. Cryo-EM structure of the SEA complex
    L. Tafur, Kerstin Hinterndorfer, C. Gabus, Chiara Lamanna, A. Bergmann, Y. Sadian, F. Hamdi, F. Kyrilis, P. Kastritis, R. Loewith · 2022 · Nature
54. Lysine crotonylation regulates leucine-deprivation-induced autophagy by a 14-3-3ε-PPM1B axis.
    Z. Zheng, Guokai Yan, Xiuzhi Li, Yu-Ke Fei, Ling-Ling Sun, Hao-Nan Yu, Yao-Rong Niu, Wei-Hua Gao, Qing Zhong, Xiang-Hua Yan · 2022 · Cell Reports
55. An evolutionary mechanism to assimilate new nutrient sensors into the mTORC1 pathway
    Grace Y. Liu, Patrick Jouandin, Raymond E. Bahng, Norbert Perrimon, David M. Sabatini · 2024 · Nature Communications
56. Amino acid and small GTPase regulation of mTORC1
    Thu P. Nguyen, Anderson R. Frank, Jenna L. Jewell · 2017 · Cellular Logistics
57. Sestrin family – the stem controlling healthy ageing
    Alexander Haidurov, Andrei V. Budanov · 2020 · Mechanisms of Ageing and Development
58. Understanding the effects of nutrition and post-exercise nutrition on skeletal muscle protein turnover: Insights from stable isotope studies
    Sophie Joanisse, James McKendry, Changhyun Lim, Everson Araújo Nunes, Tanner Stokes, Jonathan C. Mcleod, Stuart M. Phillips · 2021 · Clinical Nutrition Open Science
59. Progress in research on the role of amino acid metabolic reprogramming in tumour therapy: A review
    Dong Wang, Xin Wan · 2022 · Biomedicine & Pharmacotherapy
60. Crosstalks between translation and metabolism in cancer
    Stefano Biffo, Nicola Manfrini, Sara Ricciardi · 2017 · Current Opinion in Genetics & Development
61. Cardiac Metabolism in Perspective
    Heinrich Taegtmeyer, Truong Lam, Giovanni Davogustto · 2016 · Comprehensive physiology
62. Leucine promotes protein synthesis of juvenile white shrimp Litopenaeus vannamei through TOR signaling pathway
    Zonglu Wei, Yutong Zhuang, Xinting Liu, Danyang Zou, Kangsen Mai, Zhenzhu Sun, Chaoxia Ye · 2022 · Aquaculture
63. Genome-wide CRISPR screens identify ILF3 as a mediator of mTORC1-dependent amino acid sensing
    Guokai Yan, Jinxin Yang, Wen Li, Ao Guo, Jialiang Guan, Ying Liu · 2023 · Nature Cell Biology
64. Essential amino acid ingestion alters expression of genes associated with amino acid sensing, transport, and mTORC1 regulation in human skeletal muscle
    Ted G. Graber, Michael S. Borack, Paul T. Reidy, Elena Volpi, Blake B. Rasmussen · 2017 · Nutrition & Metabolism
65. Equivalent Hypertrophy and Strength Gains in β-Hydroxy-β-Methylbutyrate- or Leucine-supplemented Men
    JAKUBOWSKI, JOSEPHINE S., WONG, EDWIN P. T., NUNES, EVERSON A., NOGUCHI, KENNETH S., VANDEWEERD, JOSHUA K., MURPHY, KEVIN T., MORTON, ROBERT W., MCGLORY, CHRIS, PHILLIPS, STUART M. · 2019 · Medicine & Science in Sports & Exercise
66. Molecular Basis of White Adipose Tissue Remodeling That Precedes and Coincides With Hibernation in the Syrian Hamster, a Food-Storing Hibernator
    Yuichi Chayama, Lisa Ando, Yuya Sato, Shuji Shigenobu, Daisuke Anegawa, Takayuki Fujimoto, Taii Hiroki, Yutaka Tamura, Masayuki Miura, Yoshifumi Yamaguchi · 2019 · Frontiers in Physiology
67. SESTRINs: Emerging Dynamic Stress-Sensors in Metabolic and Environmental Health
    Seung‐Hyun Ro, Julianne Fay, Cesar I. Cyuzuzo, Yura Jang, Naeun Lee, Hyun‐Seob Song, Edward N. Harris · 2020 · Frontiers in Cell and Developmental Biology
68. Monomethyl branched-chain fatty acid mediates amino acid sensing upstream of mTORC1
    Mengnan Zhu, Fukang Teng, Na Li, Li Zhang, Shuxian Zhang, Fan Xu, Jing Shao, Haipeng Sun, Huanhu Zhu · 2021 · Developmental Cell
69. Amino Acid Signaling for TOR in Eukaryotes: Sensors, Transducers, and a Sustainable Agricultural fuTORe
    Nanticha Lutt, Jacob O. Brunkard · 2022 · Biomolecules
70. Inhibition of Glutamine Uptake Resensitizes Paclitaxel Resistance in SKOV3-TR Ovarian Cancer Cell via mTORC1/S6K Signaling Pathway
    Gyeongmi Kim, Se‐Kyeong Jang, Yu Jin Kim, Hyeon‐Ok Jin, Seunghee Bae, Jungil Hong, In‐Chul Park, Jae Ho Lee · 2022 · International Journal of Molecular Sciences
71. Calycosin induces autophagy and apoptosis via Sestrin2/AMPK/mTOR in human papillary thyroid cancer cells
    Na Qu, Junsheng Qu, Na Huang, Kexin Zhang, Tongtong Ye, Junfeng Shi, Bing Chen, Chengxia Kan, Jingwen Zhang, Fang Han et al. · 2022 · Frontiers in Pharmacology
72. Ring domains are essential for GATOR2-dependent mTORC1 activation
    Cong Jiang, Xiaoming Dai, Shaohui He, Hongfei Zhou, Lan Fang, Jianping Guo, Songlei Liu, Tao Zhang, Weijuan Pan, Haihong Yu et al. · 2022 · Molecular Cell
73. Metabolic changes with the occurrence of atherosclerotic plaques and the effects of statins
    Lingmin Zhao, Di Ma, Lijuan Wang, Xingqi Su, Liangshu Feng, LiChong Zhu, Ying Chen, Yulei Hao, XinYu Wang, Jiachun Feng · 2023 · Frontiers in Immunology
74. The role of branched-chain amino acids and their downstream metabolites in mediating insulin resistance
    Abdualrahman Mohammed Abdualkader, Qutuba G. Karwi, Gary D. Lopaschuk, Rami Al Batran · 2024 · Journal of Pharmacy & Pharmaceutical Sciences
75. Nutrient sensing of mTORC1 signaling in cancer and aging
    Cong Jiang, Xiao Tan, Ning Liu, Peiqiang Yan, Tao Hou, Wenyi Wei · 2024 · Seminars in Cancer Biology
76. Rag–Ragulator is the central organizer of the physical architecture of the mTORC1 nutrient-sensing pathway
    Max L. Valenstein, Pranav V. Lalgudi, Xin Gu, Jibril F. Kedir, Martin S. Taylor, Raghu R. Chivukula, David M. Sabatini · 2024 · Proceedings of the National Academy of Sciences
77. BCAT1 promotes proliferation of endometrial cancer cells through reprogrammed BCAA metabolism.
    Ping Wang, Shouheng Wu, Xiaofeng Zeng, Yaqing Zhang, Ying Zhou, Liuli Su, Wei Yu Lin · 2018 · Europe PMC (PubMed Central)
78. Oryzanol Attenuates High Fat and Cholesterol Diet-Induced Hyperlipidemia by Regulating the Gut Microbiome and Amino Acid Metabolism
    Sisi Yan, Jihong Chen, Lingfeng Zhu, Tianyi Guo, Dandan Qin, Zuomin Hu, Shuai Han, Yaping Zhou, Otobong Donald Akan, Ji Wang et al. · 2022 · Journal of Agricultural and Food Chemistry
79. Pharmacologic inhibition of LAT1 predominantly suppresses transport of large neutral amino acids and downregulates global translation in cancer cells
    Kou Nishikubo, Ryuichi Ohgaki, Hiroki Okanishi, Suguru Okuda, Minhui Xu, Hitoshi Endou, Yoshikatsu Kanai · 2022 · Journal of Cellular and Molecular Medicine
80. CDK5-PRMT1-WDR24 signaling cascade promotes mTORC1 signaling and tumor growth
    Shasha Yin, Liu Liu, Lauren Elizabeth Ball, Yalong Wang, Mark T. Bedford, Stephen A. Duncan, Haizhen Wang, Wenjian Gan · 2023 · Cell Reports
81. Proliferating Helper T Cells Require Rictor/mTORC2 Complex to Integrate Signals from Limiting Environmental Amino Acids
    Lee-Ann Van de Velde, Peter J. Murray · 2016 · Journal of Biological Chemistry
82. Branched‐Chain Amino Acid Accumulation Fuels the Senescence‐Associated Secretory Phenotype
    Yaosi Liang, Christopher C. Pan, Tao Yin, Lu Wang, Xia Gao, Ergang Wang, Holly Quang, De Huang, Lianmei Tan, Kun Xiang et al. · 2023 · Advanced Science
83. The rapid proximity labeling system PhastID identifies ATP6AP1 as an unconventional GEF for Rheb
    Ran Feng, Feng Liu, Ruofei Li, Zhifen Zhou, Zhuoheng Lin, Lin Song, Shengcheng Deng, Yingying Li, Baoting Nong, Ying Xia et al. · 2024 · Cell Research
84. Germline BRCA1 mutation reprograms breast epithelial cell metabolism towards mitochondrial-dependent biosynthesis: evidence for metformin-based “starvation” strategies in BRCA1 carriers
    Elisabet Cuyàs, Salvador Fernández‐Arroyo, Tomás Alarcón, Ruth Lupu, Jorge Joven, Javier Abel Menéndez · 2016 · Oncotarget
85. Energy metabolism profile of the effects of amino acid treatment on hepatocytes: Phenylalanine and phenylpyruvate inhibit glycolysis of hepatocytes
    Reiko Suzuki, Yoriko Sato, Misato Fukaya, Daisuke Suzuki, Fumiaki Yoshizawa, Yusuke Sato · 2020 · Nutrition
86. CBS and MAT2A improve methionine‐mediated DNA synthesis through SAMTOR/mTORC1/S6K1/CAD pathway during embryo implantation
    Shuang Cai, Qianhong Ye, Xiangzhou Zeng, Guangxin Yang, Changchuan Ye, Meixia Chen, Haitao Yu, Yuming Wang, Gang Wang, Shuo Huang et al. · 2020 · Cell Proliferation
87. ArfGAP1 inhibits mTORC1 lysosomal localization and activation
    Delong Meng, Qianmei Yang, Chase H. Melick, Brenden C. Park, Ting‐Sung Hsieh, Adna Curukovic, Mi‐Hyeon Jeong, Junmei Zhang, Nicholas G. James, Jenna L. Jewell · 2021 · The EMBO Journal
88. Aberrant branched-chain amino acid catabolism in cardiovascular diseases
    Yixiao Xiong, Ling Jiang, Tao Li · 2022 · Frontiers in Cardiovascular Medicine
89. Targeting fatty acid uptake and metabolism in cancer cells: A promising strategy for cancer treatment
    Rahul Mallick, Prasenjit Bhowmik, Asim K. Duttaroy · 2023 · Biomedicine & Pharmacotherapy
90. Feed Intake Regulation in Fish: Implications for Aquaculture
    Jose Luis Soengas, Sara Comesaña, Ayelén Melisa Blanco, Marta Conde‐Sieira · 2024 · Reviews in Fisheries Science & Aquaculture
91. Amino acids in cancer: Understanding metabolic plasticity and divergence for better therapeutic approaches
    Linda K. Do, Hyun Min Lee, Yun‐Sok Ha, Chan‐Hyeong Lee, Jiyeon Kim · 2025 · Cell Reports
92. Dynamin inhibitors block activation of mTORC1 by amino acids independently of dynamin
    Avinash K. Persaud, Yann Cormerais, Jacques Pouysségur, Daniela Rotin · 2018 · Journal of Cell Science
93. Modulation of the secretory pathway by amino-acid starvation
    Wessel van Leeuwen, Felix van der Krift, Cathérine Rabouille · 2018 · The Journal of Cell Biology
94. Regulation of Metabolic Disease-Associated Inflammation by Nutrient Sensors
    Alex Shimura Yamashita, Thiago Belchior, Fábio Santos Lira, NICOLETTE CLAIRE BISHOP, Barbara Wessner, José Cesar Rosa Neto, William T. Festuccia · 2018 · Mediators of Inflammation
95. Proteomic analyses reveal GNG12 regulates cell growth and casein synthesis by activating the Leu-mediated mTORC1 signaling pathway
    Chaochao Luo, Shengguo Zhao, Wenting Dai, Nan Zheng, Jiaqi Wang · 2018 · Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics
96. Implications of amino acid sensing and dietary protein to the aging process
    Oleh V. Lushchak, Olha M. Strilbytska, Ihor S. Yurkevych, Alexander M. Vaiserman, Kenneth B. Storey · 2018 · Experimental Gerontology
97. Skeletal muscle–specific knockout of DEP domain containing 5 protein increases mTORC1 signaling, muscle cell hypertrophy, and mitochondrial respiration
    Ted G. Graber, C. Fry, Camille R. Brightwell, Tatiana Moro, R. Maroto, N. Bhattarai, Craig Porter, M. Wakamiya, B. Rasmussen · 2019 · Journal of Biological Chemistry
98. Leucine Promotes Milk Synthesis in Bovine Mammary Epithelial Cells via the PI3K-DDX59 Signaling
    Youwen Qiu, Bo Qu, Zhen Zhen, Xiaohan Yuan, Li Zhang, Minghui Zhang · 2019 · Journal of Agricultural and Food Chemistry
99. Excessive BCAA regulates fat metabolism partially through the modification of m6A RNA methylation in weanling piglets
    Jinghui Heng, Zhihui Wu, Min Tian, Jiaming Chen, Hanqing Song, Fang Chen, Wutai Guan, Shihai Zhang · 2020 · Nutrition & Metabolism
100. Dietary protein, exercise, ageing and physical inactivity: interactive influences on skeletal muscle proteostasis
     Colleen S. Deane, Isabel A. Ely, Daniel James Wilkinson, Kenneth Smith, Bethan Eileen Phillips, Philip James Atherton · 2020 · Proceedings of The Nutrition Society