mTORC1 induces purine synthesis through control of the mitochondrial tetrahydrofolate cycle

Ben-Sahra, Issam, Hoxhaj, Gerta, Ricoult, Stéphane J. H., Asara, John M., Manning, Brendan D.·2016·Science

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Items 301–400 of 807

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  11. Amino Acid Transporters Are a Vital Focal Point in the Control of mTORC1 Signaling and Cancer
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  15. Structural Insights into TOR Signaling
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  19. Increased Expression of Serine Hydroxymethyltransferase 2 (SHMT2) is a Negative Prognostic Marker in Patients with Hepatocellular Carcinoma and is Associated with Proliferation of HepG2 Cells
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  20. Comprehensive multi-omics approaches reveal the hepatotoxic mechanism of perfluorohexanoic acid (PFHxA) in mice.
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  21. Hepatic mTORC1 signaling activates ATF4 as part of its metabolic response to feeding and insulin
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  24. FAM120A couples SREBP-dependent transcription and splicing of lipogenesis enzymes downstream of mTORC1
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  32. mTOR signaling in Brown and Beige adipocytes: implications for thermogenesis and obesity
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  55. Sequestration-Mediated Downregulation of de Novo Purine Biosynthesis by AMPK
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  60. mTOR Signaling as a Regulator of Hematopoietic Stem Cell Fate
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