The DOI matches its Crossref record; 43 of the 43 references it cites were found in a registry or an index.
A central neural circuit for itch sensation
Abstract
The circuits of itching and scratching: Itch is a major clinical problem with poor treatment options. In the past few years, much progress has been made in identifying itch-selective molecules and neurons. However, we know very little about the brain circuits underlying itch processing. Mu et al. found that a subpopulation of itch-processing neurons in the spinal cord directly excite other neurons that project to a brain stem structure called the parabrachial nucleus. Inhibition of this spino-parabrachial pathway reduced itching and scratching in mice. Science , this issue p. 695
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Cites
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Natural neural projection dynamics underlying social behavior
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Sensory Neuron-Specific GPCR Mrgprs Are Itch Receptors Mediating Chloroquine-Induced Pruritus
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A gastrin-releasing peptide receptor mediates the itch sensation in the spinal cord
Sun, Y.-G., & Chen, Z.-F. (2007) · Nature · doi:10.1038/nature06029 · Cited by 788
Self-citationA subpopulation of nociceptors specifically linked to itch
Han, L., Ma, C., Liu, Q., Weng, H.-J., Cui, Y., Tang, Z., Kim, Y., Nie, H., Qu, L., Patel, K. N., et al. (2013) · Nature Neuroscience · doi:10.1038/nn.3289 · Cited by 612
Cellular Basis of Itch Sensation
Sun, Y.-G., Zhao, Z.-Q., Meng, X.-L., Yin, J., Liu, X.-Y., & Chen, Z.-F. (2009) · Science · doi:10.1126/science.1174868 · Cited by 609
Self-citationSpinothalamic lamina I neurons selectively sensitive to histamine: a central neural pathway for itch
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Basal forebrain activation enhances cortical coding of natural scenes
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The Cells and Circuitry for Itch Responses in Mice
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Cited by
The Parabrachial Nucleus: CGRP Neurons Function as a General Alarm
Palmiter, R. D. (2018) · Trends in Neurosciences · doi:10.1016/j.tins.2018.03.007 · Cited by 431
Identifying the pathways required for coping behaviours associated with sustained pain
Huang, T., Lin, S.-H., Malewicz, N. M., Zhang, Y., Zhang, Y., Goulding, M., LaMotte, R. H., & Ma, Q. (2019) · Nature · doi:10.1038/s41586-018-0793-8 · Cited by 264
A Neural Circuit for the Suppression of Pain by a Competing Need State
Alhadeff, A. L., Su, Z., Hernandez, E., Klima, M. L., Phillips, S. Z., Holland, R. A., Guo, C., Hantman, A. W., De Jonghe, B. C., & Betley, J. N. (2018) · Cell · doi:10.1016/j.cell.2018.02.057 · Cited by 218
Peripheral itch sensitization in atopic dermatitis
Tominaga, M., & Takamori, K. (2022) · Allergology International · doi:10.1016/j.alit.2022.04.003 · Cited by 160
Itch: Pathogenesis and treatment
Sutaria, N., Adawi, W., Goldberg, R., Roh, Y. S., Choi, J., & Kwatra, S. G. (2022) · Journal of the American Academy of Dermatology · doi:10.1016/j.jaad.2021.07.078 · Cited by 130
Metadata
- Authors
- Mu, D., Deng, J., Liu, K.-F., Wu, Z.-Y., Shi, Y.-F., Guo, W.-M., Mao, Q.-Q., Liu, X.-J., Li, H., & Sun, Y.-G.
- Venue
- Science
- Published
- 2017-08-18
- Volume
- 357
- Issue
- 6352
- Pages
- 695-699
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2750013446
- Cited by
- 258
- References
- 43
- FWCI
- 14.76
- Type
- journal article
- Language
- en
- Open access
- closed
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- Mu, D., Deng, J., Liu, K.-F., Wu, Z.-Y., Shi, Y.-F., Guo, W.-M., Mao, Q.-Q., Liu, X.-J., Li, H., & Sun, Y.-G. (2017). A central neural circuit for itch sensation. Science. https://doi.org/10.1126/science.aaf4918
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