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The DOI matches its Crossref record; 45 of the 45 references it cites were found in a registry or an index.

Specificity, cross-reactivity, and function of antibodies elicited by Zika virus infection

Stettler, Karin, Beltramello, Martina, Espinosa, Diego A., Graham, Victoria, Cassotta, Antonino, Bianchi, Siro, Vanzetta, Fabrizia, Minola, Andrea, Jaconi, Stefano, Mele, Federico, Foglierini, Mathilde, Pedotti, Mattia, Simonelli, Luca, Dowall, Stuart, Atkinson, Barry, Percivalle, Elena, Simmons, Cameron P., Varani, Luca, Blum, Johannes, Baldanti, Fausto, Cameroni, Elisabetta, Hewson, Roger, Harris, Eva, Lanzavecchia, Antonio, Sallusto, Federica, Corti, Davide·2016·Science

Abstract

Characterizing the Zika virus antibody response: Given the public health emergency that Zika virus poses, scientists are seeking to understand the Zika-specific immune response. Stettler et al. analyzed 119 monoclonal antibodies isolated from four donors that were infected with Zika virus during the present epidemic, including two individuals that had previously been infected with dengue virus, another member of the flavivirus family. Neutralizing antibodies primarily recognized the envelope protein domain III (EDIII) or quaternary epitopes on the intact virus, and an EDIII-targeted antibody protected mice against lethal infection. Some EDI/II-targeting antibodies cross-reacted with dengue virus in vitro and could enhance disease in dengue-infected mice. Whether dengue and Zika virus antibodies cross-react in humans remains to be tested. Science , this issue p. 823

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Metadata

Authors
Stettler, K., Beltramello, M., Espinosa, D. A., Graham, V., Cassotta, A., Bianchi, S., Vanzetta, F., Minola, A., Jaconi, S., Mele, F., Foglierini, M., Pedotti, M., Simonelli, L., Dowall, S., Atkinson, B., Percivalle, E., Simmons, C. P., Varani, L., Blum, J., Baldanti, F., Cameroni, E., Hewson, R., Harris, E., Lanzavecchia, A., Sallusto, F., & Corti, D.
Venue
Science
Published
2016-08-19
Volume
353
Issue
6301
Pages
823-826
ISSN
  • 0036-8075 (ISSN-L)
  • 1095-9203
OpenAlex
W2469258508
Cited by
758
References
45
FWCI
113.96
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Specificity, cross-reactivity, and function of antibodies elicited by Zika virus infection. https://app.cochat.ai/papers/10.1126/science.aaf8505
The paper
Stettler, K., Beltramello, M., Espinosa, D. A., Graham, V., Cassotta, A., Bianchi, S., Vanzetta, F., Minola, A., Jaconi, S., Mele, F., Foglierini, M., Pedotti, M., Simonelli, L., Dowall, S., Atkinson, B., Percivalle, E., Simmons, C. P., Varani, L., Blum, J., . . . Corti, D. (2016). Specificity, cross-reactivity, and function of antibodies elicited by Zika virus infection. Science. https://doi.org/10.1126/science.aaf8505

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.