Systematic mapping of functional enhancer–promoter connections with CRISPR interference

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Items 201–300 of 674

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8. Systematic dissection of transcriptional regulatory networks by genome-scale and single-cell CRISPR screens
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12. A multiplexed gRNA piggyBac transposon system facilitates efficient induction of CRISPRi and CRISPRa in human pluripotent stem cells
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14. Lupus enhancer risk variant causes dysregulation of IRF8 through cooperative lncRNA and DNA methylation machinery
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21. Enhancer Talk
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22. CRISPR screens identify gene targets at breast cancer risk loci
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26. Cohesin-mediated 3D contacts tune enhancer-promoter regulation
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29. Interpreting cis-regulatory interactions from large-scale deep neural networks
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30. In vivo CRISPR screening for phenotypic targets of the mir-35-42 family in C. elegans
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31. Functional effects of variation in transcription factor binding highlight long-range gene regulation by epromoters
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32. Fetal Liver–Derived Alveolar-like Macrophages: A Self-Replicating Ex Vivo Model of Alveolar Macrophages for Functional Genetic Studies
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34. Using CRISPR to understand and manipulate gene regulation
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37. Parallel characterization of cis-regulatory elements for multiple genes using CRISPRpath
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38. CRISPR-FOCUS: A web server for designing focused CRISPR screening experiments
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39. Identifying Novel Enhancer Elements with CRISPR-Based Screens
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40. CRISPR Tools for Systematic Studies of RNA Regulation
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41. Methods and applications of in vivo CRISPR screening
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42. Epigenetic editing: from concept to clinic
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43. Application of CRISPR/Cas9 to the study of brain development and neuropsychiatric disease
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46. Activation of the imprinted Prader-Willi syndrome locus by CRISPR-based epigenome editing
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48. Connecting high-resolution 3D chromatin organization with epigenomics
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49. Decoding the noncoding genome via large-scale CRISPR screens
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51. Neuro-Immuno-Gene- and Genome-Editing-Therapy for Alzheimer’s Disease: Are We There Yet?
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53. The evaluation of active transcriptional repressor domain for CRISPRi in plants
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54. CRISP-view: a database of functional genetic screens spanning multiple phenotypes
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58. Advancing Stem Cell Models of Alpha-Synuclein Gene Regulation in Neurodegenerative Disease
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59. Extrachromosomal DNA associates with nuclear condensates and reorganizes chromatin structures to enhance oncogenic transcription
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62. Aneuploidy in human cancer: new tools and perspectives
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63. Gene-centric functional dissection of human genetic variation uncovers regulators of hematopoiesis
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65. BRCA1 mutations attenuate super-enhancer function and chromatin looping in haploinsufficient human breast epithelial cells
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68. CRISPR-Based Approaches for the High-Throughput Characterization of Long Non-Coding RNAs
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70. Activity-by-Contact model of enhancer specificity from thousands of CRISPR perturbations
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77. Massively parallel disruption of enhancers active in human neural stem cells
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80. CRTC1/MAML2 directs a PGC-1α-IGF-1 circuit that confers vulnerability to PPARγ inhibition
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100. Systematic identification of genomic elements that regulate FCGR2A expression and harbor variants linked with autoimmune disease
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