The DOI matches its Crossref record; 8 of the 8 references it cites were found in a registry or an index.
Universal protection against influenza infection by a multidomain antibody to influenza hemagglutinin
Open accessAbstract
Durable influenza protection: Vaccines are indispensable for the control and prevention of influenza, but there are several challenges to efficacy. Some individuals respond poorly to vaccination, and virus variation makes targeting optimal antigens difficult. Broadly neutralizing antibodies are one solution, but they have their own pitfalls, including limited cross-reactivity to both influenza A and B strains and the need for repeated injections. Now, Laursen et al. have developed multidomain antibodies with breadth and potency. Administered intranasally to mice with an adeno-associated virus vector, the antibodies provided durable and continuous protection from a panoply of influenza strains. Science , this issue p. 598
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Antibody Recognition of a Highly Conserved Influenza Virus Epitope
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Structure-guided multivalent nanobodies block SARS-CoV-2 infection and suppress mutational escape
Koenig, P.-A., Das, H., Liu, H., Kümmerer, B. M., Gohr, F. N., Jenster, L.-M., Schiffelers, L. D. J., Tesfamariam, Y. M., Uchima, M., Wuerth, J. D., et al. (2021) · Science · doi:10.1126/science.abe6230 · Cited by 396
Self-citationChen, Z.-S., Huang, H.-C., Wang, X., Schön, K., Jia, Y., Lebens, M., Besavilla, D. F., Murti, J. R., Ji, Y., Sarshad, A. A., et al. (2025) · Nature Communications · doi:10.1038/s41467-024-55193-y · Cited by 39
Metadata
- Authors
- Laursen, N. S., Friesen, R. H. E., Zhu, X., Jongeneelen, M., Blokland, S., Vermond, J., van Eijgen, A., Tang, C., van Diepen, H., Obmolova, G., van der Neut Kolfschoten, M., Zuijdgeest, D., Straetemans, R., Hoffman, R. M. B., Nieusma, T., Pallesen, J., Turner, H. L., Bernard, S. M., Ward, A. B., Luo, J., Poon, L. L. M., Tretiakova, A. P., Wilson, J. M., Limberis, M. P., Vogels, R., Brandenburg, B., Kolkman, J. A., & Wilson, I. A.
- Venue
- Science
- Published
- 2018-11-02
- Volume
- 362
- Issue
- 6414
- Pages
- 598-602
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2898721059
- Cited by
- 220
- References
- 8
- FWCI
- 17.05
- Type
- journal article
- Language
- en
- Open access
- green
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- The paper
- Laursen, N. S., Friesen, R. H. E., Zhu, X., Jongeneelen, M., Blokland, S., Vermond, J., van Eijgen, A., Tang, C., van Diepen, H., Obmolova, G., van der Neut Kolfschoten, M., Zuijdgeest, D., Straetemans, R., Hoffman, R. M. B., Nieusma, T., Pallesen, J., Turner, H. L., Bernard, S. M., Ward, A. B., . . . Wilson, I. A. (2018). Universal protection against influenza infection by a multidomain antibody to influenza hemagglutinin. Science. https://doi.org/10.1126/science.aaq0620
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
