Car t cell immunotherapy for human cancer

June, Carl H., O’Connor, Roddy S., Kawalekar, Omkar U., Ghassemi, Saba, Milone, Michael C.·2018·Science

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Items 401–500 of 1,007

  1. CAR‐T Cell Therapy in Cancer: Tribulations and Road Ahead
    Qingyang Zhang, Jieming Ping, Zirui Huang, Xiaoli Zhang, Jingyi Zhou, Gangyang Wang, Liu Shaoyang, Jianjun Ma · 2020 · Journal of Immunology Research
  2. An orthogonal IL-2 and IL-2Rβ system drives persistence and activation of CAR T cells and clearance of bulky lymphoma
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  3. CD137 (4-1BB) costimulation of CD8+ T cells is more potent when provided in cis than in trans with respect to CD3-TCR stimulation
    Itziar Otano, Arantza Azpilikueta, Javier Glez‐Vaz, Maite Álvarez, José Medina‐Echeverz, Iván Cortés‐Domínguez, Carlos Ortíz-de-Solórzano, Peter Ellmark, Sara Fritzell, Gabriela Hernández‐Hoyos et al. · 2021 · Nature Communications
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  5. Point mutation in CD19 facilitates immune escape of B cell lymphoma from CAR-T cell therapy
    Zhen Zhang, Xinfeng Chen, Yonggui Tian, Feng Li, Xuan Zhao, Jinyan Liu, Chang Yao, Yi Zhang · 2020 · Journal for ImmunoTherapy of Cancer
  6. Construction of PD1/CD28 chimeric-switch receptor enhances anti-tumor ability of c-Met CAR-T in gastric cancer
    Cong Chen, Yanmei Gu, Fan Zhang, Zheng-Chao Zhang, Yating Zhang, Yi-Di He, Ling Wang, Ning Zhou, Futian Tang, Hongjian Liu et al. · 2021 · OncoImmunology
  7. New Strategy for Promoting Vascularization in Tumor Spheroids in a Microfluidic Assay
    Wan, Zhengpeng, Floryan, Marie A., Coughlin, Mark F., Zhang, Shun, Zhong, Amy X., Shelton, Sarah E., Wang, Xun, Xu, Chenguang, Barbie, David A., Kamm, Roger D. · 2023 · Advanced Healthcare Materials
  8. The 2018 Nobel Prize in medicine goes to cancer immunotherapy
    Zong Sheng Guo · 2018 · BMC Cancer
  9. Immunocompetent cancer-on-chip models to assess immuno-oncology therapy
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  10. Highly Efficient Transfection of Human Primary T Lymphocytes Using Droplet-Enabled Mechanoporation
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  11. Immune-Cell-Derived Exosomes for Cancer Therapy
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  12. Research progress of interleukin-15 in cancer immunotherapy
    Menghan Cai, Xuan Huang, Xiting Huang, Dianwen Ju, Yi Zhun Zhu, Ye Li · 2023 · Frontiers in Pharmacology
  13. Mechanisms underlying CD19-positive ALL relapse after anti-CD19 CAR T cell therapy and associated strategies
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  14. Surmounting the obstacles that impede effective CAR T cell trafficking to solid tumors
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  15. High-throughput continuous-flow microfluidic electroporation of mRNA into primary human T cells for applications in cellular therapy manufacturing
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  16. Roles of Podoplanin in Malignant Progression of Tumor
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  17. M1 polarization enhances the antitumor activity of chimeric antigen receptor macrophages in solid tumors
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  18. Recent Advances in CAR-Based Solid Tumor Immunotherapy
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  19. The screening, identification, design and clinical application of tumor-specific neoantigens for TCR-T cells
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  20. Biomineralized Engineered Bacterial Outer Membrane Vesicles as cGAS-STING Nanoagonists Synergize with Lactate Metabolism Modulation to Potentiate Immunotherapy
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  21. CAR T cell product performance in haematological malignancies before and after marketing authorisation
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  26. Nano-immunotherapy: overcoming delivery challenge of immune checkpoint therapy
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  27. Human Lymph Nodes Maintain TCF-1hi Memory T Cells with High Functional Potential and Clonal Diversity throughout Life
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  29. The CNS and the Brain Tumor Microenvironment: Implications for Glioblastoma Immunotherapy
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  30. Equipping Cancer Cell Membrane Vesicles with Functional DNA as a Targeted Vaccine for Cancer Immunotherapy
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  31. Targeted inducible delivery of immunoactivating cytokines reprograms glioblastoma microenvironment and inhibits growth in mouse models
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  35. Tumor immune microenvironment modulation-based drug delivery strategies for cancer immunotherapy
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  36. CAR-T Cells Targeting Epstein-Barr Virus gp350 Validated in a Humanized Mouse Model of EBV Infection and Lymphoproliferative Disease
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  37. Combining T-cell-specific activation and in vivo gene delivery through CD3-targeted lentiviral vectors.
    Annika M Frank, Angela H Braun, Lea Scheib, Shiwani Agarwal, Irene C Schneider, Floriane Fusil, Séverine Perian, Ugur Sahin, Frederic B Thalheimer, Els Verhoeyen et al. · 2020 · PubMed Central
  38. Induction of tumor cell autosis by myxoma virus-infected CAR-T and TCR-T cells to overcome primary and acquired resistance
    Ningbo Zheng, Jing Fang, Gang Xue, Ziyu Wang, Xiaoyin Li, Mengshi Zhou, Guangxu Jin, Masmudur M. Rahman, Grant McFadden, Yong Lu · 2022 · Cancer Cell
  39. Chimeric antigen receptor T-cell therapy in glioblastoma: charging the T cells to fight
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  40. Context-aware synthetic biology by controller design: Engineering the mammalian cell
    Nika Shakiba, Ross D. Jones, Ron Weiss, Domitilla Del Vecchio · 2021 · Cell Systems
  41. Bispecific binder redirected lentiviral vector enables in vivo engineering of CAR-T cells
    Justin T. Huckaby, Elisa Landoni, Timothy M. Jacobs, Barbara Savoldo, Gianpietro Dotti, Samuel K. Lai · 2021 · Journal for ImmunoTherapy of Cancer
  42. CAR‐T cell therapy for lung cancer: Potential and perspective
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  43. Mimetic Heat Shock Protein Mediated Immune Process to Enhance Cancer Immunotherapy
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  44. Emerging Role of Extracellular Vesicles in Immune Regulation and Cancer Progression
    Sonam Mittal, Prachi Gupta, Pradeep Chaluvally–Raghavan, Sunila Pradeep · 2020 · Cancers
  45. Engineering CAR-T cells to activate small-molecule drugs in situ
    Thomas J. Gardner, J. Peter Lee, Christopher M. Bourne, Dinali Wijewarnasuriya, Nihar Kinarivala, Keifer G. Kurtz, Broderick C. Corless, Megan M. Dacek, Aaron Y. Chang, George Mo et al. · 2021 · Nature Chemical Biology
  46. Recent Advances in IL-13Rα2-Directed Cancer Immunotherapy
    Karin M. Knudson, SuJin Hwang, Mondona S. McCann, Bharat H. Joshi, Syed Rafat Husain, Raj K. Puri · 2022 · Frontiers in Immunology
  47. Computational Methods in Immunology and Vaccinology: Design and Development of Antibodies and Immunogens
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  48. Whole-body tracking of single cells via positron emission tomography
    Kyung Oh Jung, Tae Jin Kim, Jung Ho Yu, Siyeon Rhee, Wei Zhao, Byung Hang Ha, Kristy Red‐Horse, Sanjiv Sam Gambhir, Guillem Pratx · 2020 · Nature Biomedical Engineering
  49. Anti-αFR CAR-engineered NK-92 Cells Display Potent Cytotoxicity Against αFR-positive Ovarian Cancer
    Xiang Ao, Yu Pu Yang, Weiqiang Li, Yan Hong Tan, Wei Guo, Luoquan Ao, Xiao He, Xiaofeng Wu, Jian‐Chuan Xia, Xiang Ming Xu et al. · 2019 · Journal of Immunotherapy
  50. Synthetic multi-layer nanoparticles for CRISPR-Cas9 genome editing
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  51. The molecularly imprinted polymer essentials: curation of anticancer, ophthalmic, and projected gene therapy drug delivery systems
    Christian Antonio Tuwahatu, Chi Chung Yeung, Yun Wah Lam, Vellaisamy A. L. Roy · 2018 · Journal of Controlled Release
  52. Development of NKG2D-based chimeric antigen receptor-T cells for gastric cancer treatment
    Kelong Tao, Meng Qi He, Feng Tao, Guangen Xu, Minfeng Ye, Yuanyuan Zheng, Yaoqing Li · 2018 · Cancer Chemotherapy and Pharmacology
  53. Targeting senescent cells to attenuate cardiovascular disease progression
    Ping Song, Qiang Zhao, Ming‐Hui Zou · 2020 · Ageing Research Reviews
  54. Glycoengineering of Natural Killer Cells with CD22 Ligands for Enhanced Anticancer Immunotherapy
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  55. Inducing Endoplasmic Reticulum Stress to Expose Immunogens: A DNA Tetrahedron Nanoregulator for Enhanced Immunotherapy
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  56. Metabolic reprogramming by ex vivo glutamine inhibition endows CAR-T cells with less-differentiated phenotype and persistent antitumor activity
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  57. T-cell-engaging antibodies for the treatment of solid tumors: challenges and opportunities
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  58. Chimeric antigen receptor T-cell therapy for acute myeloid leukemia: how close to reality?
    Katherine D. Cummins, Saar I. Gill · 2019 · Haematologica
  59. Future Challenges in Cancer Resistance to Immunotherapy
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  60. Inducible Polarized Secretion of Exosomes in T and B Lymphocytes
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  61. In situ photothermal nano-vaccine based on tumor cell membrane-coated black phosphorus-Au for photo-immunotherapy of metastatic breast tumors
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  62. Escape from T-cell–targeting immunotherapies in acute myeloid leukemia
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  63. Role of myeloid cells in the immunosuppressive microenvironment in gliomas
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  64. Emerging nanomedicines for effective breast cancer immunotherapy
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  65. A Bibliometric and Knowledge-Map Analysis of CAR-T Cells From 2009 to 2021
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  66. Recent Advances in Solid Tumor CAR-T Cell Therapy: Driving Tumor Cells From Hero to Zero?
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  72. Chimeric antigen receptor T (CAR-T) cell immunotherapy for sarcomas: From mechanisms to potential clinical applications
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  73. Research Progress of Nanomedicine-Based Mild Photothermal Therapy in Tumor
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  74. Suppression of cytokine release syndrome during CAR-T-cell therapy via a subcutaneously injected interleukin-6-adsorbing hydrogel
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  75. Expanding access to CAR T cell therapies through local manufacturing
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  96. Extracellular Vesicles as an Advanced Delivery Biomaterial for Precision Cancer Immunotherapy
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