The DOI matches its Crossref record; 6 of the 6 references it cites were found in a registry or an index.
Golgi-derived PI ( 4 ) P-containing vesicles drive late steps of mitochondrial division
Abstract
PI(4)P regulates mitochondrial fission: Mitochondria are dynamic intracellular organelles, the shape and number of which are regulated by various cell-signaling pathways. Mitochondrial division is driven by the recruitment of a constricting guanosine triphosphatase protein at sites of contact with the endoplasmic reticulum, but other factors, including lysosomes, are also involved. Nagashima et al. now document an essential role for Golgi-derived vesicles bearing a specific lipid—phosphatidylinositol 4-phosphate, or PI(4)P—in the final steps of mitochondrial division. Disruption of PI(4)P production results in mitochondrial morphological defects indicative of an inability to complete fission. Science , this issue p. 1366
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Fiji: an open-source platform for biological-image analysis
Schindelin, J., Arganda-Carreras, I., Frise, E., Kaynig, V., Longair, M., Pietzsch, T., Preibisch, S., Rueden, C., Saalfeld, S., Schmid, B., et al. (2012) · Nature Methods · doi:10.1038/nmeth.2019 · Cited by 66,890
Mitochondrial dynamics: overview of molecular mechanisms
Tilokani, L., Nagashima, S., Paupe, V., & Prudent, J. (2018) · Essays in Biochemistry · doi:10.1042/ebc20170104 · Cited by 1,397
Self-citationAn Actin-Dependent Step in Mitochondrial Fission Mediated by the ER-Associated Formin INF2
Korobova, F., Ramabhadran, V., & Higgs, H. N. (2013) · Science · doi:10.1126/science.1228360 · Cited by 817
Multiple dynamin family members collaborate to drive mitochondrial division
Lee, J. E., Westrate, L. M., Wu, H., Page, C., & Voeltz, G. K. (2016) · Nature · doi:10.1038/nature20555 · Cited by 512
Newly born peroxisomes are a hybrid of mitochondrial and ER-derived pre-peroxisomes
Sugiura, A., Mattie, S., Prudent, J., & McBride, H. M. (2017) · Nature · doi:10.1038/nature21375 · Cited by 386
Self-citationDynamin-like protein 1 is involved in peroxisomal fission
Koch, A., Thiemann, M., Grabenbauer, M., Yoon, Y., McNiven, M. A., & Schrader, M. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m211761200 · Cited by 374
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Phosphoinositides as membrane organizers
Posor, Y., Jang, W., & Haucke, V. (2022) · Nature Reviews Molecular Cell Biology · doi:10.1038/s41580-022-00490-x · Cited by 469
Function and regulation of the divisome for mitochondrial fission
Kraus, F., Roy, K., Pucadyil, T. J., & Ryan, M. T. (2021) · Nature · doi:10.1038/s41586-021-03214-x · Cited by 445
Quality control of the mitochondrion
Ng, M. Y. W., Wai, T., & Simonsen, A. (2021) · Developmental Cell · doi:10.1016/j.devcel.2021.02.009 · Cited by 445
AMPK-dependent phosphorylation of MTFR1L regulates mitochondrial morphology
Tilokani, L., Russell, F. M., Hamilton, S., Virga, D. M., Segawa, M., Paupe, V., Gruszczyk, A. V., Protasoni, M., Tabara, L.-C., Johnson, M., et al. (2022) · Science Advances · doi:10.1126/sciadv.abo7956 · Cited by 60
Self-citationLin, T.-K., Lin, K.-J., Lin, K.-L., Liou, C.-W., Chen, S.-D., Chuang, Y.-C., Wang, P.-W., Chuang, J.-H., & Wang, T.-J. (2020) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2020.607392 · Cited by 19
Metadata
- Authors
- Nagashima, S., Tábara, L.-C., Tilokani, L., Paupe, V., Anand, H., Pogson, J. H., Zunino, R., McBride, H. M., & Prudent, J.
- Venue
- Science
- Published
- 2020-03-20
- Volume
- 367
- Issue
- 6484
- Pages
- 1366-1371
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W3011930227
- Cited by
- 233
- References
- 6
- FWCI
- 9.06
- Type
- journal article
- Language
- en
- Open access
- closed
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- Nagashima, S., Tábara, L.-C., Tilokani, L., Paupe, V., Anand, H., Pogson, J. H., Zunino, R., McBride, H. M., & Prudent, J. (2020). Golgi-derived PI ( 4 ) P-containing vesicles drive late steps of mitochondrial division. Science. https://doi.org/10.1126/science.aax6089
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