The DOI matches its Crossref record; 6 of the 6 references it cites were found in a registry or an index.
Specialized cutaneous Schwann cells initiate pain sensation
Open accessAbstract
A newly discovered cell type for pain perception: Pain has been thought to be initiated by activation of free nerve endings without end organs in the skin. In contrast to this paradigm, Abdo et al. discovered a previously unknown meshlike organ covering the skin that senses dangerous environmental stimuli (see the Perspective by Doan and Monk). This organ is built from specialized glial cells located in the epidermal-dermal border and is sufficient and required for initiation of mechanical pain transduction. Science , this issue p. 695 ; see also p. 641
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Molecular Architecture of the Mouse Nervous System
Zeisel, A., Hochgerner, H., Lönnerberg, P., Johnsson, A., Memic, F., van der Zwan, J., Häring, M., Braun, E., Borm, L. E., La Manno, G., et al. (2018) · Cell · doi:10.1016/j.cell.2018.06.021 · Cited by 2,552
Self-citationUnbiased classification of sensory neuron types by large-scale single-cell RNA sequencing
Usoskin, D., Furlan, A., Islam, S., Abdo, H., Lönnerberg, P., Lou, D., Hjerling-Leffler, J., Haeggström, J., Kharchenko, O., Kharchenko, P. V., et al. (2015) · Nature Neuroscience · doi:10.1038/nn.3881 · Cited by 2,136
Self-citationNeuropathic Pain: A Maladaptive Response of the Nervous System to Damage
Costigan, M., Scholz, J., & Woolf, C. J. (2009) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.051508.135531 · Cited by 2,025
Dorsal Horn Circuits for Persistent Mechanical Pain
Peirs, C., Williams, S.-P. G., Zhao, X., Walsh, C. E., Gedeon, J. Y., Cagle, N. E., Goldring, A. C., Hioki, H., Liu, Z., Marell, P. S., et al. (2015) · Neuron · doi:10.1016/j.neuron.2015.07.029 · Cited by 327
Identifying the pathways required for coping behaviours associated with sustained pain
Huang, T., Lin, S.-H., Malewicz, N. M., Zhang, Y., Zhang, Y., Goulding, M., LaMotte, R. H., & Ma, Q. (2019) · Nature · doi:10.1038/s41586-018-0793-8 · Cited by 264
Normal and abnormal coding of somatosensory stimuli causing pain
Prescott, S. A., Ma, Q., & De Koninck, Y. (2014) · Nature Neuroscience · doi:10.1038/nn.3629 · Cited by 210
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Neural circuits of interoception
Berntson, G. G., & Khalsa, S. S. (2021) · Trends in Neurosciences · doi:10.1016/j.tins.2020.09.011 · Cited by 419
“In this regard, these mechanosensitive Schwann cells express a PIEZO gene, encoding a mechanoreceptor similar to those discussed above, that may be relevant for their nociceptive mechanosensitivity [31].”
BackgroundJensen, T. S., Karlsson, P., Gylfadottir, S. S., Andersen, S. T., Bennett, D. L., Tankisi, H., Finnerup, N. B., Terkelsen, A. J., Khan, K., Themistocleous, A. C., et al. (2021) · Brain · doi:10.1093/brain/awab079 · Cited by 265
Circadian rhythmicity of body temperature and metabolism
Refinetti, R. (2020) · Temperature · doi:10.1080/23328940.2020.1743605 · Cited by 155
Metadata
- Authors
- Abdo, H., Calvo-Enrique, L., Lopez, J. M., Song, J., Zhang, M.-D., Usoskin, D., El Manira, A., Adameyko, I., Hjerling-Leffler, J., & Ernfors, P.
- Venue
- Science
- Published
- 2019-08-16
- Volume
- 365
- Issue
- 6454
- Pages
- 695-699
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2968074903
- Cited by
- 362
- References
- 6
- FWCI
- 24.72
- Type
- journal article
- Language
- en
- Open access
- green
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- Abdo, H., Calvo-Enrique, L., Lopez, J. M., Song, J., Zhang, M.-D., Usoskin, D., El Manira, A., Adameyko, I., Hjerling-Leffler, J., & Ernfors, P. (2019). Specialized cutaneous Schwann cells initiate pain sensation. Science. https://doi.org/10.1126/science.aax6452
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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