The DOI matches its Crossref record; 35 of the 35 references it cites were found in a registry or an index.
Tracking complex mixtures of chemicals in our changing environment
Open accessAbstract
Chemicals have improved our quality of life, but the resulting environmental pollution has the potential to cause detrimental effects on humans and the environment. People and biota are chronically exposed to thousands of chemicals from various environmental sources through multiple pathways. Environmental chemists and toxicologists have moved beyond detecting and quantifying single chemicals to characterizing complex mixtures of chemicals in indoor and outdoor environments and biological matrices. We highlight analytical and bioanalytical approaches to isolating, characterizing, and tracking groups of chemicals of concern in complex matrices. Techniques that combine chemical analysis and bioassays have the potential to facilitate the identification of mixtures of chemicals that pose a combined risk.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
The Lancet Commission on pollution and health
Landrigan, P. J., Fuller, R., Acosta, N. J. R., Adeyi, O., Arnold, R., Basu, N. (., Baldé, A. B., Bertollini, R., Bose-O'Reilly, S., Boufford, J. I., et al. (2018) · The Lancet · doi:10.1016/s0140-6736(17)32345-0 · Cited by 4,929
Identifying Small Molecules via High Resolution Mass Spectrometry: Communicating Confidence
Schymanski, E. L., Jeon, J., Gulde, R., Fenner, K., Ruff, M., Singer, H. P., & Hollender, J. (2014) · Environmental Science & Technology · doi:10.1021/es5002105 · Cited by 4,519
Self-citationPubChem 2019 update: improved access to chemical data
Kim, S., Chen, J., Cheng, T., Gindulyte, A., He, J., He, S., Li, Q., Shoemaker, B. A., Thiessen, P. A., Yu, B., et al. (2019) · Nucleic Acids Research · doi:10.1093/nar/gky1033 · Cited by 3,249
Petrie, B., Barden, R., & Kasprzyk-Hordern, B. (2015) · Water Research · doi:10.1016/j.watres.2014.08.053 · Cited by 2,614
Wild, C. P. (2005) · Cancer Epidemiology, Biomarkers & Prevention · doi:10.1158/1055-9965.epi-05-0456 · Cited by 2,562
Evaluating Pesticide Degradation in the Environment: Blind Spots and Emerging Opportunities
Fenner, K., Canonica, S., Wackett, L. P., & Elsner, M. (2013) · Science · doi:10.1126/science.1236281 · Cited by 1,163
The CompTox Chemistry Dashboard: a community data resource for environmental chemistry
Williams, A. J., Grulke, C. M., Edwards, J., McEachran, A. D., Mansouri, K., Baker, N. C., Patlewicz, G., Shah, I., Wambaugh, J. F., Judson, R. S., et al. (2017) · Journal of Cheminformatics · doi:10.1186/s13321-017-0247-6 · Cited by 1,143
Quantifying Synergy: A Systematic Review of Mixture Toxicity Studies within Environmental Toxicology
Cedergreen, N. (2014) · PLoS ONE · doi:10.1371/journal.pone.0096580 · Cited by 912
Rappaport, S. M., & Smith, M. T. (2010) · Science · doi:10.1126/science.1192603 · Cited by 846
Nontarget Screening with High Resolution Mass Spectrometry in the Environment: Ready to Go?
Hollender, J., Schymanski, E. L., Singer, H. P., & Ferguson, P. L. (2017) · Environmental Science & Technology · doi:10.1021/acs.est.7b02184 · Cited by 733
Self-citation
Cited by
A ubiquitous tire rubber–derived chemical induces acute mortality in coho salmon
Tian, Z., Zhao, H., Peter, K. T., Gonzalez, M., Wetzel, J., Wu, C., Hu, X., Prat, J., Mudrock, E., Hettinger, R., et al. (2021) · Science · doi:10.1126/science.abd6951 · Cited by 1,604
Outside the Safe Operating Space of the Planetary Boundary for Novel Entities
Persson, L., Carney Almroth, B. M., Collins, C. D., Cornell, S., de Wit, C. A., Diamond, M. L., Fantke, P., Hassellöv, M., MacLeod, M., Ryberg, M. W., et al. (2022) · Environmental Science & Technology · doi:10.1021/acs.est.1c04158 · Cited by 1,347
Emerging contaminants: A One Health perspective
Wang, F., Xiang, L., Sze-Yin Leung, K., Elsner, M., Zhang, Y., Guo, Y., Pan, B., Sun, H., An, T., Ying, G., et al. (2024) · The Innovation · doi:10.1016/j.xinn.2024.100612 · Cited by 639
Li, X., Shen, X., Jiang, W., Xi, Y., & Li, S. (2024) · Ecotoxicology and Environmental Safety · doi:10.1016/j.ecoenv.2024.116420 · Cited by 536
Sensors for Volatile Organic Compounds
Khatib, M., & Haick, H. (2022) · ACS Nano · doi:10.1021/acsnano.1c10827 · Cited by 533
Metadata
- Authors
- Escher, B. I., Stapleton, H. M., & Schymanski, E. L.
- Venue
- Science
- Published
- 2020-01-24
- Volume
- 367
- Issue
- 6476
- Pages
- 388-392
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W3002350232
- Cited by
- 767
- References
- 35
- FWCI
- 33.53
- Type
- journal article
- Language
- en
- Open access
- green
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Tracking complex mixtures of chemicals in our changing environment. https://app.cochat.ai/papers/10.1126/science.aay6636
- The paper
- Escher, B. I., Stapleton, H. M., & Schymanski, E. L. (2020). Tracking complex mixtures of chemicals in our changing environment. Science. https://doi.org/10.1126/science.aay6636
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.