Memories off the top of your head
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Cortical layer 1 has a special role in long-term memory
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Dendrites in layer 1 appear to mainly encode more abstract information compared with deeper layers where perceptual features are encoded.
“For example, dendrites in layer 1 appear to mainly encode more abstract information compared with deeper layers where perceptual features are encoded.241”
From Sleep—A brain-state serving systems memory consolidation (2023) · cites this paper as [241]
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Engrams and circuits crucial for systems consolidation of a memory
Kitamura, T., Ogawa, S. K., Roy, D. S., Okuyama, T., Morrissey, M. D., Smith, L. M., Redondo, R. L., & Tonegawa, S. (2017) · Science · doi:10.1126/science.aam6808 · Cited by 1,104 · see citing works
Development of the brain depends on the visual environment
BLAKEMORE, C., & COOPER, G. F. (1970) · Nature · doi:10.1038/228477a0 · Cited by 1,005 · see citing works
A cellular mechanism for cortical associations: an organizing principle for the cerebral cortex
Larkum, M. (2013) · Trends in Neurosciences · doi:10.1016/j.tins.2012.11.006 · Cited by 755 · see citing works
Self-citationThe Consolidation and Transformation of Memory
Dudai, Y., Karni, A., & Born, J. (2015) · Neuron · doi:10.1016/j.neuron.2015.09.004 · Cited by 741 · see citing works
Branch-specific dendritic Ca2+ spikes cause persistent synaptic plasticity
Cichon, J., & Gan, W. (2015) · Nature · doi:10.1038/nature14251 · Cited by 509 · see citing works
A Top-Down Cortical Circuit for Accurate Sensory Perception
Manita, S., Suzuki, T., Homma, C., Matsumoto, T., Odagawa, M., Yamada, K., Ota, K., Matsubara, C., Inutsuka, A., Sato, M., et al. (2015) · Neuron · doi:10.1016/j.neuron.2015.05.006 · Cited by 365 · see citing works
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Makino, H., & Komiyama, T. (2015) · Nature Neuroscience · doi:10.1038/nn.4061 · Cited by 318 · see citing works
Burst-dependent synaptic plasticity can coordinate learning in hierarchical circuits
Payeur, A., Guerguiev, J., Zenke, F., Richards, B. A., & Naud, R. (2021) · Nature Neuroscience · doi:10.1038/s41593-021-00857-x · Cited by 286 · see citing works
Higher-Order Thalamocortical Inputs Gate Synaptic Long-Term Potentiation via Disinhibition
Williams, L. E., & Holtmaat, A. J. D. G. (2018) · Neuron · doi:10.1016/j.neuron.2018.10.049 · Cited by 275 · see citing works
Sensory-evoked LTP driven by dendritic plateau potentials in vivo
Gambino, F., Pagès, S., Kehayas, V., Baptista, D., Tatti, R., Carleton, A., & Holtmaat, A. (2014) · Nature · doi:10.1038/nature13664 · Cited by 253 · see citing works
Learning-Related Plasticity in Dendrite-Targeting Layer 1 Interneurons
Abs, E., Poorthuis, R. B., Apelblat, D., Muhammad, K., Pardi, M. B., Enke, L., Kushinsky, D., Pu, D.-L., Eizinger, M. F., Conzelmann, K., et al. (2018) · Neuron · doi:10.1016/j.neuron.2018.09.001 · Cited by 212 · see citing works
Selective synaptic remodeling of amygdalocortical connections associated with fear memory
Yang, Y., Liu, D., Huang, W., Deng, J., Sun, Y.-G., Zuo, Y., & Poo, M. (2016) · Nature Neuroscience · doi:10.1038/nn.4370 · Cited by 187 · see citing works
Zhu, J. (2000) · The Journal of Physiology · doi:10.1111/j.1469-7793.2000.00571.x · Cited by 170 · see citing works
Perirhinal input to neocortical layer 1 controls learning
Doron, G., Shin, J. N., Takahashi, N., Drüke, M., Bocklisch, C., Skenderi, S., de Mont, L., Toumazou, M., Ledderose, J., Brecht, M., et al. (2020) · Science · doi:10.1126/science.aaz3136 · Cited by 160 · see citing works
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Schuman, B., Dellal, S., Prönneke, A., Machold, R., & Rudy, B. (2021) · Annual Review of Neuroscience · doi:10.1146/annurev-neuro-100520-012117 · Cited by 148 · see citing works
A thalamocortical top-down circuit for associative memory
Pardi, M. B., Vogenstahl, J., Dalmay, T., Spanò, T., Pu, D.-L., Naumann, L., Kretschmer, F., Sprekeler, H., & Letzkus, J. J. (2020) · Science · doi:10.1126/science.abc2399 · Cited by 103 · see citing works
Perirhinal input to neocortical layer 1 controls learningPreprint
Doron, G., Shin, J. N., Takahashi, N., et al. (2019) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/713883 · Cited by 46 · see citing works
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Sleep—A brain-state serving systems memory consolidation
Brodt, S., Inostroza, M., Niethard, N., & Born, J. (2023) · Neuron · doi:10.1016/j.neuron.2023.03.005 · Cited by 343 · see citing works
An integrative, multiscale view on neural theories of consciousness
Storm, J. F., Klink, P. C., Aru, J., Senn, W., Goebel, R., Pigorini, A., Avanzini, P., Vanduffel, W., Roelfsema, P. R., Massimini, M., et al. (2024) · Neuron · doi:10.1016/j.neuron.2024.02.004 · Cited by 114 · see citing works
“128,129 Furthermore, the observation that higher-order thalamo-cortical projections sustain the coupling between apical and basal dendrites has been proposed to explain the simultaneous completion of cortico-cortical and thalamo-cortical loops and therefore can serve as the mechanism for…”
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Aru, J., Drüke, M., Pikamäe, J., & Larkum, M. E. (2023) · Trends in Neurosciences · doi:10.1016/j.tins.2022.11.002 · Cited by 38 · see citing works
Self-citationContext-sensitive conscious interpretation and layer-5 pyramidal neurons in multistable perception
Bachmann, T. (2025) · Brain and Behavior · doi:10.1002/brb3.70393 · Cited by 3 · see citing works
- Authors
- Shin, J. N., Doron, G., & Larkum, M. E.
- Affiliations
- NYU Langone Health (US)
- Humboldt-Universität zu Berlin (DE)
- Corresponding author
- Doron, Guy
- Larkum, Matthew E.
- Venue
- Science
- Published
- 2021-10-29
- Volume
- 374
- Issue
- 6567
- Pages
- 538-539
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- PMC
- PMC7612398
- OpenAlex
- W3210999456
- Cited by
- 40
- References
- 17
- Citations by year
- 2026: 6 · 2025: 8 · 2024: 9 · 2023: 9 · 2022: 6 · 2021: 2
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Science (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Memory and Neural Mechanisms
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
- Life Sciences › Neuroscience › Cognitive Neuroscience › Memory Processes and Influences
- Keywords
- long-term memory, memory storage, neocortex
- MeSH terms
- Animals, Dendrites, Humans, Learning, Memory, Neural Inhibition, Neuronal Plasticity, Perception, Synapses, Pyramidal Cells, Neocortex
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