The DOI matches its Crossref record; 50 of the 50 references it cites were found in a registry or an index.
Immune correlates analysis of the mRNA-1273 COVID-19 vaccine efficacy clinical trial
Open accessPublished version of a preprint
Abstract
Antibody levels predict vaccine efficacy: Symptomatic COVID-19 infection can be prevented by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccines. A “correlate of protection” is a molecular biomarker to measure how much immunity is needed to fight infection and is key for successful global immunization programs. Gilbert et al . determined that antibodies are the correlate of protection in vaccinated individuals enrolled in the Moderna COVE phase 3 clinical trial (see the Perspective by Openshaw). By measuring binding and neutralizing antibodies against the viral spike protein, the authors found that the levels of both antibodies correlated with the degree of vaccine efficacy. The higher the antibody level, the greater the protection afforded by the messenger RNA (mRNA) vaccine. Antibody levels that predict mRNA vaccine efficacy can therefore be used to guide vaccine regimen modifications and support regulatory approvals for a broader spectrum of the population. —PNK
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The cited source says what the claim attributes to it.
In the citing paper
“Neutralizing antibodies in the sera of the participants will be assessed since they have been identified as one of the key parameters correlating with the observed protective efficacy of the first generation SARS-CoV-2 mRNA vaccine CVnCoV27, and a licensed COVID-19 mRNA vaccine28.”
From Efficacy of an unmodified bivalent mRNA vaccine against SARS-CoV-2 variants in female small animal models (2023) · cites this paper as [28]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Generalized Additive Models: An Introduction with R
Wood, S. N. (2017) · doi:10.1201/9781315370279 · Cited by 13,852
Efficacy and Safety of the mRNA-1273 SARS-CoV-2 Vaccine
Baden, L. R., El Sahly, H. M., Essink, B., Kotloff, K., Frey, S., Novak, R., Diemert, D., Spector, S. A., Rouphael, N., Creech, C. B., et al. (2021) · New England Journal of Medicine · doi:10.1056/nejmoa2035389 · Cited by 10,119
Self-citationCryo-EM structure of the 2019-nCoV spike in the prefusion conformation
Wrapp, D., Wang, N., Corbett, K. S., Goldsmith, J. A., Hsieh, C.-L., Abiona, O., Graham, B. S., & McLellan, J. S. (2020) · Science · doi:10.1126/science.abb2507 · Cited by 8,897
Sensitivity analysis in observational research: Introducing the E-value
VanderWeele, T. J., & Ding, P. (2017) · Annals of Internal Medicine · doi:10.7326/m16-2607 · Cited by 6,350
Structure of the SARS-CoV-2 spike receptor-binding domain bound to the ACE2 receptor
Lan, J., Ge, J., Yu, J., Shan, S., Zhou, H., Fan, S., Zhang, Q., Shi, X., Wang, Q., Zhang, L., et al. (2020) · Nature · doi:10.1038/s41586-020-2180-5 · Cited by 5,983
Self-citationVoysey, M., Clemens, S. A. C., Madhi, S. A., Weckx, L. Y., Folegatti, P. M., Aley, P. K., Angus, B., Baillie, V. L., Barnabas, S. L., Bhorat, Q. E., et al. (2021) · The Lancet · doi:10.1016/s0140-6736(20)32661-1 · Cited by 4,616
Khoury, D. S., Cromer, D., Reynaldi, A., Schlub, T. E., Wheatley, A. K., Juno, J. A., Subbarao, K., Kent, S. J., Triccas, J. A., & Davenport, M. P. (2021) · Nature Medicine · doi:10.1038/s41591-021-01377-8 · Cited by 3,742
An mRNA Vaccine against SARS-CoV-2 — Preliminary Report
Jackson, L. A., Anderson, E. J., Rouphael, N. G., Roberts, P. C., Makhene, M., Coler, R. N., McCullough, M. P., Chappell, J. D., Denison, M. R., Stevens, L. J., et al. (2020) · New England Journal of Medicine · doi:10.1056/nejmoa2022483 · Cited by 3,237
Self-citationCell entry mechanisms of SARS-CoV-2
Shang, J., Wan, Y., Luo, C., Ye, G., Geng, Q., Auerbach, A., & Li, F. (2020) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2003138117 · Cited by 3,142
Letko, M., Marzi, A., & Munster, V. (2020) · Nature Microbiology · doi:10.1038/s41564-020-0688-y · Cited by 3,109
Flagged first, then by citations
Research works printed but not linked: 5
- Moderna “Moderna Announces TeenCOVE Study of its COVID-19 Vaccine in Adolescents Meets Primary Endpoint and Plans to Submit Data to Regulators in Early June” (press release 25 May 2021); https://investors.modernatx.com/news-releases/news-release-details/moderna-announces-teencove-study-its-covid-19-vaccine.
- S. A. Plotkin P. B. Gilbert in Plotkin’s Vaccines S. A. Plotkin W. A. Orenstein P. A. Offit K. M. Edwards Eds. (Elsevier seventh ed. 2018) chap. 3.
- Regeneron “Phase 3 Prevention Trial Showed 81% Reduced Risk of Symptomatic SARS-CoV-2 Infections with Subcutaneous Administration of REGEN-COV™ (casirivimab with imdevimab)” (press release 12 April 2021); https://investor.regeneron.com/news-releases/news-release-details/phase-3-prevention-trial-showed-81-reduced-risk-symptomatic-sars.
- 10.1016/S0140-6736(21)02046-8 · DOI
- P. H. Westfall S. S. Young Resampling-Based Multiple Testing: Examples and Methods for P-Value Adjustment vol. 279 of Wiley Series in Probability and Statistics (Wiley 1993).
Cited by
Sorted by citations
Items 701–800 of 1,001
Ramos, L., Hernández-Porto, M., Palau, M. C., Alonso-Abreu, I., Reygosa, C., & Hernández‐Guerra, M. (2022) · Inflammatory Bowel Diseases · doi:10.1093/ibd/izac228 · Cited by 5
Pozo‐Balado, M. D. M., Bulnes‐Ramos, Á., Olivas‐Martínez, I., Garrido‐Rodríguez, V., Lozano, C., Álvarez‐Ríos, A. I., Sánchez-Sánchez, B., Sánchez-Bejarano, E., Maldonado-Calzado, I., Martín-Lara, J. M., et al. (2023) · Immunity & Ageing · doi:10.1186/s12979-023-00334-y · Cited by 5
Camacho, J., Albert, E., Álvarez‐Rodríguez, B., Rusu, L., Zulaica, J., Rodríguez-Moreno, A., Peiró, S., Geller, R., Navarro, D., & Giménez, E. (2023) · Journal of Medical Virology · doi:10.1002/jmv.28739 · Cited by 5
Ali, K. M., Rashid, P. M. A., Ali, K. M., Mahmood, K. I., & Rostam, H. M. (2024) · Central European Journal of Immunology · doi:10.5114/ceji.2024.136382 · Cited by 5
Moghnieh, R., Haddad, W., Jbeily, N., El-Hassan, S., Eid, S., Baba, H., Sily, M., Saber, Y., Abdallah, D., Bizri, A. R., et al. (2024) · PLoS ONE · doi:10.1371/journal.pone.0306457 · Cited by 5
Williams, D. E. (2022) · Scientific Reports · doi:10.1038/s41598-022-13748-3 · Cited by 5
Korosec, C. S., Farhang‐Sardroodi, S., Dick, D. W., Gholami, S., Ghaemi, M. S., Moyles, I. R., Craig, M., Ooi, H. K., & Heffernan, J. M. (2021) · medRxiv · doi:10.1101/2021.10.13.21264957 · Cited by 5
SARS-CoV-2 Vaccine in Dialysis Patients: Time for a Boost?
Krueger, K., Halasa, N., & Ison, M. G. (2021) · American Journal of Kidney Diseases · doi:10.1053/j.ajkd.2021.10.003 · Cited by 5
SARS-CoV-2 Omicron Neutralization After Heterologous Vaccine BoostingPreprint
Lyke, K. E., Atmar, R. L., Islas, C. P. D., Posavad, C. M., Szydlo, D. W., PaulChourdhury, R., Deming, M. E., Eaton, A., Jackson, L. A., Branche, A. R., et al. (2022) · medRxiv · doi:10.1101/2022.01.13.22268861 · Cited by 5
Self-citationAccelerated waning of the humoral response to SARS-CoV-2 vaccines in obesityPreprint
van der Klaauw, A. A., Horner, E. C., Pereyra-Gerber, P., Agrawal, U., Foster, W. S., Spencer, S., Vergese, B., Smith, M., Henning, E., Ramsay, I. D., et al. (2022) · medRxiv · doi:10.1101/2022.06.09.22276196 · Cited by 5
Touizer, E., Alrubayyi, A., Ford, R., Hussain, N., Gerber, P. P., Shum, H.-L., Rees-Spear, C., Muir, L., Gea‐Mallorquí, E., Kopycinski, J. T., et al. (2022) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2022.11.11.516111 · Cited by 5
Jiang, N., Wang, L., Hatta, M., Feng, C., Currier, M., Lin, X., Hossain, J., Cui, D., Mann, B. R., Kovacs, N. A., et al. (2023) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2023.01.08.523127 · Cited by 5
Pasquevich, K. A., Coria, L. M., Ceballos, A., Mazzitelli, B., Rodriguez, J. M., Demaría, A., Castro, C. P., Bruno, L. A., Saposnik, L. M., Salvatori, M., et al. (2023) · medRxiv · doi:10.1101/2023.01.10.22284009 · Cited by 5
The impact of vaccination frequency on COVID-19 public health outcomes: A model-based analysisPreprint
Stoddard, M., Lin, Y., Sarkar, S., Egeren, D. V., Mangalaganesh, S., Nolan, R. P., Rogers, M. S., Hather, G., White, L. F., & Chakravarty, A. (2023) · medRxiv · doi:10.1101/2023.01.26.23285076 · Cited by 5
Moliva, J. I., Andrew, S. F., Flynn, B. J., Wagner, D. A., Foulds, K. E., Gagné, M., Flebbe, D. R., Lamb, E., Provost, S. J., Marquez, J., et al. (2023) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2023.11.22.567930 · Cited by 5
Malewana, G. B. R., Stalls, V., May, A. J., Lu, X., Martinez, D. R., Schäfer, A., Li, D., Barr, M., Sutherland, L. L., Lee, E., et al. (2023) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2023.12.18.572191 · Cited by 5
Self-citationDudášová, J., Valenta, Z., & Sachs, J. R. (2024) · npj Vaccines · doi:10.1038/s41541-024-00937-6 · Cited by 4
Viral Dynamic Models During COVID ‐19: Are We Ready for the Next Pandemic?
Marc, A., Schiffer, J. T., Mentré, F., Perelson, A. S., & Guedj, J. (2025) · CPT Pharmacometrics & Systems Pharmacology · doi:10.1002/psp4.70055 · Cited by 4
Zambrana, J. V., Mellis, I. A., Shotwell, A., Maier, H. E., Saborio, Y., Barillas, C., López, R., Vásquez, G., Plazaola, M., Sánchez, N., et al. (2025) · Nature Communications · doi:10.1038/s41467-025-65235-8 · Cited by 7
Kapłonek, P., Bertera, H. L., Lee, D. W., Cizmeci, D., Yu, W., Wu, K., Chalkias, S., Wahid, R., Edwards, D., Alter, G., et al. (2026) · Infectious Diseases and Therapy · doi:10.1007/s40121-026-01303-w · Cited by 4
Enabling the evaluation of COVID-19 vaccines with correlates of protection
Marchant, A., Damme, P. V., Plotkin, S. A., Neels, P., Cassetti, M. C., Cramer, J. P., Gruber, M. F., Goldblatt, D., King, D., Hartig-Merkel, W., et al. (2023) · Biologicals · doi:10.1016/j.biologicals.2023.101723 · Cited by 6
Hwang, Y. H., Min, D., & Park, W. B. (2025) · Human Vaccines & Immunotherapeutics · doi:10.1080/21645515.2025.2473795 · Cited by 4
Atmar, R. L., Lyke, K. E., Posavad, C. M., Deming, M. E., Brady, R. C., Dobrzynski, D., Edupuganti, S., Mulligan, M. J., Rupp, R. E., Rostad, C. A., et al. (2025) · The Journal of Infectious Diseases · doi:10.1093/infdis/jiaf176 · Cited by 4
Self-citationIntrinsic immunogenicity is a major determinant of type-specific responses in SARS-CoV-2 infections
Quirk, G., Schoenle, M. V., Peyton, K. L., Uhrlaub, J. L., Lau, B., Liang, C.-Y., Burgess, J. L., Ellingson, K., Beitel, S. C., Romine, J. K., et al. (2025) · Nature Immunology · doi:10.1038/s41590-025-02162-2 · Cited by 5
Isogawa, M., Onodera, T., Ainai, A., Kotaki, R., Kanno, T., Saito, S., Tobiume, M., Tokunaga, K., Hara, M., Hirota, Y., et al. (2025) · Scientific Reports · doi:10.1038/s41598-025-00054-x · Cited by 5
Malewana, G. B. R., Stalls, V., May, A. J., Lu, X., Martinez, D. R., Schäfer, A., Li, D., Barr, M., Sutherland, L. L., Lee, E., et al. (2025) · Science Translational Medicine · doi:10.1126/scitranslmed.adn5651 · Cited by 10
Self-citationCaldera, F., Mogallapalli, H., Abusalim, A.-R. I., Farraye, F. A., & Hayney, M. S. (2025) · Clinical and Translational Gastroenterology · doi:10.14309/ctg.0000000000000924 · Cited by 4
Choi, S., Park, J. Y., Park, J. H., Kim, M., Kweon, O. J., & Chung, J.-W. (2022) · Annals of Laboratory Medicine · doi:10.3343/alm.2022.42.5.612 · Cited by 4
Terayama, Y., Tomita, N., Terada-Hirashima, J., Uemura, Y., Shimizu, Y., Takeuchi, J. S., Takamatsu, Y., Maeda, K., Mikami, A. S., Ujiie, M., et al. (2022) · Life · doi:10.3390/life12070966 · Cited by 4
Fernandes, E. R., Taminato, M., Apostólico, J. D. S., Gabrielonni, M. C., Lunardelli, V. A. S., Maricato, J. T., Andersen, M. L., Tufik, S., & Rosa, D. S. (2023) · Journal of Allergy and Clinical Immunology Global · doi:10.1016/j.jacig.2023.100083 · Cited by 5
Amellal, H., Assaid, N., Akarid, K., Maaroufi, A., Ezzikouri, S., & Sarih, M. (2023) · Vaccine X · doi:10.1016/j.jvacx.2023.100288 · Cited by 5
Dai, Y.-C., Lin, Y.-C., Ching, L. L., Tsai, J., Ishikawa, K. M., Tsai, W.-Y., Chen, J. J., Nerurkar, V. R., & Wang, W. (2023) · Microbiology Spectrum · doi:10.1128/spectrum.04081-22 · Cited by 4
Nurisyah, S., Iyori, M., Hasyim, A. A., Sakamoto, A., Hashimoto, H., Yamagata, K., Yamauchi, S., Amru, K., Zainal, K. H., Idris, I., et al. (2023) · Antibodies · doi:10.3390/antib12030060 · Cited by 4
O’Reilly, S. R., Kenny, G., Alrawahneh, T., Francois, N., Gu, L., Angeliadis, M., d’Autume, V. D. M., Leon, A. G., Feeney, E. R., Yousif, O., et al. (2023) · PLoS ONE · doi:10.1371/journal.pone.0294262 · Cited by 4
Hossaini, S., Keramat, F., Cheraghi, Z., Zareie, B., & Doosti‐Irani, A. (2023) · Journal of Research in Health Sciences · doi:10.34172/jrhs.2023.128 · Cited by 5
The fast-track development of COVID-19 vaccines
El‐Maradny, Y. A., Ramadan, A. A., Chavda, V. P., Balar, P. C., & Redwan, E. M. M. M. (2024) · Elsevier eBooks · doi:10.1016/b978-0-443-18564-9.00027-8 · Cited by 5
Budylowski, P., Chau, S., Banerjee, A., Guvenc, F., Samson, R., Hu, Q., Fiddes, L. K., Seifried, L. A., Chao, G. Y. C., Buchholz, M., et al. (2024) · The Journal of Immunology · doi:10.4049/jimmunol.2300320 · Cited by 4
Steenackers, K., Hanning, N., Bruckers, L. M., Desombere, I., Marchant, A., Ariën, K. K., Georges, D., Soentjens, P. H. P., D’Onofrio, V., Hites, M., et al. (2024) · Vaccine · doi:10.1016/j.vaccine.2024.07.018 · Cited by 4
Ashley, C. L., Bloul, M., Alca, S., Smith, L., Jin, W., Khoury, D. S., Counoupas, C., Davenport, M. P., Triccas, J. A., & Steain, M. C. (2024) · Journal of Virological Methods · doi:10.1016/j.jviromet.2024.115073 · Cited by 4
Dose-dependent serological profiling of AdCLD-CoV19-1 vaccine in adults
Lee, J. H., Shin, Y., Shin, K.-S., Park, J. Y., Kim, M. S., Park, Y.-S., Kim, W., Song, J. Y., Noh, J. Y., Cheong, H. J., et al. (2024) · mSphere · doi:10.1128/msphere.00998-24 · Cited by 4
McCormack, M. J., Scott, S., Logan, N., Raveendran, S., Newman, J., Santos, I. A., Bailey, D., Murcia, P. R., Thomson, E. C., Hosie, M. J., et al. (2025) · EBioMedicine · doi:10.1016/j.ebiom.2025.105760 · Cited by 4
Determinants of antibody levels and protection against omicron BQ.1/XBB breakthrough infection
Pérez, C. M., Ramírez‐Morros, A., Jiménez, A., Vidal, M., Pradenas, E., Barrios, D., Canyelles, M., Rubio, R., Cuamba, I., Izquierdo, L., et al. (2025) · Communications Medicine · doi:10.1038/s43856-025-00943-2 · Cited by 4
Madanat, L., Sager, M., O’Connor, D., Thapa, B., Aggarwal, N., Ghimire, B., Lauter, C. B., Maine, G. N., Sims, M. D., & Halalau, A. (2022) · International Journal of General Medicine · doi:10.2147/ijgm.s370080 · Cited by 4
DeGruttola, V. G., Goyal, R., Martin, N. K., & Wang, R. (2022) · Clinical Trials · doi:10.1177/17407745221111818 · Cited by 4
The Antibodies’ Response to SARS-CoV-2 Vaccination: 1-Year Follow Up
Nicolai, E., Tomassetti, F., Pelagalli, M., Sarubbi, S., Minieri, M., Nisini, A., Nuccetelli, M., Ciotti, M., Pieri, M., & Bernardini, S. (2023) · Biomedicines · doi:10.3390/biomedicines11102661 · Cited by 4
Subunit vaccine raised against the SARS‐CoV‐2 spike of Delta and Omicron variants
Sheng, F., Fan, Z., Zhou, K., Ma, S., Liang, M., Zhang, H., Xie, Y., Ha, Z., Jin, N., & Lu, H. (2023) · Journal of Medical Virology · doi:10.1002/jmv.29160 · Cited by 4
Augello, M., Wagenhäuser, I., Krone, M., Dauby, N., Ferrara, P., Sabbatucci, M., Ruță, S. M., Rezahosseini, O., Velikov, P., Gkrania‐Klotsas, E., et al. (2024) · Vaccine · doi:10.1016/j.vaccine.2024.126184 · Cited by 4
Overdevest, J. B., Irace, A. L., Mazzanti, V., Oh, E. J., Joseph, P. V., Devanand, D. P., Bitan, Z. C., Hod, E. A., Gudis, D. A., & Chiuzan, C. C. (2022) · PLoS ONE · doi:10.1371/journal.pone.0274611 · Cited by 4
Passenberg, M., Authorsen-Grudmann, R., Frey, A., Korth, J., Zmudzinski, J., Anastasiou, O. E., Möhlendick, B., Schmidt, H., Rashidi‐Alavijeh, J., & Willuweit, K. (2023) · Vaccines · doi:10.3390/vaccines11030572 · Cited by 4
Dulipsingh, L., Schaefer, E. J., Wakefield, D. B., Williams, K., Halilovic, A., & Crowell, R. E. (2023) · Heliyon · doi:10.1016/j.heliyon.2023.e17410 · Cited by 5
Leys, Y. E., Nwokocha, M., Walker, J. P., Butterfield, T. R., Frater, V., Thompson, T. K., Anderson, M., Cloherty, G., & Anzinger, J. J. (2022) · American Journal of Tropical Medicine and Hygiene · doi:10.4269/ajtmh.21-1128 · Cited by 5
Potts, K. G., Noyce, R. S., Gafuik, C., John, C. M., Todesco, H. M., de Heuvel, E., Favis, N. A., Kelly, M. M., Evans, D. H., & Mahoney, D. J. (2021) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2021.12.27.474282 · Cited by 5
Braeye, T., Catteau, L., Brondeel, R., van Loenhout, J. A. F., Proesmans, K., Cornelissen, L., Oyen, H. J. V., Stouten, V., Hubin, P., Billuart, M., et al. (2022) · SSRN Electronic Journal · doi:10.2139/ssrn.4000559 · Cited by 4
Moore, S. C., Kronsteiner, B., Longet, S., Adele, S., Deeks, A. S., Liu, C., Dejnirattisai, W., Silva-Reyes, L., Meardon, N., Faustini, S. E., et al. (2022) · SSRN Electronic Journal · doi:10.2139/ssrn.4180810 · Cited by 5
Leung, N., Cheng, S. M. S., Cohen, C. A., Martín-Sánchez, M., Au, N. Y. M., Luk, L. L. H., Tsang, L. C. H., Kwan, K. K. H., Chaothai, S., Fung, L. W. C., et al. (2022) · medRxiv · doi:10.1101/2022.08.25.22279158 · Cited by 4
Nilles, E. J., Aubin, M. D. S., Dumas, D., Duke, W., Etienne, M. C., Abdalla, G., Jarolı́m, P., Oasan, T., Garnier, S., Iihoshi, N., et al. (2022) · medRxiv · doi:10.1101/2022.10.24.22281399 · Cited by 4
Thiểm, V. Đ., Anh, Đ. Đ., Ha, V. H., Thom, N. V., Thang, T. C., Mateus, J., Carreño, J. M., Raghunandan, R., Huong, N. M., Mercer, L. D., et al. (2024) · Vaccine · doi:10.1016/j.vaccine.2024.126542 · Cited by 5
Bellows, R. A., Rahn, K. L., Hummel, W. C., Mayton, E. H., Berry, H. W., Ryan, E. P., Geiss, B. J., Dandy, D. S., & Henry, C. S. (2025) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2025.117640 · Cited by 3
Tseng, W.-P., Wu, J.-L., Lin, C., Kang, C., Chung, M., Lee, Y.-F., Chen, S., Lu, M., Ko, W., Lee, P., et al. (2025) · Vaccine · doi:10.1016/j.vaccine.2025.127383 · Cited by 3
Optimizing the breadth of SARS-CoV-2-neutralizing antibodies in vivo and in silico
Kuroda, D., Moriyama, S., Sasaki, H., & Takahashi, Y. (2025) · Human Vaccines & Immunotherapeutics · doi:10.1080/21645515.2025.2526873 · Cited by 3
Pediatric T cell and B cell responses to SARS-CoV-2 infection
Hills, L. B., Bhat, N., Hurst, J. H., Myers, A., Burke, T. W., McClain, M. T., Petzold, E., Rotta, A. T., Turner, N., Grifoni, A., et al. (2025) · JCI Insight · doi:10.1172/jci.insight.196032 · Cited by 3
Cheang, N. Y. Z., Yap, W. C., Tullett, K. M., Qian, X., Tan, P. S., Purushotorman, K., Tan, W. Y., Mah, S. Y. Y., MacAry, P. A., Tan, C. W., et al. (2026) · Journal of Clinical Investigation · doi:10.1172/jci195784 · Cited by 3
Pernikoff, S., Clurman, A. G., Rötepohl, M., Galanter, N., Bibby, M. G., Harris, E. D., Stevens‐Ayers, T., Xie, H., Ueda, M., Cheng, G., et al. (2025) · Open Forum Infectious Diseases · doi:10.1093/ofid/ofag005 · Cited by 3
Batra, H., Luo, S., Saunders, K. O., Higgins, J. S., Jian, F., Zhang, J., Kibria, M. G., Jonaid, G. M., Zhou, Q. J., Eaton, A., et al. (2026) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2537053123 · Cited by 4
Self-citationmRNA delivery of mosaic-8 pan-sarbecovirus RBD vaccines elicits distinct antibody epitope signatures
Cohen, A. A., Keeffe, J. R., Manasyan, L., Madireddy, I., Fils, A.-C. I. P., Dam, K.-M. A., Stober, H. E., Hills, R. A., Moon, W. J., Lin, P. J. C., et al. (2026) · Cell Reports · doi:10.1016/j.celrep.2026.117335 · Cited by 4
Protein-based vaccine as the booster dose for adults: evidence and beyond
Shang, L., & Cao, B. (2022) · The Lancet Infectious Diseases · doi:10.1016/s1473-3099(22)00447-9 · Cited by 3
Dawood, F. S., Couture, A., Zhang, X., Stockwell, M. S., Porucznik, C. A., Stanford, J. B., Hetrich, M. K., Veguilla, V., Thornburg, N. J., Heaney, C. D., et al. (2023) · Open Forum Infectious Diseases · doi:10.1093/ofid/ofad168 · Cited by 3
Chisty, Z., Li, D. D., Haile, M., Houston, H., DaSilva, J. C., Overton, R., Schuh, A. J., Haynie, J., Clemente, J., Branch, A., et al. (2024) · PLoS ONE · doi:10.1371/journal.pone.0301367 · Cited by 3
Roozen, G. V. T., Granger, A., van Binnendijk, R. S., den Hartog, G., Roestenberg, M., Visser, L. G., & Roukens, A. H. E. (2024) · Vaccine · doi:10.1016/j.vaccine.2024.06.060 · Cited by 3
Pather, S., Charpentier, N., van den Ouweland, F., Rizzi, R., Finlayson, A., Salisch, N. C., Muik, A., Lindemann, C., Khanim, R., Abdul-Jawad, S., et al. (2024) · Vaccine · doi:10.1016/j.vaccine.2024.126165 · Cited by 3
Ullah, I., Symmes, K., Keita, K., Zhu, L., Grunst, M. W., Li, W., Mothes, W., Kumar, P., & Uchil, P. D. (2024) · Vaccines · doi:10.3390/vaccines12091007 · Cited by 3
Muñoz, F. M., Beigi, R. H., Posavad, C. M., Kelly, C. W., Badell, M. L., Bunge, K. E., Mulligan, M. J., Parameswaran, L., Richardson, B. A., Olson‐Chen, C., et al. (2024) · The Pediatric Infectious Disease Journal · doi:10.1097/inf.0000000000004510 · Cited by 3
Self-citationmRNA-1273 COVID-19 vaccine induces CD4+ T-cell responses among solid organ transplant recipients
Girard, B., Figueroa, A. L., Rosa, S. C. D., McElrath, M. J., Azzi, J. R., Stolman, D., Siangphoe, U., de Windt, E., Miller, J. M., Das, R., et al. (2025) · Frontiers in Immunology · doi:10.3389/fimmu.2025.1505871 · Cited by 3
Self-citationMkhize, N. N., Zhang, B., Brackett, C., Elyanu, P., Tapley, A., Dadabhai, S. S., Hu, J., Do, B. T. N., Schuster, D. J., Heptinstall, J., et al. (2025) · Nature Communications · doi:10.1038/s41467-025-63948-4 · Cited by 3
Self-citationReduced immunogenicity of the mRNA vaccine BNT162b2 in patients with idiopathic pulmonary fibrosis
Karampitsakos, Τ., Παπαϊωάννου, Ο., Dimeas, I. E., Tsiri, P., Sotiropoulou, V., Tomos, I. P., Papanikolaou, I. C., Katsaras, M., Kirgou, P., Daniil, Z. D., et al. (2022) · ERJ Open Research · doi:10.1183/23120541.00082-2022 · Cited by 3
Correlates of protection via modeling
Schiffer, J. T. (2022) · Nature Computational Science · doi:10.1038/s43588-022-00221-4 · Cited by 3
Maron, J. S., Conroy, M. E., Naranbai, V., Samarakoon, U., Motazedi, T., Farmer, J. R., Freeman, E. E., Banerji, A., Bartsch, Y. C., Gregory, D. J., et al. (2022) · The Journal of Infectious Diseases · doi:10.1093/infdis/jiac107 · Cited by 3
Addala, S., Vissapragada, M., Aggunna, M., Mukala, N., Lanka, M., Gampa, S., Sodasani, M., Chintalapati, J., Kamidi, A., Veeranna, R. P., et al. (2022) · Vaccines · doi:10.3390/vaccines10060841 · Cited by 3
Population-Based Analysis of the Immunoglobulin G Response to Different COVID-19 Vaccines in Brazil
Paula, N. M., Conzentino, M. S., Gonçalves, A. C. A., da Silva, R., Weissheimer, K. V., Kluge, C. H. S., Marins, P. H. S. A., Camargo, H. S. C., Farias, L. R. P., Sant’Ana, T. P., et al. (2022) · Vaccines · doi:10.3390/vaccines11010021 · Cited by 4
Hueda-Zavaleta, M., de la Torre, J. C. G., Cáceres-DelAguila, J. A., Muro-Rojo, C., Cruz-Escurra, N. D. L., Copaja-Corzo, C., Aragón-Ayala, C. J., & Benites-Zapata, V. A. (2023) · Vaccines · doi:10.3390/vaccines11020447 · Cited by 3
Kobayashi, M., Mori, A., Onozawa, M., Tsukamoto, S., Senjo, H., Ishio, T., Yokoyama, E., Kanaya, M., Izumiyama, K., Saito, M., et al. (2023) · Annals of Hematology · doi:10.1007/s00277-023-05142-4 · Cited by 3
Berry, C., Pavot, V., Anosova, N. G., Kishko, M., Li, L., Tibbitts, T., Raillard, A., Gautheron, S., Cummings, S., Bangari, D. S., et al. (2023) · Communications Medicine · doi:10.1038/s43856-023-00302-z · Cited by 4
Dunn, D. T., Gilson, R. J. C., McCormack, S., & McCoy, L. E. (2023) · Vaccine · doi:10.1016/j.vaccine.2023.06.037 · Cited by 5
Bordry, N., Mamez, A., Fedeli, C., Cantero, C., Jaksic, C., Ustero, P., Rayroux, C., Berra, G., Portillo, V., Puntel, M., et al. (2023) · Vaccines · doi:10.3390/vaccines11081284 · Cited by 3
Dari, A., Solforosi, L., Roozendaal, R., Hoetelmans, R. M. W., Ruixo, J. J. P., & Boulton, M. (2023) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.123.001591 · Cited by 3
Rouphael, N., Branche, A. R., Diemert, D. J., Falsey, A. R., Losada, C., Baden, L. R., Frey, S. E., Whitaker, J. A., Little, S. J., Kamidani, S., et al. (2023) · The Journal of Infectious Diseases · doi:10.1093/infdis/jiad323 · Cited by 3
Self-citationDickson, A. M., Geerling, E., Stone, E. T., Hassert, M., Steffen, T. L., Makkena, T., Smither, M., Schwetye, K. E., Zhang, J., Georges, B., et al. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1188392 · Cited by 3
A Critical Assessment of COVID-19 Genomic Vaccines
Sabbah, D. A., Hajjo, R., & Sunoqrot, S. (2023) · Current Topics in Medicinal Chemistry · doi:10.2174/1568026623666230825094341 · Cited by 4
Hsu, F.-C., Pan, L., Huang, Y., Yang, C.-H., Shiu, M., & Lin, H. (2023) · The Journal of Infectious Diseases · doi:10.1093/infdis/jiad431 · Cited by 3
Risk factors and titers of COVID-19 infection in a longitudinal statewide seroepidemiology cohort
McQuade, E. T. R., Becker, L., Stroup, S. E., Khan, F., Shah, B., Brush, J. E., Goldsmith, G., Mullin, R., Guilliams, D., deFilippi, C. R., et al. (2023) · BMC Infectious Diseases · doi:10.1186/s12879-023-08670-6 · Cited by 3
Safitri, I. A., Sugijo, Y., Puspasari, F., Masduki, F. F., Ihsanawati, I., Giri-Rachman, E. A., Artarini, A., Tan, M. I., & Natalia, D. (2024) · Vaccine X · doi:10.1016/j.jvacx.2024.100443 · Cited by 4
Objectively measured peri-vaccination sleep does not predict COVID-19 breakthrough infection
Jaiswal, S. J., Gadaleta, M., Quer, G., Radin, J. M., Waalen, J., Ramos, E., Pandit, J. A., & Owens, R. L. (2024) · Scientific Reports · doi:10.1038/s41598-024-53743-4 · Cited by 3
Sieghart, D., Hana, C. A., Dürrschmid, C., Heinz, L. X., Haslacher, H., Zlesak, M., Piccini, G., Manenti, A., Montomoli, E., Jorda, A., et al. (2024) · Journal of Clinical Virology · doi:10.1016/j.jcv.2024.105661 · Cited by 3
Tai, C. G.-L., Haviland, M. J., Kissler, S. M., Lucia, R. M., MERSON, M. H., Maragakis, L. L., Ho, D. D., Anderson, D. J., DiFiori, J. P., Grubaugh, N. D., et al. (2024) · Journal of Medical Virology · doi:10.1002/jmv.29505 · Cited by 3
Study of the cellular and humoral immune responses to SARS-CoV-2 vaccination
Montmaneix-Engels, F., Dimeglio, C., Staes, L., Silva, I. D., Porcheron, M., Jougla, I., Hérin, F., & Izopet, J. (2024) · Heliyon · doi:10.1016/j.heliyon.2024.e29116 · Cited by 4
Costiniuk, C. T., Lee, T., Singer, J., Galipeau, Y., Arnold, C. R., Langlois, M., Needham, J., Jenabian, M.-A., Burchell, A. N., Samji, H., et al. (2024) · Vaccines · doi:10.3390/vaccines12050447 · Cited by 3
Lapadula, G., Mezzadri, L., Cascio, G. L., Antolini, L., Malandrin, S. M. I., Ranzani, A., Limonta, S., Cavallero, A., & Bonfanti, P. (2024) · Infection · doi:10.1007/s15010-024-02250-9 · Cited by 3
Antibody Titers and the Risk of Infection During the SARS-CoV-2 Omicron Phase in Bizen City, Japan
Kadowaki, T., Sasaki, A., Matsumoto, N., Mitsuhashi, T., Hagiya, H., Takao, S., & Yorifuji, T. (2024) · The Journal of Infectious Diseases · doi:10.1093/infdis/jiae207 · Cited by 6
Wolfe, D., Arangies, E., David, G. L., Armstrong, B., Scocca, T. Z., Fedler, J. K., Natarajan, R., Zhou, J., Jayashankar, L., Donis, R. O., et al. (2024) · Clinical Infectious Diseases · doi:10.1093/cid/ciae286 · Cited by 3
Self-citationKonuma, T., Hamatani‐Asakura, M., Nagai, E., Adachi, E., Kato, S., Isobe, M., Monna‐Oiwa, M., Takahashi, S., Yotsuyanagi, H., & Nannya, Y. (2024) · International Journal of Hematology · doi:10.1007/s12185-024-03802-3 · Cited by 3
Metadata
- Authors
- Gilbert, P. B., Montefiori, D. C., McDermott, A. B., Fong, Y., Benkeser, D., Deng, W., Zhou, H., Houchens, C. R., Martins, K., Jayashankar, L., Castellino, F., Flach, B., Lin, B. C., O’Connell, S., McDanal, C., Eaton, A., Sarzotti-Kelsoe, M., Lu, Y., Yu, C., Borate, B., van der Laan, L. W. P., Hejazi, N. S., Huynh, C., Miller, J., El Sahly, H. M., Baden, L. R., Baron, M., De La Cruz, L., Gay, C., Kalams, S., Kelley, C. F., Andrasik, M. P., Kublin, J. G., Corey, L., Neuzil, K. M., Carpp, L. N., Pajon, R., Follmann, D., Donis, R. O., Koup, R. A., Immune Assays Team§, Moderna, I. T., Coronavirus Vaccine Prevention Network (CoVPN)/Coronavirus Efficacy (COVE) Team§, & United States Government (USG)/CoVPN Biostatistics Team§
- Affiliations
- University of Washington (US)
- Duke University (US)
- National Institutes of Health (US)
- Fred Hutch Cancer Center (US)
- Emory University (US)
- Moderna Therapeutics (United States) (US)
- Biomedical Advanced Research and Development Authority (US)
- Department of Surgery and Duke Human Vaccine Institute, Duke University Medical Center, Durham, NC, USA.
- Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
- Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, TX, USA.
- Brigham and Women's Hospital (US)
- Palm Beach Research Center (US)
- Keystone Vitalink Research, Greenville, SC, USA.
- University of North Carolina at Chapel Hill (US)
- Vanderbilt University Medical Center (US)
- University of Maryland, Baltimore (US)
- Moderna, Inc., Cambridge, MA, USA.
- Biomedical Advanced Research and Development Authority, Washington, DC, USA.
- Corresponding author
- Gilbert, Peter B.
- Montefiori, David C.
- McDermott, Adrian B.
- Koup, Richard A.
- ORCID
- Gilbert, Peter B.
- Montefiori, David C.
- McDermott, Adrian B.
- Fong, Youyi
- Benkeser, David
- Deng, Weiping
- Houchens, Christopher R.
- Martins, Karen
- Jayashankar, Lakshmi
- Castellino, Flora
- Lin, Bob C.
- O’Connell, Sarah
- McDanal, Charlene
- Eaton, Amanda
- Lu, Yiwen
- Yu, Chenchen
- Borate, Bhavesh
- Hejazi, Nima S.
- Miller, Jacqueline
- El Sahly, Hana M.
- Baden, Lindsey R.
- Baron, Mira
- Gay, Cynthia
- Kalams, Spyros
- Kelley, Colleen F.
- Andrasik, Michele P.
- Kublin, James G.
- Corey, Lawrence
- Neuzil, Kathleen M.
- Carpp, Lindsay N.
- Follmann, Dean
- Donis, Ruben O.
- Koup, Richard A.
- Venue
- Science
- Published
- 2022-01-07
- Volume
- 375
- Issue
- 6576
- Pages
- 43-50
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- PMC
- PMC8366808
- OpenAlex
- W3217661335
- Cited by
- 1,137
- References
- 47
- Citations by year
- 2026: 65 · 2025: 114 · 2024: 197 · 2023: 278 · 2022: 412
- FWCI
- 123.36
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- cc-by
- Locations
- Science (publishedVersion, cc-by)
- medRxiv (acceptedVersion, cc-by-nc-nd)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- PubMed Central (submittedVersion, cc-by-nc-nd)
- Funders
- Wellcome Trust
- National Institutes of Health (1s10od028685-01, UL1TR002384)
- National Institute of Allergy and Infectious Diseases (S10AI174104, U01AI068635, UM1AI068614, UM1AI068635, UM1AI148575, UM1AI069476, R37AI054165, UM1AI148684, UM1AI069412)
- National Center for Advancing Translational Sciences
- Topics
- Health Sciences › Medicine › Infectious Diseases › SARS-CoV-2 and COVID-19 Research
- Health Sciences › Medicine › Infectious Diseases › COVID-19 Clinical Research Studies
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › vaccines and immunoinformatics approaches
- Keywords
- mRNA-1273 vaccine, COVID-19 vaccine efficacy, SARS-CoV-2, neutralizing antibodies, binding antibodies, correlates of protection, vaccine immunogenicity, vaccine approval
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review