Zonated mechanosensing by PIEZO1 controls liver regeneration

Piezo1 and Piezo2 Are Essential Components of Distinct Mechanically Activated Cation Channels

Coste, B., Mathur, J., Schmidt, M., Earley, T. J., Ranade, S., Petrus, M. J., Dubin, A. E., & Patapoutian, A. (2010) · Science · doi:10.1126/science.1193270 · Cited by 3,316 · see citing works

Liver Regeneration

Michalopoulos, G. K., & DeFrances, M. C. (1997) · Science · doi:10.1126/science.276.5309.60 · Cited by 2,828 · see citing works

The liver

Trefts, E., Gannon, M., & Wasserman, D. H. (2017) · Current Biology · doi:10.1016/j.cub.2017.09.019 · Cited by 1,452 · see citing works

Piezo1 integration of vascular architecture with physiological force

Li, J., Hou, B., Tumova, S., Muraki, K., Bruns, A. F., Ludlow, M. J., Sedó, A., Hyman, A. J., McKeown, L., Young, R. S., et al. (2014) · Nature · doi:10.1038/nature13701 · Cited by 1,210 · see citing works

Single-cell spatial reconstruction reveals global division of labour in the mammalian liver

Halpern, K. B., Shenhav, R., Matcovitch-Natan, O., Tóth, B., Lemze, D., Golan, M., Massasa, E. E., Baydatch, S., Landen, S., Moor, A. E., et al. (2017) · Nature · doi:10.1038/nature21065 · Cited by 1,059 · see citing works

Liver regeneration: biological and pathological mechanisms and implications

Michalopoulos, G. K., & Bhushan, B. (2021) · Nature Reviews Gastroenterology & Hepatology · doi:10.1038/s41575-020-0342-4 · Cited by 998 · see citing works

Spatial proteogenomics reveals distinct and evolutionarily conserved hepatic macrophage niches

Guilliams, M., Bonnardel, J., Haest, B., Vanderborght, B., Wagner, C., Remmerie, A., Bujko, A., Martens, L., Thoné, T., Browaeys, R., et al. (2022) · Cell · doi:10.1016/j.cell.2021.12.018 · Cited by 985 · see citing works

Inductive angiocrine signals from sinusoidal endothelium are required for liver regeneration

Ding, B., Nolan, D. J., Butler, J. M., James, D., Babazadeh, A. O., Rosenwaks, Z., Mittal, V., Kobayashi, H., Shido, K., Lyden, D. C., et al. (2010) · Nature · doi:10.1038/nature09493 · Cited by 837 · see citing works

Mechanical stretch triggers rapid epithelial cell division through Piezo1

Gudipaty, S. A., Lindblom, J., Loftus, P. D., Redd, M. J., Edes, K., Davey, C. F., Krishnegowda, V., & Rosenblatt, J. (2017) · Nature · doi:10.1038/nature21407 · Cited by 809 · see citing works

Mechanosensation of cyclical force by PIEZO1 is essential for innate immunity

Solis, A. G., Bielecki, P., Steach, H. R., Sharma, L., Harman, C. C. D., Yun, S., de Zoete, M. R., Warnock, J. N., To, S. D. F., York, A. G., et al. (2019) · Nature · doi:10.1038/s41586-019-1485-8 · Cited by 678 · see citing works

Self-renewing diploid Axin2+ cells fuel homeostatic renewal of the liver

Wang, B., Zhao, L., Fish, M., Logan, C. Y., & Nusse, R. (2015) · Nature · doi:10.1038/nature14863 · Cited by 674 · see citing works

Identification of a mesenchymal progenitor cell hierarchy in adipose tissue

Merrick, D., Sakers, A., Irgebay, Z., Okada, C., Calvert, C., Morley, M. P., Percec, I., & Seale, P. (2019) · Science · doi:10.1126/science.aav2501 · Cited by 664 · see citing works

Structure and mechanogating mechanism of the Piezo1 channel

Zhao, Q., Zhou, H., Chi, S., Wang, Y., Wang, J., Geng, J., Wu, K., Liu, W., Zhang, T., Dong, M.-Q., et al. (2018) · Nature · doi:10.1038/nature25743 · Cited by 628 · see citing works

Cholangiocytes act as facultative liver stem cells during impaired hepatocyte regeneration

Raven, A., Lu, W.-Y., Man, T. Y., Ferreira-Gonzalez, S., O’Duibhir, E., Dwyer, B. J., Thomson, J. P., Meehan, R. R., Bogorad, R., Koteliansky, V., et al. (2017) · Nature · doi:10.1038/nature23015 · Cited by 533 · see citing works

Hybrid Periportal Hepatocytes Regenerate the Injured Liver without Giving Rise to Cancer

Font-Burgada, J., Shalapour, S., Ramaswamy, S., Hsueh, B., Rossell, D., Umemura, A., Taniguchi, K., Nakagawa, H., Valasek, M. A., Ye, L., et al. (2015) · Cell · doi:10.1016/j.cell.2015.07.026 · Cited by 486 · see citing works

Spatial heterogeneity in the mammalian liver

Ben-Moshe, S., & Itzkovitz, S. (2019) · Nature Reviews Gastroenterology & Hepatology · doi:10.1038/s41575-019-0134-x · Cited by 485 · see citing works

Hypertrophy and Unconventional Cell Division of Hepatocytes Underlie Liver Regeneration

Miyaoka, Y., Ebato, K., Kato, H., Arakawa, S., Shimizu, S., & Miyajima, A. (2012) · Current Biology · doi:10.1016/j.cub.2012.05.016 · Cited by 461 · see citing works

Hepatostat: Liver regeneration and normal liver tissue maintenance

Michalopoulos, G. K. (2017) · Hepatology · doi:10.1002/hep.28988 · Cited by 444 · see citing works

Fate tracing of mature hepatocytes in mouse liver homeostasis and regeneration

Malato, Y., Naqvi, S., Schürmann, N., Ng, R., Wang, B., Zape, J., Kay, M. A., Grimm, D., & Willenbring, H. (2011) · Journal of Clinical Investigation · doi:10.1172/jci59261 · Cited by 434 · see citing works

Adult Hepatocytes Are Generated by Self-Duplication Rather than Stem Cell Differentiation

Yanger, K., Knigin, D., Zong, Y., Maggs, L., Gu, G., Akiyama, H., Pikarsky, E., & Stanger, B. Z. (2014) · Cell Stem Cell · doi:10.1016/j.stem.2014.06.003 · Cited by 426 · see citing works

The RSPO–LGR4/5–ZNRF3/RNF43 module controls liver zonation and size

Planas-Paz, L., Orsini, V., Boulter, L., Calabrese, D., Pikiolek, M., Nigsch, F., Xie, Y., Roma, G., Donovan, A., Marti, P., et al. (2016) · Nature Cell Biology · doi:10.1038/ncb3337 · Cited by 359 · see citing works

Endothelial Cell-Derived Angiopoietin-2 Controls Liver Regeneration as a Spatiotemporal Rheostat

Hu, J., Srivastava, K., Wieland, M. J., Runge, A., Mogler, C., Besemfelder, E., Terhardt, D., Vogel, M. J., Cao, L., Korn, C., et al. (2014) · Science · doi:10.1126/science.1244880 · Cited by 320 · see citing works

Liver homeostasis is maintained by midlobular zone 2 hepatocytes

Wei, Y., Wang, Y. G., Jia, Y., Li, L., Yoon, J., Zhang, S., Wang, Z., Zhang, Y., Zhu, M., Sharma, T., et al. (2021) · Science · doi:10.1126/science.abb1625 · Cited by 292 · see citing works

Enhancing the precision of genetic lineage tracing using dual recombinases

He, L., Li, Y., Li, Y., Pu, W., Huang, X., Tian, X., Wang, Y., Zhang, H., Liu, Q., Zhang, L., et al. (2017) · Nature Medicine · doi:10.1038/nm.4437 · Cited by 273 · see citing works

Matrix viscoelasticity promotes liver cancer progression in the pre-cirrhotic liver

Fan, W., Adebowale, K., Váncza, L., Li, Y., Rabbi, M. F., Kunimoto, K., Chen, D., Mozes, G., Chiu, D. K.-C., Li, Y., et al. (2024) · Nature · doi:10.1038/s41586-023-06991-9 · Cited by 263 · see citing works

Proliferation tracing reveals regional hepatocyte generation in liver homeostasis and repair

He, L., Pu, W., Liu, X., Zhang, Z., Han, M., Li, Y., Huang, X., Han, X., Li, Y., Liu, K., et al. (2021) · Science · doi:10.1126/science.abc4346 · Cited by 261 · see citing works

Common PIEZO1 Allele in African Populations Causes RBC Dehydration and Attenuates Plasmodium Infection

Ma, S., Cahalan, S., LaMonte, G., Grubaugh, N. D., Zeng, W., Murthy, S. E., Paytas, E., Gamini, R., Lukacs, V., Whitwam, T., et al. (2018) · Cell · doi:10.1016/j.cell.2018.02.047 · Cited by 250 · see citing works

Cellular Homeostasis and Repair in the Mammalian Liver

Stanger, B. Z. (2015) · Annual Review of Physiology · doi:10.1146/annurev-physiol-021113-170255 · Cited by 248 · see citing works

Broad Distribution of Hepatocyte Proliferation in Liver Homeostasis and Regeneration

Chen, F., Jimenez, R. J., Sharma, K., Luu, H. Y., Hsu, B. Y., Ravindranathan, A., Stohr, B. A., & Willenbring, H. (2020) · Cell Stem Cell · doi:10.1016/j.stem.2019.11.001 · Cited by 236 · see citing works

The spatiotemporal program of zonal liver regeneration following acute injury

Ben-Moshe, S., Veg, T., Manco, R., Dan, S., Papinutti, D., Lifshitz, A., Kolodziejczyk, A. A., Bahar Halpern, K., Elinav, E., & Itzkovitz, S. (2022) · Cell Stem Cell · doi:10.1016/j.stem.2022.04.008 · Cited by 224 · see citing works

Spatial sorting enables comprehensive characterization of liver zonation

Ben-Moshe, S., Shapira, Y., Moor, A. E., Manco, R., Veg, T., Bahar Halpern, K., & Itzkovitz, S. (2019) · Nature Metabolism · doi:10.1038/s42255-019-0109-9 · Cited by 205 · see citing works

Hippo signalling in the liver: role in development, regeneration and disease

Russell, J. O., & Camargo, F. D. (2022) · Nature Reviews Gastroenterology & Hepatology · doi:10.1038/s41575-021-00571-w · Cited by 205 · see citing works

Spatial sorting enables comprehensive characterization of liver zonation

Ben-Moshe, S., Shapira, Y., Moor, A. E., Halpern, K. B., & Itzkovitz, S. (2019) · doi:10.1101/529784 · Cited by 205 · see citing works

Passive coupling of membrane tension and cell volume during active response of cells to osmosis

Roffay, C., Molinard, G., Kim, K., Urbanska, M., Andrade, V., Barbarasa, V., Nowak, P., Mercier, V., García‐Calvo, J., Matile, S., et al. (2021) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2103228118 · Cited by 202 · see citing works

Spatial Transcriptomics to define transcriptional patterns of zonation and structural components in the mouse liver

Hildebrandt, F., Andersson, A., Saarenpää, S., Larsson, L., Hul, N. V., Kanatani, S., Masek, J., Ellis, E. C. S., Barragán, A., Mollbrink, A., et al. (2021) · Nature Communications · doi:10.1038/s41467-021-27354-w · Cited by 195 · see citing works

Mechanosensing by β1 integrin induces angiocrine signals for liver growth and survival

Lorenz, L., Axnick, J., Buschmann, T., Henning, C., Urner, S., Fang, S., Nurmi, H., Eichhorst, N., Holtmeier, R., Bódis, K., et al. (2018) · Nature · doi:10.1038/s41586-018-0522-3 · Cited by 171 · see citing works

Adipocyte Piezo1 mediates obesogenic adipogenesis through the FGF1/FGFR1 signaling pathway in mice

Wang, S., Cao, S., Arhatte, M., Li, D., Shi, Y. X., Kurz, S., Hu, J., Wang, L., Shao, J., Atzberger, A., et al. (2020) · Nature Communications · doi:10.1038/s41467-020-16026-w · Cited by 152 · see citing works

Epithelial Plasticity during Liver Injury and Regeneration

Gadd, V. L., Aleksieva, N., & Forbes, S. J. (2020) · Cell Stem Cell · doi:10.1016/j.stem.2020.08.016 · Cited by 142 · see citing works

Multimodal decoding of human liver regeneration

Matchett, K. P., Wilson-Kanamori, J. R., Portman, J. R., Kapourani, C. A., Fercoq, F., May, S., Zajdel, E., Beltran, M., Sutherland, E. F., Mackey, J. B. G., et al. (2024) · Nature · doi:10.1038/s41586-024-07376-2 · Cited by 140 · see citing works

Circulating Levels of Soluble Dipeptidyl Peptidase-4 Are Dissociated from Inflammation and Induced by Enzymatic DPP4 Inhibition

Varin, E. M., Mulvihill, E. E., Beaudry, J. L., Pujadas, G., Fuchs, S., Tanti, J., Fazio, S., Kaur, K., Cao, X., Baggio, L. L., et al. (2018) · Cell Metabolism · doi:10.1016/j.cmet.2018.10.001 · Cited by 138 · see citing works

Mfsd2a+ hepatocytes repopulate the liver during injury and regeneration

Pu, W., Zhang, H., Huang, X., Tian, X., He, L., Wang, Y., Zhang, L., Liu, Q., Li, Y., Li, Y., et al. (2016) · Nature Communications · doi:10.1038/ncomms13369 · Cited by 136 · see citing works

Untitled work

(2001) · PubMed · Cited by 136 · see citing works

PIEZO-dependent mechanosensing is essential for intestinal stem cell fate decision and maintenance

Baghdadi, M. B., Houtekamer, R. M., Perrin, L., Rao‐Bhatia, A., Whelen, M., Decker, L., Bergert, M., Gonzalez, C. P., Bouras, R., Gropplero, G., et al. (2024) · Science · doi:10.1126/science.adj7615 · Cited by 115 · see citing works

Spatiotemporal Metabolic Liver Zonation and Consequences on Pathophysiology

Martini, T., Naef, F., & Tchorz, J. S. (2023) · Annual Review of Pathology: Mechanisms of Disease · doi:10.1146/annurev-pathmechdis-031521-024831 · Cited by 113 · see citing works

Hepatic stellate cells control liver zonation, size and functions via R-spondin 3

Sugimoto, A., Saito, Y., Wang, G., Sun, Q., Yin, C., Lee, K. H., Geng, Y., Rajbhandari, P., Hernandez, C., Steffani, M., et al. (2025) · Nature · doi:10.1038/s41586-025-08677-w · Cited by 110 · see citing works

Cell tension and mechanical regulation of cell volume

Gonzalez, N. P., Tao, J., Rochman, N. D., Vig, D., Chiu, E., Wirtz, D., & Sun, S. X. (2018) · Molecular Biology of the Cell · doi:10.1091/mbc.e18-04-0213 · Cited by 87 · see citing works

Regeneration Defects in Yap and Taz Mutant Mouse Livers Are Caused by Bile Duct Disruption and Cholestasis

Verboven, E., Moya, I. M., Sansores-Garcia, L., Xie, J., Hillen, H., Kowalczyk, W., Vella, G., Verhulst, S., Castaldo, S. A., Algueró-Nadal, A., et al. (2021) · Gastroenterology · doi:10.1053/j.gastro.2020.10.035 · Cited by 87 · see citing works

The mechanosensitive ion channel PIEZO1 is expressed in tendons and regulates physical performance

Nakamichi, R., Ma, S., Nonoyama, T., Chiba, T., Kurimoto, R., Ohzono, H., Olmer, M., Shukunami, C., Fuku, N., Wang, G., et al. (2022) · Science Translational Medicine · doi:10.1126/scitranslmed.abj5557 · Cited by 87 · see citing works

ZNRF3 and RNF43 cooperate to safeguard metabolic liver zonation and hepatocyte proliferation

Sun, T., Annunziato, S., Bergling, S., Sheng, C., Orsini, V., Forcella, P., Pikiolek, M., Kancherla, V., Holwerda, S., Imanci, D., et al. (2021) · Cell Stem Cell · doi:10.1016/j.stem.2021.05.013 · Cited by 84 · see citing works

Mechanotransduction in the pathogenesis of non-alcoholic fatty liver disease

Mitten, E. K., & Baffy, G. (2022) · Journal of Hepatology · doi:10.1016/j.jhep.2022.08.028 · Cited by 80 · see citing works

A spatiotemporal atlas of mouse liver homeostasis and regeneration

Xu, J., Guo, P., Hao, S., Shangguan, S., Shi, Q., Volpe, G., Huang, K., Zuo, J., An, J., Yuan, Y., et al. (2024) · Nature Genetics · doi:10.1038/s41588-024-01709-7 · Cited by 75 · see citing works

PIEZO1 mediates periostin+ myofibroblast activation and pulmonary fibrosis in mice

Xu, L., Li, T., Cao, Y., He, Y., Shao, Z., Liu, S., Wang, B., Su, A., Tian, H., Li, Y., et al. (2025) · Journal of Clinical Investigation · doi:10.1172/jci184158 · Cited by 65 · see citing works

Enteric neuronal Piezo1 maintains mechanical and immunological homeostasis by sensing force

Xie, Z., Rose, L., Feng, J., Zhao, Y., Lu, Y., Kane, H., Hibberd, T. J., Hu, X., Wang, Z., Zang, K., et al. (2025) · Cell · doi:10.1016/j.cell.2025.02.031 · Cited by 65 · see citing works

Metabolic inflexibility promotes mitochondrial health during liver regeneration

Wang, X., Menezes, C. J., Jia, Y., Xiao, Y., Venigalla, S. S. K., Cai, F., Hsieh, M.-H., Gu, W., Du, L., Sudderth, J., et al. (2024) · Science · doi:10.1126/science.adj4301 · Cited by 64 · see citing works

Dpp4+ interstitial progenitor cells contribute to basal and high fat diet-induced adipogenesis

Stefkovich, M. L., Traynor, S., Cheng, L., Merrick, D., & Seale, P. (2021) · Molecular Metabolism · doi:10.1016/j.molmet.2021.101357 · Cited by 56 · see citing works

Macrophages harness hepatocyte glutamate to boost liver regeneration

Rigual, M. D. M., Angulo-Aguado, M., Zagorac, S., Álvarez-Díaz, R., Benítez-Mondéjar, M., Yi, F., Martínez-Garay, C., Santos-de-Frutos, K., Kim, E., Campos-Olivas, R., et al. (2025) · Nature · doi:10.1038/s41586-025-08778-6 · Cited by 53 · see citing works

Viscoelastic Multiscale Mechanical Indexes for Assessing Liver Fibrosis and Treatment Outcomes

Chang, Z., Zhang, L., Hang, J.-T., Liu, W., & Xu, G. (2023) · Nano Letters · doi:10.1021/acs.nanolett.3c03341 · Cited by 45 · see citing works

NIBR-LTSi is a selective LATS kinase inhibitor activating YAP signaling and expanding tissue stem cells in vitro and in vivo

Namoto, K., Baader, C., Orsini, V., Landshammer, A., Breuer, E., Dinh, K. T., Ungricht, R., Pikiolek, M., Laurent, S., Lu, B., et al. (2024) · Cell stem cell · doi:10.1016/j.stem.2024.03.003 · Cited by 42 · see citing works

Region-specific cellular and molecular basis of liver regeneration after acute pericentral injury.

Wang, S., Wang, X., Shan, Y., Tan, Z., Su, Y., Cao, Y., Wang, S., Dong, J., Gu, J., & Wang, Y. (2024) · Cell Stem Cell · doi:10.1016/j.stem.2024.01.013 · Cited by 40 · see citing works

Spatial metabolic gradients in the liver and small intestine

Samarah, L. Z., Zheng, C., Xing, X., Lee, W. D., Afriat, A., Chitra, U., MacArthur, M. R., Lu, W., Jankowski, C. S. R., Ma, C., et al. (2025) · Nature · doi:10.1038/s41586-025-09616-5 · Cited by 40 · see citing works

IGFBP2 expressing midlobular hepatocytes preferentially contribute to liver homeostasis and regeneration

Lin, Y.-H., Wei, Y., Zeng, Q., Wang, Y., Pagani, C. A., Li, L., Zhu, M., Wang, Z., Hsieh, M.-H., Corbitt, N., et al. (2023) · Cell Stem Cell · doi:10.1016/j.stem.2023.04.007 · Cited by 33 · see citing works

Distinct hepatocyte identities in liver homeostasis and regeneration

Chen, F., Schönberger, K., & Tchorz, J. S. (2023) · JHEP Reports · doi:10.1016/j.jhepr.2023.100779 · Cited by 30 · see citing works

Direct mechanical exposure initiates hepatocyte proliferation

Li, W., Wu, Y. C., Hu, W., Zhou, J., Shu, X., Zhang, X., Zhang, Z., Wu, H. C., Du, Y. M., Lü, D., et al. (2023) · JHEP Reports · doi:10.1016/j.jhepr.2023.100905 · Cited by 28 · see citing works

Heterogeneity of hepatocyte dynamics restores liver architecture after chemical, physical or viral damage

Ruz‐Maldonado, I., González, J. T., Zhang, H., Sun, J., Bort, A., Kabir, I., Kibbey, R. G., Suárez, Y., Greif, D. M., & Fernandez-Hernando, C. F. (2024) · Nature Communications · doi:10.1038/s41467-024-45439-0 · Cited by 26 · see citing works

Zonation, Zonation, Zonation: The Real Estate of the Liver

Yasaka, T. M., Kim, C., Meadows, V., & Monga, S. P. (2025) · Annual Review of Pathology Mechanisms of Disease · doi:10.1146/annurev-pathmechdis-042624-091820 · Cited by 21 · see citing works

Stretch-induced hepatic endothelial mechanocrine promotes hepatocyte proliferation

Wu, Y., Li, L., Li, W., Li, N., Zhang, X., Zheng, L., Zhong, S., Lü, S., Shu, X., Zhou, J. R., et al. (2024) · Hepatology · doi:10.1097/hep.0000000000001082 · Cited by 19 · see citing works

PIEZO channels link mechanical forces to uterine contractions in parturition

Zhang, Y., Kini, S. A., Mishkanian, S. A., et al. (2025) · Science · doi:10.1126/science.ady3045 · Cited by 16 · see citing works

Endothelial force sensing signals to parenchymal cells to regulate bile and plasma lipids

Lichtenstein, L., Cheng, C. W., Bajarwan, M., Evans, E. L., Gaunt, H. J., Bartoli, F., Chuntharpursat-Bon, E., Patel, S., Konstantinou, C., Futers, T. S., et al. (2024) · Science Advances · doi:10.1126/sciadv.adq3075 · Cited by 15 · see citing works

Spatial-temporal proliferation of hepatocytes during pregnancy revealed by genetic lineage tracing

He, S., Guo, Z., Zhou, M., Wang, H., Zhang, Z., Shi, M., Li, X., Yang, X., & He, L. (2023) · Cell stem cell · doi:10.1016/j.stem.2023.09.002 · Cited by 15 · see citing works

Generation of Piezo1‐CreER transgenic mice for visualization and lineage tracing of mechanical force responsive cells in vivo

Li, X., Zhang, Z., Han, M., et al. (2022) · genesis · doi:10.1002/dvg.23476 · Cited by 13 · see citing works

Self-maintenance of zonal hepatocytes during adult homeostasis and their complex plasticity upon distinct liver injuries

Ang, C. H., Arandjelovic, P., Cheng, J., Yang, J., Guo, F., Yu, Y., Nelameham, S., Whitehead, L. W., Li, J., Silver, D. L., et al. (2024) · Cell Reports · doi:10.1016/j.celrep.2024.115093 · Cited by 10 · see citing works

EGFR-mediated crosstalk between vascular endothelial cells and hepatocytes promotes Piezo1-dependent liver regeneration

Hu, Y., Du, G., Li, C., Wang, R., Liu, J., Wang, Y., & Dong, J. (2025) · Genes & Diseases · doi:10.1016/j.gendis.2024.101321 · Cited by 7 · see citing works

The mechanics of liver regeneration.

Maeso-Díaz, R., & Diehl, A. M. (2026) · Science · doi:10.1126/science.aei7784

PIEZO1 senses the mechanics of liver regeneration

Kotsiliti, E. (2026) · Nature Reviews Gastroenterology & Hepatology · doi:10.1038/s41575-026-01237-1

Cellular senescence is associated with age-related loss of liver zonation and hepatocyte functionPreprint

Laux, L., Aristel, A., Ali, S., Lande, K., Li, M., Evensen, K. G., Havas, A. P., Miao, Z., Zhang, J., Peters, S., et al. (2026) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2026.08.08.743614

Niche-dependent immunometabolic regulation of tissue repair and regeneration

Xie, X., Zeng, L., Chi, Z.-X., & Wang, D. (2026) · Immunity & Inflammation · doi:10.1007/s44466-026-00052-2

Liver regeneration governed by zonated PIEZO1 mechanotransduction

Xie, L., Zhang, C., Wei, Y., et al. (2026) · Cell Regeneration · doi:10.1186/s13619-026-00305-w