Cited by 59Ubiquitin and proteasome pathwaysGenomics and Chromatin DynamicsDNA Repair Mechanisms

SUMOylation of the Transcriptional Co-Repressor KAP1 Is Regulated by the Serine and Threonine Phosphatase PP1

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Li, Xu, Lin, H. Helen, Chen, Hanqing, Xu, Xingzhi, Shih, Hsiu-Ming, Ann, David K.·2010·Science Signaling

Abstract

Two isoforms of protein phosphatase 1 coordinate the recovery of cells from genotoxic stress.

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Crossref · 10.1126/scisignal.2000781

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Authors
Li, X., Lin, H. H., Chen, H., Xu, X., Shih, H.-M., & Ann, D. K.
Affiliations
  • University of Southern California (US)
  • City Of Hope National Medical Center (US)
  • Capital Normal University (CN)
  • Institute of Biomedical Sciences, Academia Sinica (TW)
Corresponding author
Ann, David K.
Venue
Science Signaling
Published
2010-04-27
Volume
3
Issue
119
Pages
ra32-ra32
ISSN
  • 1937-9145 (ISSN-L)
  • 1945-0877
OpenAlex
W2160256607
Cited by
59
References
52
Citations by year
2026: 3 · 2025: 3 · 2023: 3 · 2021: 1 · 2020: 1 · 2019: 2 · 2018: 4 · 2017: 1 · 2016: 4 · 2015: 9 · 2014: 7 · 2013: 6 · 2012: 6
FWCI
2.74
Type
journal article
Language
en
Open access
Locations
  • Science Signaling (publishedVersion)
  • PubMed (publishedVersion)
  • PubMed Central (acceptedVersion)
Funders
  • National Cancer Institute (P30CA033572)
  • National Institute of Dental and Craniofacial Research (R01 DE 10742, R01DE010742, R01DE014183, R01-DE-14183)
Topics
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Ubiquitin and proteasome pathways
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Genomics and Chromatin Dynamics
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › DNA Repair Mechanisms
Keywords
KAP1, SUMOylation, protein phosphatase 1, PP1α, ATM, DNA double-strand breaks, genotoxic stress, corepressors, dephosphorylation, transcriptional regulation
MeSH terms
Tripartite Motif-Containing Protein 28, Binding Sites, Cell Cycle, DNA Damage, Humans, Kinetics, Phosphoprotein Phosphatases, Phosphorylation, Promoter Regions, Genetic, Repressor Proteins, Small Ubiquitin-Related Modifier Proteins, Cell Line, Tumor, Immunoprecipitation, Gene Knockdown Techniques

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