Controlling the Fate of NIK: A Central Stage in Noncanonical NF-κB Signaling
Open accessAbstract
A component of the IκB kinase complex mediates feedback inhibition of the kinase NIK.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
There was evidence for noncanonical NF-κB activation in CIN-high cells as revealed by lower levels of p100, a trend toward higher ratios of p52 and phosphorylated p100 relative to total p100, and lower levels of TRAF2.
“We found evidence for noncanonical NF-κB activation in CIN-high cells as revealed by lower levels of the precursor protein, p100, a trend toward higher ratios of p52 and phosphorylated p100 relative to total p100, as well as lower levels of the noncanonical NF-κB pathway inhibitor, TRAF231”
From Chromosomal instability drives metastasis through a cytosolic DNA response (2018) · cites this paper as [31]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
Shared Principles in NF-κB Signaling
Hayden, M. S., & Ghosh, S. (2008) · Cell · doi:10.1016/j.cell.2008.01.020 · Cited by 4,814 · see citing works
Regulation and Function of NF-κB Transcription Factors in the Immune System
Vallabhapurapu, S., & Karin, M. (2009) · Annual Review of Immunology · doi:10.1146/annurev.immunol.021908.132641 · Cited by 2,578 · see citing works
Activation by IKKα of a Second, Evolutionary Conserved, NF-κB Signaling Pathway
Senftleben, U., Cao, Y., Xiao, G., Greten, F. R., Krähn, G. M., Bonizzi, G., Chen, Y., Hu, Y., Fong, A., Sun, S., et al. (2001) · Science · doi:10.1126/science.1062677 · Cited by 1,361 · see citing works
Self-citationMAP3K-related kinase involved in NF-KB induction by TNF, CD95 and IL-1
Malinin, N. L., Boldin, M., Kovalenko, A. V., & Wallach, D. (1997) · Nature · doi:10.1038/385540a0 · Cited by 1,279 · see citing works
IAP Antagonists Induce Autoubiquitination of c-IAPs, NF-κB Activation, and TNFα-Dependent Apoptosis
Varfolomeev, E., Blankenship, J. W., Wayson, S. M., Fedorova, A. V., Kayagaki, N., Garg, P., Zobel, K., Dynek, J. N., Elliott, L. O., Wallweber, H. J. A., et al. (2007) · Cell · doi:10.1016/j.cell.2007.10.030 · Cited by 1,218 · see citing works
IAP Antagonists Target cIAP1 to Induce TNFα-Dependent Apoptosis
Vince, J. E., Wong, W. W.-L., Khan, N. R., Feltham, R., Chau, D., Ahmed, A. U., Benetatos, C. A., Chunduru, S. K., Condon, S. M., McKinlay, M. A., et al. (2007) · Cell · doi:10.1016/j.cell.2007.10.037 · Cited by 1,061 · see citing works
Promiscuous Mutations Activate the Noncanonical NF-κB Pathway in Multiple Myeloma
Keats, J. J., Fonseca, R., Chesi, M., Schop, R., Baker, A., Chng, W.-J., Van Wier, S., Tiedemann, R., Shi, C.-X., Sebag, M., et al. (2007) · Cancer Cell · doi:10.1016/j.ccr.2007.07.003 · Cited by 983 · see citing works
Annunziata, C. M., Davis, R. E., Demchenko, Y., Bellamy, W., Gabrea, A., Zhan, F., Lenz, G., Hanamura, I., Wright, G., Xiao, W., et al. (2007) · Cancer Cell · doi:10.1016/j.ccr.2007.07.004 · Cited by 952 · see citing works
NF-κB-Inducing Kinase Regulates the Processing of NF-κB2 p100
Xiao, G., Harhaj, E. W., & Sun, S. (2001) · Molecular Cell · doi:10.1016/s1097-2765(01)00187-3 · Cited by 836 · see citing works
Self-citationNF- B as a Critical Link Between Inflammation and CancerPreprint
Karin, M. (2009) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a000141 · Cited by 817 · see citing works
BAFF-induced NEMO-independent processing of NF-κB2 in maturing B cells
Claudio, E., Brown, K., Park, S., Wang, H., & Siebenlist, U. K. (2002) · Nature Immunology · doi:10.1038/ni842 · Cited by 694 · see citing works
IKKα limits macrophage NF-κB activation and contributes to the resolution of inflammation
Lawrence, T., Bébien, M., Liu, G. Y., Nizet, V., & Karin, M. (2005) · Nature · doi:10.1038/nature03491 · Cited by 625 · see citing works
Functions of NF-κB1 and NF-κB2 in immune cell biology
Beinke, S., & Ley, S. C. (2004) · Biochemical Journal · doi:10.1042/bj20040544 · Cited by 611 · see citing works
Zarnegar, B. J., Wang, Y., Mahoney, D. J., Dempsey, P. W., Cheung, H. H., He, J., Shiba, T. L., Yang, X., Yeh, W., Mak, T. W., et al. (2008) · Nature Immunology · doi:10.1038/ni.1676 · Cited by 607 · see citing works
Vallabhapurapu, S., Matsuzawa, A., Zhang, W., Tseng, P., Keats, J. J., Wang, H., Vignali, D. A. A., Bergsagel, P. L., & Karin, M. (2008) · Nature Immunology · doi:10.1038/ni.1678 · Cited by 605 · see citing works
NF-κB-inducing kinase activates IKK-α by phosphorylation of Ser-176
Lei, L., Cao, Z., & Goeddel, D. V. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.7.3792 · Cited by 536 · see citing works
Regulation of tissue homeostasis by NF-κB signalling: implications for inflammatory diseases
Pasparakis, M. (2009) · Nature reviews. Immunology · doi:10.1038/nri2655 · Cited by 523 · see citing works
Liao, G., Zhang, M., Harhaj, E. W., & Sun, S. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m403286200 · Cited by 467 · see citing works
Self-citationDejardin, E. (2006) · Biochemical Pharmacology · doi:10.1016/j.bcp.2006.08.007 · Cited by 348 · see citing works
New insights into NF-κB regulation and function
Sun, S., & Ley, S. C. (2008) · Trends in Immunology · doi:10.1016/j.it.2008.07.003 · Cited by 320 · see citing works
Self-citationXiao, G., Fong, A., & Sun, S. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m401428200 · Cited by 296 · see citing works
Self-citationGardam, S., Sierro, F., Basten, A., Mackay, F., & Brink, R. A. (2008) · Immunity · doi:10.1016/j.immuni.2008.01.009 · Cited by 248 · see citing works
Brown, K. D., Claudio, E., & Siebenlist, U. K. (2008) · Arthritis Research & Therapy · doi:10.1186/ar2457 · Cited by 244 · see citing works
Xie, P., Stunz, L. L., Larison, K. D., Yang, B., & Bishop, G. A. (2007) · Immunity · doi:10.1016/j.immuni.2007.07.012 · Cited by 217 · see citing works
Matsushima, A., Kaisho, T., Rennert, P. D., Nakano, H., Kurosawa, K., Uchida, D., Takeda, K., Akira, S., & Matsumoto, M. (2001) · The Journal of Experimental Medicine · doi:10.1084/jem.193.5.631 · Cited by 200 · see citing works
Control of canonical NF-κB activation through the NIK–IKK complex pathway
Zarnegar, B. J., Yamazaki, S., He, J. Q., & Cheng, G. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0707959105 · Cited by 183 · see citing works
Rescue of TRAF3-null mice by p100 NF-κB deficiency
He, J. Q., Zarnegar, B. J., Oganesyan, G., Saha, S. K., Yamazaki, S., Doyle, S. E., Dempsey, P. W., & Cheng, G. (2006) · The Journal of Experimental Medicine · doi:10.1084/jem.20061166 · Cited by 166 · see citing works
Molecular Determinants of NF-κB-Inducing Kinase Action
Lin, X., Mu, Y., Cunningham, E. T., Marcu, K. B., Geleziunas, R., & Greene, W. C. (1998) · Molecular and Cellular Biology · doi:10.1128/mcb.18.10.5899 · Cited by 145 · see citing works
Enhanced NF-κB activation and cellular function in macrophages lacking IκB kinase 1 (IKK1)
Li, Q., Lu, Q., Bottero, V., Estepa, G., Morrison, L., Mercurio, F., & Verma, I. M. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0505997102 · Cited by 123 · see citing works
Razani, B., Zarnegar, B. J., Ytterberg, A. J., Shiba, T. L., Dempsey, P. W., Ware, C. F., Loo, J. A., & Cheng, G. (2010) · Science Signaling · doi:10.1126/scisignal.2000778 · Cited by 120 · see citing works
β-TrCP binding and processing of NF-κB2/p100 involve its phosphorylation at serines 866 and 870
Liang, C., Zhang, M., & Sun, S. (2005) · Cellular Signalling · doi:10.1016/j.cellsig.2005.10.011 · Cited by 112 · see citing works
Self-citation
Flagged first, then by citations
Cited by
Sorted by citations
Targeting NF-κB pathway for the therapy of diseases: mechanism and clinical study
Yu, H., Lin, L., Zhang, Z., Zhang, H., & Hu, H. (2020) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-020-00312-6 · Cited by 2,236 · see citing works
Chromosomal instability drives metastasis through a cytosolic DNA response
Bakhoum, S. F., Ngo, B., Laughney, A. M., Cavallo, J.-A., Murphy, C. J., Ly, P., Shah, P., Sriram, R. K., Watkins, T. B. K., Taunk, N. K., et al. (2018) · Nature · doi:10.1038/nature25432 · Cited by 1,638 · see citing works
Non-canonical NF-κB signaling pathway
Sun, S. (2010) · Cell Research · doi:10.1038/cr.2010.177 · Cited by 1,200 · see citing works
Self-citationThe noncanonical NF‐κB pathway
Sun, S. (2012) · Immunological Reviews · doi:10.1111/j.1600-065x.2011.01088.x · Cited by 724 · see citing works
Self-citationNF‐κB signaling in inflammation and cancer
Zhang, T., Ma, C., Zhang, Z., Zhang, H., & Hu, H. (2021) · MedComm · doi:10.1002/mco2.104 · Cited by 615 · see citing works
Expanding role of ubiquitination in NF-κB signaling
Liu, S., & Chen, Z. J. (2010) · Cell Research · doi:10.1038/cr.2010.170 · Cited by 243 · see citing works
Yamamoto, M., Taguchi, Y., Ito-Kureha, T., Semba, K., Yamaguchi, N., & Inoue, J. (2013) · Nature Communications · doi:10.1038/ncomms3299 · Cited by 186 · see citing works
McDaniel, D. K., Eden, K. B., Ringel-Scaia, V. M., & Allen, I. C. (2016) · Inflammatory Bowel Diseases · doi:10.1097/mib.0000000000000858 · Cited by 166 · see citing works
NIK/MAP3K14 Regulates Mitochondrial Dynamics and Trafficking to Promote Cell Invasion
Jung, J.-U., Ravi, S., Lee, D. W., McFadden, K., Kamradt, M. L., Toussaint, L. G., & Sitcheran, R. (2016) · Current Biology · doi:10.1016/j.cub.2016.10.009 · Cited by 106 · see citing works
Cherry, E. M., Lee, D. W., Jung, J.-U., & Sitcheran, R. (2015) · Molecular Cancer · doi:10.1186/s12943-014-0273-1 · Cited by 78 · see citing works
NF-kappaΒ-inducing kinase regulates stem cell phenotype in breast cancer
Vázquez-Santillán, K., Meléndez-Zajgla, J., Jimenez-Hernandez, L. E., Gaytán-Cervantes, J., Muñoz-Galindo, L., Piña‐Sánchez, P., Martinez‐Ruíz, G. U., Torres, J., García‐López, P., González-Torres, C., et al. (2016) · Scientific Reports · doi:10.1038/srep37340 · Cited by 71 · see citing works
The Ubiquitin System in Immune Regulation
Park, Y., Jin, H., Aki, D., Lee, J., & Liu, Y. (2014) · Advances in immunology · doi:10.1016/b978-0-12-800147-9.00002-9 · Cited by 67 · see citing works
Noncanonical NF-κB Signaling Is Limited by Classical NF-κB Activity
Gray, C. M., Remouchamps, C., McCorkell, K. A., Solt, L. A., Dejardin, E., Orange, J. S., & May, M. J. (2014) · Science Signaling · doi:10.1126/scisignal.2004557 · Cited by 62 · see citing works
The Fire Within: NF-κB Involvement in Non–Small Cell Lung Cancer
Dimitrakopoulos, F.-I. D., Kottorou, A. E., Kalofonou, M., & Kalofonos, H. P. (2020) · Cancer Research · doi:10.1158/0008-5472.can-19-3578 · Cited by 61 · see citing works
Shibata, Y., Oyama, M., Kozuka‐Hata, H., Han, X., Tanaka, Y., Gohda, J., & Inoue, J. (2012) · Nature Communications · doi:10.1038/ncomms2068 · Cited by 60 · see citing works
Liu, J., Sudom, A. M., Min, X., Cao, Z., Gao, X., Ayres, M., Lee, F., Cao, P., Johnstone, S., Plotnikova, O. V., et al. (2012) · Journal of Biological Chemistry · doi:10.1074/jbc.m112.366658 · Cited by 60 · see citing works
Chung, S., Sundar, I. K., Hwang, J., Yull, F. E., Blackwell, T. S., Kinnula, V. L., Bulger, M., Yao, H., & Rahman, I. (2011) · PLoS ONE · doi:10.1371/journal.pone.0023488 · Cited by 53 · see citing works
Host microRNAs and exosomes that modulate influenza virus infection
Zheng, B., Zhou, J., & Wang, H. (2020) · Virus Research · doi:10.1016/j.virusres.2020.197885 · Cited by 52 · see citing works
The Role of NF-κB in Myocardial Ischemia/Reperfusion Injury
Han, H., Dong, P., & Liu, K. (2022) · Current Protein and Peptide Science · doi:10.2174/1389203723666220817085941 · Cited by 51 · see citing works
The NF-κB Pathway: a Focus on Inflammatory Responses in Spinal Cord Injury
Ding, Y., & Chen, Q. (2023) · Molecular Neurobiology · doi:10.1007/s12035-023-03411-x · Cited by 53 · see citing works
Nano NiO induced liver toxicity via activating the NF-κB signaling pathway in rats
Liu, F., Chang, X., Tian, M., Zhu, A., Zou, L., Han, A., Su, L., Li, S., & Sun, Y. (2017) · Toxicology Research · doi:10.1039/c6tx00444j · Cited by 49 · see citing works
Mir‐302c mediates influenza A virus‐induced IFNβ expression by targeting NF‐κB inducing kinase
Gui, S., Chen, X., Zhang, M., Zhao, F., Wan, Y., Wang, L., Xu, G., Zhou, L., Yue, X., Zhu, Y., et al. (2015) · FEBS Letters · doi:10.1016/j.febslet.2015.11.011 · Cited by 48 · see citing works
NF‐κB‐inducing kinase is essential for B‐cell maintenance in mice
Hahn, M., Macht, A., Waisman, A., & Hövelmeyer, N. (2015) · European Journal of Immunology · doi:10.1002/eji.201546081 · Cited by 43 · see citing works
The NF-κB signaling network in the life of T cells
Daniels, M., & Teixeiro, E. (2025) · Frontiers in Immunology · doi:10.3389/fimmu.2025.1559494 · Cited by 44 · see citing works
NIK as a Druggable Mediator of Tissue Injury
Rivas, L. V., Vaquero, J. J., Sucunza, D., Gutiérrez, S., Sanz, A. B., Fresno, M., Ortíz, A., & Sánchez-Niño, M. D. (2019) · Trends in Molecular Medicine · doi:10.1016/j.molmed.2019.02.005 · Cited by 42 · see citing works
Shi, W., Ye, Z., Li, Z., Li, Y., Shuai, W., Zuo, Z., Mao, X., Liu, R., Wu, J., Chen, S., et al. (2016) · The Journal of Pathology · doi:10.1002/path.4784 · Cited by 41 · see citing works
Tropomodulin 1 Expression Driven by NF-κB Enhances Breast Cancer Growth
Ito-Kureha, T., Koshikawa, N., Yamamoto, M., Semba, K., Yamaguchi, N., Yamamoto, T. S., Seiki, M., & Inoue, J. (2014) · Cancer Research · doi:10.1158/0008-5472.can-13-3455 · Cited by 38 · see citing works
NF-κB Inducing Kinase Regulates Intestinal Immunity and Homeostasis
Wang, B., & Shen, J. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.895636 · Cited by 38 · see citing works
Research progress on rodent models and its mechanisms of liver injury
Mao, J., Tan, L., Cheng, T., Wang, W., Zhang, H., Zhu, Z., & Li, Y. (2023) · Life Sciences · doi:10.1016/j.lfs.2023.122343 · Cited by 38 · see citing works
TRAF3 signaling: Competitive binding and evolvability of adaptive viral molecular mimicry
Guven‐Maiorov, E., Keskin, Ö., Gürsoy, A., Waes, C. V., Chen, Z., Tsai, C., & Nussinov, R. (2016) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/j.bbagen.2016.05.021 · Cited by 34 · see citing works
The Roles of RhoA/ROCK/NF-κB Pathway in Microglia Polarization Following Ischemic Stroke
Lu, W., Wang, Y., & Wen, J. (2024) · Journal of Neuroimmune Pharmacology · doi:10.1007/s11481-024-10118-w · Cited by 32 · see citing works
Duran, C. L., Lee, D. W., Jung, J.-U., Ravi, S., Pogue, C. B., Toussaint, L. G., Bayless, K. J., & Sitcheran, R. (2016) · Oncogenesis · doi:10.1038/oncsis.2016.39 · Cited by 32 · see citing works
NF-kB and the CLL microenvironment
O'Donnell, A., Pepper, C., Mitchell, S. M. S., & Pepper, A. (2023) · Frontiers in Oncology · doi:10.3389/fonc.2023.1169397 · Cited by 32 · see citing works
Inflammation and cancer cell survival: TRAF2 as a key player
Albini, A., Paola, L. D., Mei, G., Baci, D., Fusco, N., Corso, G., & Noonan, D. M. (2025) · Cell Death and Disease · doi:10.1038/s41419-025-07609-w · Cited by 31 · see citing works
Trares, K., Ackermann, J., & Koch, I. (2021) · Biosystems · doi:10.1016/j.biosystems.2021.104564 · Cited by 28 · see citing works
Cheng, J., Feng, X., Li, Z., Zhou, F., Yang, J., & Zhao, Y. (2021) · RSC Medicinal Chemistry · doi:10.1039/d0md00361a · Cited by 27 · see citing works
CD147 regulates extrinsic apoptosis in spermatocytes by modulating NFκB signaling pathways
Wang, C., Fok, K. L., Cai, Z., Chen, H., & Chan, H. C. (2016) · Oncotarget · doi:10.18632/oncotarget.13624 · Cited by 27 · see citing works
The role of NF-κB-SOX9 signalling pathway in osteoarthritis
Tian, B., Zhang, L., Zheng, J., & Kang, X. (2024) · Heliyon · doi:10.1016/j.heliyon.2024.e37191 · Cited by 22 · see citing works
B-Cell Activating Factor as a Cancer Biomarker and Its Implications in Cancer-Related Cachexia
Říháček, M., Vašků, J. B., Valík, D., Štěrba, J., Pilátová, K., & Dubská, L. Z. (2015) · BioMed Research International · doi:10.1155/2015/792187 · Cited by 23 · see citing works
de Jong, S. J., Albrecht, J., Giehler, F., Kieser, A., Sticht, H., & Biesinger, B. (2013) · Science Signaling · doi:10.1126/scisignal.2003309 · Cited by 19 · see citing works
Kim, N.-S., Mbongue, J. C., Nicholas, D., Esebanmen, G. E., Unternaehrer, J., Firek, A. F., & Langridge, W. H. R. (2016) · PLoS ONE · doi:10.1371/journal.pone.0147509 · Cited by 17 · see citing works
Espinoza‐Sánchez, N. A., Győrffy, B., Fuentes‐Pananá, E. M., & Götte, M. (2019) · Journal of Cancer · doi:10.7150/jca.34302 · Cited by 18 · see citing works
Post-translational modification of MALT1 and its role in B cell- and T cell-related diseases
Zhang, Y., Peng, J., & Luo, X. (2022) · Biochemical Pharmacology · doi:10.1016/j.bcp.2022.114977 · Cited by 16 · see citing works
Lin, L., Yu, H., Li, L., Yang, W., Chen, X., Gong, Y., Lei, Q., Li, Z., Zhou, Z., Dai, L., et al. (2023) · Science Signaling · doi:10.1126/scisignal.abn5410 · Cited by 16 · see citing works
Thakar, N. Y., Ovchinnikov, D. A., Hastie, M. L., Gorman, J. J., & Wolvetang, E. J. (2015) · Stem Cells and Development · doi:10.1089/scd.2014.0587 · Cited by 13 · see citing works
Gray, C. M., McCorkell, K. A., Chunduru, S. K., McKinlay, M. A., & May, M. J. (2014) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2014.05.122 · Cited by 13 · see citing works
The path less traveled: the non-canonical NF-κB pathway in systemic lupus erythematosus
Montano, H., Allen, I. C., & Reilly, C. M. (2025) · Frontiers in Immunology · doi:10.3389/fimmu.2025.1588486 · Cited by 12 · see citing works
Noncanonical NF-κB Signaling Pathway in Liver Diseases
Chen, Q., Lu, X., & Zhang, X. (2020) · Journal of Clinical and Translational Hepatology · doi:10.14218/jcth.2020.00063 · Cited by 30 · see citing works
Expression of intestinal CD40 after experimental traumatic brain injury in rats
Hu, Y.-C., Wang, F., Zhang, D.-D., Sun, Q., Li, W., Dai, Y., Zhou, M., & Hang, C. (2013) · Journal of Surgical Research · doi:10.1016/j.jss.2013.04.005 · Cited by 11 · see citing works
Zhou, Y., Kang, X., Xiong, D., Zhu, S., Zheng, H., Xu, Y., Guo, Y., Pan, Z., & Jiao, X. (2016) · Developmental & Comparative Immunology · doi:10.1016/j.dci.2016.12.005 · Cited by 9 · see citing works
p52 signaling promotes cellular senescence
Bernal, G. M., Wu, L., Voce, D. J., Weichselbaum, R. R., & Yamini, B. (2022) · Cell & Bioscience · doi:10.1186/s13578-022-00779-6 · Cited by 8 · see citing works
Guan, F., Wang, L., Hao, S., Wu, Z., Bai, J., Kang, Z., Zhou, Q., Chang, H., Yin, H., Li, D., et al. (2017) · Oncotarget · doi:10.18632/oncotarget.22166 · Cited by 8 · see citing works
Long, D., Mao, C., Zhu, Y., & Xu, Y. (2025) · Frontiers in Nutrition · doi:10.3389/fnut.2025.1594120 · Cited by 7 · see citing works
Quantitative assessment of NFκB transcription factor activity
Hunter, T., Fear, D. J., Lavender, P., Spencer, J., Peakman, M., & Ibrahim, M. A. A. (2020) · Journal of Immunological Methods · doi:10.1016/j.jim.2020.112954 · Cited by 1 · see citing works
The Role of Traditional Chinese Medicine in Targeting NF-κB Ubiquitination Against Ischemic Stroke
Ding, J., Qiu, Y., Fang, Y., & Peng, X. (2025) · The American Journal of Chinese Medicine · doi:10.1142/s0192415x25500521 · Cited by 1 · see citing works
The NF-κB-inducing kinase: a central regulator of immunity and autoimmune diseases
Yu, L., 毛宏梅, & Sun, S. (2026) · Immunity & Inflammation · doi:10.1007/s44466-026-00026-4 · Cited by 1 · see citing works
Self-citationNF-κB Signaling in Osteoclastogenesis
Taguchi, Y., Gohda, J., & Inoue, J. (2015) · Springer eBooks · doi:10.1007/978-4-431-55561-2_13 · Cited by 1 · see citing works
Reid, A. M. (2011) · Enlighten: Theses (The University of Glasgow)
Role of the COP9 signalosome and IKK complexes in atherosclerosis
Asare, Y., & Bernhagen, J. (2013) · RWTH Publications (RWTH Aachen)
Characterization of Biomedical and Incidental Nanoparticles in the Lungs and Their Effects on Health
McDaniel, D. K. (2018) · VTechWorks (Virginia Tech)
Wächtershäuser, K. N., Schneider, J. V., Geßner, A., Andrieux, G., Kur, I.-M., Duschek, N., Weigert, A., Boerries, M., Rieger, M. A., Stelzer, E. H. K., et al. (2026) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-026-02755-9 · Cited by 1 · see citing works
- Authors
- Sun, S.-C.
- Affiliations
- The University of Texas MD Anderson Cancer Center (US)
- Corresponding author
- Sun, Shao-Cong
- ORCID
- Sun, Shao-Cong
- Venue
- Science Signaling
- Published
- 2010-05-25
- Volume
- 3
- Issue
- 123
- Pages
- pe18-pe18
- ISSN
- 1937-9145 (ISSN-L)
- 1945-0877
- PMC
- PMC5753754
- OpenAlex
- W2088638587
- Cited by
- 61
- References
- 31
- Citations by year
- 2026: 2 · 2025: 5 · 2024: 2 · 2023: 4 · 2022: 4 · 2021: 3 · 2020: 5 · 2019: 2 · 2018: 2 · 2017: 2 · 2016: 9 · 2015: 6 · 2014: 4 · 2013: 4 · 2012: 3
- FWCI
- 1.11
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Science Signaling (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institute of General Medical Sciences (R01GM084459, GM084459)
- National Institute of Allergy and Infectious Diseases (AI064639, R01AI057555, R37AI064639, R01AI064639, AI057555)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cancer Research › NF-κB Signaling Pathways
- Life Sciences › Immunology and Microbiology › Immunology › Immune Response and Inflammation
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Signaling Pathways in Disease
- Keywords
- NF-κB signaling, non-canonical NF-κB signaling, NIK, IKKα, phosphorylation, feedback regulation, protein stability, immune function
- MeSH terms
- NF-kappaB-Inducing Kinase, Animals, Humans, Models, Biological, Signal Transduction, NF-kappa B, Protein Serine-Threonine Kinases, Feedback, Physiological, I-kappa B Kinase
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review