The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.
Massive ex Vivo Expansion of Human Natural Regulatory T Cells (T regs ) with Minimal Loss of in Vivo Functional Activity
Open accessAbstract
A good manufacturing grade–compatible approach generates massive numbers of natural regulatory T cells that retain suppressive function in vivo.
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Citations
Cites
CD127 expression inversely correlates with FoxP3 and suppressive function of human CD4+ T reg cells
Liu, W., Putnam, A. L., Xu-yu, Z., Szot, G. L., Lee, M. R., Zhu, S., Gottlieb, P. A., Kapranov, P., Gingeras, T. R., de St. Groth, B. F., et al. (2006) · The Journal of Experimental Medicine · doi:10.1084/jem.20060772 · Cited by 2,606
Brenchley, J. M., Karandikar, N. J., Betts, M. R., Ambrozak, D. R., Hill, B. J., Crotty, L. E., Casazza, J. P., Kuruppu, J., Migueles, S. A., Connors, M., et al. (2003) · Blood · doi:10.1182/blood-2002-07-2103 · Cited by 1,073
Self-citationCD8 + T‐cell memory in tumor immunology and immunotherapy
Klebanoff, C. A., Gattinoni, L., & Restifo, N. P. (2006) · Immunological Reviews · doi:10.1111/j.0105-2896.2006.00391.x · Cited by 511 · cited 1×
“Restimulated nTregs differentiated from a CD27 memory phenotype to CD27 memory phenotype but, importantly, did not adopt a senescent (CD57) phenotype (33, 34).”
BackgroundCoenen, J. J. A., Koenen, H. J. P. M., van Rijssen, E., Hilbrands, L. B., & Joosten, I. (2006) · Blood · doi:10.1182/blood-2005-07-3032 · Cited by 252
Cited by
Regulatory T Cells and Human Disease
Sakaguchi, S., Mikami, N., Wing, J. B., Tanaka, A., Ichiyama, K., & Ohkura, N. (2020) · Annual Review of Immunology · doi:10.1146/annurev-immunol-042718-041717 · Cited by 1,120
Type 1 diabetes immunotherapy using polyclonal regulatory T cells
Bluestone, J. A., Buckner, J. H., Fitch, M., Gitelman, S. E., Gupta, S., Hellerstein, M. K., Herold, K. C., Lares, A., Lee, M. R., Li, K., et al. (2015) · Science Translational Medicine · doi:10.1126/scitranslmed.aad4134 · Cited by 1,033
Human FOXP3+ Regulatory T Cell Heterogeneity and Function in Autoimmunity and Cancer
Wing, J. B., Tanaka, A., & Sakaguchi, S. (2019) · Immunity · doi:10.1016/j.immuni.2019.01.020 · Cited by 726
Induced CD4+Foxp3+Regulatory T Cells in Immune Tolerance
Bilate, A. M., & Lafaille, J. J. (2012) · Annual Review of Immunology · doi:10.1146/annurev-immunol-020711-075043 · Cited by 569
Alloantigen-specific regulatory T cells generated with a chimeric antigen receptor
MacDonald, K. G., Hoeppli, R. E., Huang, Q., Gillies, J., Luciani, D. S., Orban, P. C., Broady, R., & Levings, M. K. (2016) · Journal of Clinical Investigation · doi:10.1172/jci82771 · Cited by 494
Metadata
- Authors
- Hippen, K. L., Merkel, S. C., Schirm, D. K., Sieben, C. M., Sumstad, D., Kadidlo, D. M., McKenna, D. H., Bromberg, J. S., Levine, B. L., Riley, J. L., June, C. H., Scheinberg, P., Douek, D. C., Miller, J. S., Wagner, J. E., & Blazar, B. R.
- Venue
- Science Translational Medicine
- Published
- 2011-05-18
- Volume
- 3
- Issue
- 83
- Pages
- 83ra41-83ra41
- ISSN
- 1946-6234 (ISSN-L)
- 1946-6242
- OpenAlex
- W2145353379
- Cited by
- 365
- References
- 4
- FWCI
- 13.87
- Type
- journal article
- Language
- en
- Open access
- green
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- CoChat. (2026). Citation check: Massive ex Vivo Expansion of Human Natural Regulatory T Cells (T regs ) with Minimal Loss of in Vivo Functional Activity. https://app.cochat.ai/papers/10.1126/scitranslmed.3001809
- The paper
- Hippen, K. L., Merkel, S. C., Schirm, D. K., Sieben, C. M., Sumstad, D., Kadidlo, D. M., McKenna, D. H., Bromberg, J. S., Levine, B. L., Riley, J. L., June, C. H., Scheinberg, P., Douek, D. C., Miller, J. S., Wagner, J. E., & Blazar, B. R. (2011). Massive ex Vivo Expansion of Human Natural Regulatory T Cells (T regs ) with Minimal Loss of in Vivo Functional Activity. Science Translational Medicine. https://doi.org/10.1126/scitranslmed.3001809
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
