Cited by 327Cancer Genomics and DiagnosticsCervical Cancer and HPV ResearchOvarian cancer diagnosis and treatment

Evaluation of DNA from the Papanicolaou test to detect ovarian and endometrial cancers.

Open access
Kinde, Isaac, Bettegowda, Chetan, Wang, Yuxuan, Wu, Jian, Agrawal, Nishant, Shih, Ie-Ming, Kurman, Robert, Dao, Fanny +10 more·2013·Science Translational Medicine

Abstract

Mutant DNA from ovarian and endometrial tumors can be detected in Pap smear specimens through massively parallel sequencing.

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Crossref · 10.1126/scitranslmed.3004952

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  1. [13]ACOG Committee on Practice Bulletins, ACOG Practice Bulletin Clinical Management Guidelines for Obstetrician-Gynecologists. Number 60, March 2005. Pregestational diabetes mellitus Obstet Gynecol 105 675 685 2005 15738045

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Authors
Kinde, I., Bettegowda, C., Wang, Y., Wu, J., Agrawal, N., Shih, I.-M., Kurman, R., Dao, F., Levine, D. A., Giuntoli, R., Roden, R., Eshleman, J. R., Carvalho, J. P., Marie, S. K. N., Papadopoulos, N., Kinzler, K. W., Vogelstein, B., & Diaz, L. A.
Affiliations
  • Howard Hughes Medical Institute (US)
  • Johns Hopkins University (US)
  • Memorial Sloan Kettering Cancer Center (US)
  • Universidade de São Paulo (BR)
Corresponding author
  • Kinde, Isaac
  • Bettegowda, Chetan
  • Wang, Yuxuan
  • Vogelstein, Bert
  • Diaz, Luis A.
Venue
Science Translational Medicine
Published
2013-01-09
Volume
5
Issue
167
Pages
167ra4-167ra4
ISSN
  • 1946-6234 (ISSN-L)
  • 1946-6242
OpenAlex
W2160541773
Cited by
327
References
52
Citations by year
2026: 12 · 2025: 20 · 2024: 10 · 2023: 21 · 2022: 20 · 2021: 24 · 2020: 22 · 2019: 36 · 2018: 23 · 2017: 31 · 2016: 19 · 2015: 37 · 2014: 23 · 2013: 25
FWCI
12.20
Type
journal article
Language
en
Open access
Locations
  • Science Translational Medicine (publishedVersion)
  • PubMed (publishedVersion)
  • Europe PMC (PubMed Central) (acceptedVersion)
  • PubMed Central (acceptedVersion)
Funders
  • Howard Hughes Medical Institute
  • National Institutes of Health (n01cn43309-10-0-1)
  • National Cancer Institute (N01 CN043309, R01CA129825, CA43460, N01 CN43309, R37CA043460, CA129825, P50CA062924, CA062924, P50CA098252)
Topics
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Cancer Research › Cancer Genomics and Diagnostics
  • Health Sciences › Medicine › Epidemiology › Cervical Cancer and HPV Research
  • Health Sciences › Medicine › Reproductive Medicine › Ovarian cancer diagnosis and treatment
Keywords
endometrial cancer, ovarian cancer, tumor DNA detection, somatic mutations, liquid biopsy, gynecologic cancer screening, early cancer detection, exome sequencing, next-generation sequencing
MeSH terms
DNA, Neoplasm, Female, Humans, Mutation, Ovarian Neoplasms, Vaginal Smears, Endometrial Neoplasms, Papanicolaou Test

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