The DOI matches its Crossref record; 315 of the 315 references it cites were found in a registry or an index.
Cell and tissue engineering for liver disease
Open accessAbstract
Advances in cell and tissue engineering are moving cell-based therapies for treating liver disease and liver failure closer to the clinic.
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“These iPSC-derived hepatocyte-like cells are still in nascent stages of development and show characteristics similar to fetal hepatocytes [76].”
From A liver-on-a-chip platform with bioprinted hepatic spheroids (2016) · cites this paper as [76]
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“For decades, expandable HHs have been a bottleneck for their applications for research purposes and clinical therapies (Bhatia et al., 2014; Michalopoulos, 2014; Mitaka, 1998; Runge et al., 2000”
From In Vitro Expansion of Primary Human Hepatocytes with Efficient Liver Repopulation Capacity (2018) · cites this paper as Bhatia et al., 2014
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“However, the actual use of hepatocyte transplantation has been hampered by the limited availability of donor hepatocytes and the inability to expand primary HHs (PHHs) in vitro.”
From In Vitro Expansion of Primary Human Hepatocytes with Efficient Liver Repopulation Capacity (2018) · cites this paper as Bhatia et al., 2014
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Cites
Lozano, R., Naghavi, M., Foreman, K., Lim, S., Shibuya, K., Aboyans, V., Abraham, J., Adair, T., Aggarwal, R., Ahn, S. Y., et al. (2012) · The Lancet · doi:10.1016/s0140-6736(12)61728-0 · Cited by 14,070
The HCV Life Cycle: In vitro Tissue Culture Systems and Therapeutic Targets
Gerold, G., & Pietschmann, T. (2014) · Digestive Diseases · doi:10.1159/000360830 · Cited by 4,871
Hydrogels for biomedical applications
Hoffman, A. S. (2002) · Advanced Drug Delivery Reviews · doi:10.1016/s0169-409x(01)00239-3 · Cited by 4,864
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Berry, M. N., & Friend, D. S. (1969) · The Journal of Cell Biology · doi:10.1083/jcb.43.3.506 · Cited by 4,407
Organoid Models and Applications in Biomedical Research
Xinaris, C., Brizi, V., & Remuzzi, G. (2015) · The Nephron journals/Nephron journals · doi:10.1159/000433566 · Cited by 3,519
Michalopoulos, G. K., & DeFrances, M. C. (1997) · Science · doi:10.1126/science.276.5309.60 · Cited by 2,828
Replication of Subgenomic Hepatitis C Virus RNAs in a Hepatoma Cell Line
Lohmann, V., Körner, F., Koch, J. O., Herian, U., Lorenz Theilmann, I., & Bartenschlager, R. F. W. (1999) · Science · doi:10.1126/science.285.5424.110 · Cited by 2,813
Production of infectious hepatitis C virus in tissue culture from a cloned viral genome
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Boceprevir for Untreated Chronic HCV Genotype 1 Infection
Poordad, F. F., McCone, J., Bacon, B. R., Bruno, S., Manns, M. P., Sulkowski, M., Jacobson, I. M., Reddy, K. R., Goodman, Z. D., Boparai, N., et al. (2011) · New England Journal of Medicine · doi:10.1056/nejmoa1010494 · Cited by 2,512
Primary liver cancer: Worldwide incidence and trends
Bosch, F. X., Ribes, J., Díaz, M., & Clèries, R. (2004) · Gastroenterology · doi:10.1053/j.gastro.2004.09.011 · Cited by 2,473
Research works printed but not linked: 4
- 10.1126/science.276.5309.60 · DOI · Paper page
- Ding J., Roy-Chowdhury N., Wang X., Neufeld D. S., Hansel M. C., Strom S. C., Fox I. J., Guha C., Roy-Chowdhury J., SCID/Piz mice: A novel animal model for evaluating engraftment and proliferation of human stem cell-derived hepatocytes. Hepatology 54, 957A (2011).
- Roy-Chowdhury N., Chen Y., Atienza K., Chang C., Wang X., Guha C., Fox I. J., Bouhassira E. E., Roy-Chowdhury J., Amelioration of hyperbilirubinemia in Gunn rats after transplantation of human hepatocytes derived from induced pluripotent stem cells. Hepatology 52, 426A (2010).
- Atienza K. V., Ding J., Chang C. J., Bouhassira E. E., Chen Y., Wang X., Avsar Y., Laibin L., Guha C., Fox I. J., Salido E., Roy-Chowdhury J., Roy-Chowdhury N., Reduction of urinary oxalate excretion after transplantation of human induced pluripotent stem cell-derived hepatocytes in a mouse model of primary hyperoxaluria-1. Hepatology 54, 412A (2011).
Cited by
Sorted by citations
A liver-on-a-chip platform with bioprinted hepatic spheroids
Bhise, N. S., Manoharan, V., Massa, S., Tamayol, A., Ghaderi, M., Miscuglio, M., Lang, Q., Shrike Zhang, Y., Shin, S. R., Calzone, G., et al. (2016) · Biofabrication · doi:10.1088/1758-5090/8/1/014101 · Cited by 615
Hepatic fibrosis 2022: Unmet needs and a blueprint for the future
Friedman, S. L., & Pinzani, M. (2022) · Hepatology · doi:10.1002/hep.32285 · Cited by 430
Orchestrating liver development
Gordillo, M., Evans, T., & Gouon-Evans, V. (2015) · Development · doi:10.1242/dev.114215 · Cited by 375
In Vitro Expansion of Primary Human Hepatocytes with Efficient Liver Repopulation Capacity
Zhang, K., Zhang, L., Liu, W., Ma, X., Cen, J., Sun, Z., Wang, C., Feng, S., Zhang, Z., Yue, L., et al. (2018) · Cell Stem Cell · doi:10.1016/j.stem.2018.10.018 · Cited by 252
Yoon No, D., Lee, K.-H., Lee, J., & Lee, S.-H. (2015) · Lab on a Chip · doi:10.1039/c5lc00611b · Cited by 205
Metadata
- Authors
- Bhatia, S. N., Underhill, G. H., Zaret, K. S., & Fox, I. J.
- Affiliations
- Brigham and Women's Hospital (US)
- University of Illinois Urbana-Champaign (US)
- University of Pennsylvania (US)
- University of Pittsburgh (US)
- Corresponding author
- Bhatia, Sangeeta N.
- Venue
- Science Translational Medicine
- Published
- 2014-07-16
- Volume
- 6
- Issue
- 245
- Pages
- 245sr2-245sr2
- ISSN
- 1946-6234 (ISSN-L)
- 1946-6242
- PMC
- PMC4374645
- OpenAlex
- W2109789900
- Cited by
- 309
- References
- 315
- Citations by year
- 2026: 11 · 2025: 15 · 2024: 20 · 2023: 15 · 2022: 24 · 2021: 41 · 2020: 40 · 2019: 32 · 2018: 26 · 2017: 31 · 2016: 34 · 2015: 15 · 2014: 3
- FWCI
- 5.22
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Science Translational Medicine (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- Howard Hughes Medical Institute
- National Institute of General Medical Sciences (R01GM036477, R37GM36477, R37GM036477)
- National Institute of Diabetes and Digestive and Kidney Diseases (R01DK099320, P01DK096990, R01DK48794, R01DK085713, R01DK85713, R01DK048794)
- National Institute of Biomedical Imaging and Bioengineering (R01EB008396, UH2EB017103, UH3EB017103)
- Topics
- Health Sciences › Medicine › Surgery › Tissue Engineering and Regenerative Medicine
- Health Sciences › Medicine › Hepatology › Liver physiology and pathology
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Mesenchymal stem cell research
- Keywords
- liver disease, liver failure, cell therapy, tissue engineering, stem cells, cellular reprogramming, clinical translation, liver regeneration
- MeSH terms
- Animals, Disease Models, Animal, Humans, Liver, Liver Diseases, Tissue Engineering, Translational Research, Biomedical, Cell Engineering
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