Zaret, Kenneth S.

Pioneer transcription factors: establishing competence for gene expression

Zaret, K. S., & Carroll, J. S. (2011) · Genes & Development

Genomics and Chromatin DynamicsChromatin Remodeling and Cancer

Cited by 1,589

Pioneer Transcription Factors Target Partial DNA Motifs on Nucleosomes to Initiate Reprogramming

Soufi, A., Garcia, M. F., Jaroszewicz, A., Osman, N., Pellegrini, M., & Zaret, K. S. (2015) · Cell

Genomics and Chromatin DynamicsPluripotent Stem Cells Research

Cited by 780

Initiation of Mammalian Liver Development from Endoderm by Fibroblast Growth Factors

Jung, J., Zheng, M., Goldfarb, M., & Zaret, K. S. (1999) · Science

Liver physiology and pathologyFibroblast Growth Factor Research

Cited by 721

The formation and maintenance of the definitive endoderm lineage in the mouse: involvement of HNF3/forkhead proteins

Ang, S.-L., Wierda, A., Wong, D., Stevens, K. A., Cascio, S., Rossant, J., & Zaret, K. S. (1993) · Development

Developmental Biology and Gene RegulationPluripotent Stem Cells Research

Cited by 618

A bipotential precursor population for pancreas and liver within the embryonic endoderm

Deutsch, G., Jung, J., Zheng, M., Lóra, J., & Zaret, K. S. (2001) · Development

Developmental Biology and Gene RegulationPancreatic function and diabetes

Cited by 611

Hepatocyte nuclear factor 4α controls the development of a hepatic epithelium and liver morphogenesis

Parviz, F., Matullo, C., Garrison, W. D., Savatski, L., Adamson, J. W., Ning, G., Kaestner, K. H., Rossi, J. M., Zaret, K. S., & Duncan, S. A. (2003) · Nature Genetics

Liver physiology and pathologyDevelopmental Biology and Gene Regulation

Cited by 588

The Pioneer Transcription Factor FoxA Maintains an Accessible Nucleosome Configuration at Enhancers for Tissue-Specific Gene Activation

Iwafuchi-Doi, M., Donahue, G., Kakumanu, A., Watts, J. A., Mahony, S., Pugh, B. F., Lee, D., Kaestner, K. H., & Zaret, K. S. (2016) · Molecular Cell

Genomics and Chromatin DynamicsChromatin Remodeling and Cancer

Cited by 390

GATA transcription factors as potentiators of gut endoderm differentiation

Bossard, P., & Zaret, K. S. (1998) · Development

Developmental Biology and Gene RegulationGenomics and Chromatin Dynamics

Cited by 313

Role of H3K9me3 heterochromatin in cell identity establishment and maintenance

Nicetto, D., & Zaret, K. S. (2019) · Current Opinion in Genetics & Development

Genomics and Chromatin DynamicsEpigenetics and DNA Methylation

Cited by 312

Building consensus on definition and nomenclature of hepatic, pancreatic, and biliary organoids

Marsee, A., Roos, F. J. M., Verstegen, M. M. A., Marsee, A., Roos, F., Verstegen, M., Clevers, H., Vallier, L., Takebe, T., Huch, M., et al. (2021) · Cell Stem Cell

3D Printing in Biomedical ResearchPancreatic function and diabetes

Cited by 310

Cell and tissue engineering for liver disease

Bhatia, S. N., Underhill, G. H., Zaret, K. S., & Fox, I. J. (2014) · Science Translational Medicine

Tissue Engineering and Regenerative MedicineLiver physiology and pathology

Cited by 309

Cell fate control by pioneer transcription factors

Iwafuchi-Doi, M., & Zaret, K. S. (2016) · Development

Genomics and Chromatin DynamicsDevelopmental Biology and Gene Regulation

Cited by 304

Distinct populations of endoderm cells converge to generate the embryonic liver bud and ventral foregut tissues

Tremblay, K. D., & Zaret, K. S. (2005) · Developmental Biology

Developmental Biology and Gene RegulationPluripotent Stem Cells Research

Cited by 299

Detection of early pancreatic ductal adenocarcinoma with thrombospondin-2 and CA19-9 blood markers

Kim, J., Bamlet, W. R., Oberg, A. L., Chaffee, K. G., Donahue, G., Cao, X.-J., Chari, S., Garcia, B. A., Petersen, G. M., & Zaret, K. S. (2017) · Science Translational Medicine

Pancreatic and Hepatic Oncology ResearchPancreatitis Pathology and Treatment

Cited by 269

Hex homeobox gene-dependent tissue positioning is required for organogenesis of the ventral pancreas

Bort, R., Martinez-Barbera, J. P., Beddington, R. S. P., & Zaret, K. S. (2004) · Development

Developmental Biology and Gene RegulationPancreatic function and diabetes

Cited by 267

Nucleosome-binding affinity as a primary determinant of the nuclear mobility of the pioneer transcription factor FoxA

Sekiya, T., Muthurajan, U. M., Luger, K., Tulin, A. V., & Zaret, K. S. (2009) · Genes & Development

Genomics and Chromatin DynamicsDiffusion and Search Dynamics

Cited by 221

Repression by Groucho/TLE/Grg Proteins: Genomic Site Recruitment Generates Compacted Chromatin In Vitro and Impairs Activator Binding In Vivo

Sekiya, T., & Zaret, K. S. (2007) · Molecular Cell

Genomics and Chromatin DynamicsEpigenetics and DNA Methylation

Cited by 173

Extracellular signals that regulate liver transcription factors during hepatic differentiation in vitro.

Liu, J. K., DiPersio, C. M., & Zaret, K. S. (1991) · Molecular and Cellular Biology

Liver physiology and pathologyGenomics and Chromatin Dynamics

Cited by 168

Two-Parameter Mobility Assessments Discriminate Diverse Regulatory Factor Behaviors in Chromatin

Lerner, J., Gomez-Garcia, P. A., McCarthy, R. L., Liu, Z., Lakadamyali, M., & Zaret, K. S. (2020) · Molecular Cell

Genomics and Chromatin DynamicsDiffusion and Search Dynamics

Cited by 110

Chromatin scanning by dynamic binding of pioneer factors

Zaret, K. S., Lerner, J., & Iwafuchi-Doi, M. (2016) · Molecular Cell

Genomics and Chromatin DynamicsDiffusion and Search Dynamics

Cited by 68

Polycomb Repressive Complex 2 Proteins EZH1 and EZH2 Regulate Timing of Postnatal Hepatocyte Maturation and Fibrosis by Repressing Genes With Euchromatic Promoters in Mice

Grindheim, J. M., Nicetto, D., Donahue, G., & Zaret, K. S. (2019) · Gastroenterology

Liver physiology and pathologyEpigenetics and DNA Methylation

Cited by 35

Cellular reprogramming in vivo initiated by SOX4 pioneer factor activity

Katsuda, T., Sussman, J. H., Ito, K., Katznelson, A., Yuan, S., Takenaka, N., Li, J., Merrell, A. J., Cure, H., Li, Q., et al. (2024) · Nature Communications

Liver physiology and pathologyGenomics and Chromatin Dynamics

Cited by 33