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Cancer and the gut microbiota: An unexpected link
Open accessAbstract
Gut microbiota and its interactions with the host immune system play a role in oncogenesis and can alter the effectiveness of anticancer agents.
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“Among all tumors, GC is arguably the most intensely affected by gut bacteria owing to their spatial proximity, and their associations with the gut microbiome have been intensively investigated [93,94].”
From Bioinformatics Analysis and Validation of Potential Markers Associated with Prediction and Prognosis of Gastric Cancer (2024) · cites this paper as [93]
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Citations
Cites
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“A detailed description of the intestinal immune system is beyond the scope of this article and can be found in (2).”
BackgroundPromotion of Hepatocellular Carcinoma by the Intestinal Microbiota and TLR4
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Alleviating Cancer Drug Toxicity by Inhibiting a Bacterial Enzyme
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Metadata
- Authors
- Zitvogel, L., Galluzzi, L., Viaud, S., Vétizou, M., Daillère, R., Merad, M., & Kroemer, G.
- Affiliations
- Inserm (FR)
- Department of Oncological Sciences, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
- Corresponding author
- Zitvogel, Laurence
- Galluzzi, Lorenzo
- Venue
- Science Translational Medicine
- Published
- 2015-01-21
- Volume
- 7
- Issue
- 271
- Pages
- 271ps1-271ps1
- ISSN
- 1946-6234 (ISSN-L)
- 1946-6242
- PMC
- PMC4690201
- OpenAlex
- W2164536401
- Cited by
- 465
- References
- 32
- Citations by year
- 2026: 21 · 2025: 31 · 2024: 35 · 2023: 37 · 2022: 42 · 2021: 62 · 2020: 64 · 2019: 48 · 2018: 46 · 2017: 36 · 2016: 28 · 2015: 15
- FWCI
- 4.04
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Science Translational Medicine (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- Association pour la Recherche sur le Cancer (ARC)
- European Commission (ArtForce)
- European Research Council (ERC)
- Agence Nationale de la Recherche (ANR)
- AXA Chair for Longevity Research
- Fondation pour la Recherche Medicale (FRM)
- Ligue contre le Cancer
- Fondation de France
- Institut National du Cancer (INCa)
- Canceropole Ile-de-France
- Fondation Bettencourt-Schueller
- LabEx Immuno-Oncology
- Site de Recherche Integree sur le Cancer (SIRIC)
- Stratified Oncology Cell DNA Repair and Tumor Immune Elimination (SOCRATE)
- SIRIC Cancer Research and Personalized Medicine (CARPEM)
- Paris Alliance of Cancer Research Institutes (PACRI)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gut microbiota and health
- Life Sciences › Agricultural and Biological Sciences › Food Science › Probiotics and Fermented Foods
- Health Sciences › Dentistry › Periodontics › Oral microbiology and periodontitis research
- Keywords
- gut microbiota, cancer, carcinogenesis, tumor progression, host-microbe interactions, intestinal epithelium, host immune system, environmental factors, cancer therapy, microbiome manipulation
- MeSH terms
- Antineoplastic Agents, Humans, Neoplasms, Gastrointestinal Tract, Carcinogenesis, Microbiota, Dysbiosis
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