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Therapeutic Potential of Selenium in Glioblastoma

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SLC7A11 negatively associates with mismatch repair gene expression and endows glioblastoma cells sensitive to radiation under low glucose conditions

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Natural products targeting ferroptosis pathways in cancer therapy (Review)

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Tryptophan Metabolic Enzyme IL4I1 Inhibits Ferroptosis by Decreasing Ubiquitination of Nrf2 via I3P in Glioblastoma

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Gliomagenesis, Epileptogenesis, and Remodeling of Neural Circuits: Relevance for Novel Treatment Strategies in Low- and High-Grade Gliomas

Grimi, A., Bono, B., Lazzarin, S. M., Marcheselli, S., Pessina, F., & Riva, M. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25168953 · Cited by 13

AMPA Receptor Modulation in the Treatment of High-Grade Glioma: Translating Good Science into Better Outcomes

Radin, D. P. (2025) · Pharmaceuticals · doi:10.3390/ph18030384 · Cited by 12

Excitotoxic SLC7A11 Expression Is a Marker of Poor Glioblastoma Survival and a Potential Therapeutic Target

Zhang, R. R., Pointer, K. B., & Kuo, J. S. (2015) · Neurosurgery · doi:10.1227/01.neu.0000473809.76102.ee · Cited by 11

Pheomelanin molecular vibration is associated with mitochondrial ROS production in melanocytes and systemic oxidative stress and damage

Galván, I., Jorge, A., & Gil, M. G. (2017) · Integrative Biology · doi:10.1039/c7ib00107j · Cited by 11

SLC7A9 as a Potential Biomarker for Lymph Node Metastasis of Esophageal Squamous Cell Carcinoma

Baba, H., Kanda, M., Sawaki, K., Nakamura, S., Ueda, S., Shimizu, D., Koike, M., Kodera, Y., & Fujii, T. (2021) · Annals of Surgical Oncology · doi:10.1245/s10434-021-11001-1 · Cited by 11

Combating malignant astrocytes: Strategies mitigating tumor invasion

Umans, R. A., & Sontheimer, H. W. (2017) · Neuroscience Research · doi:10.1016/j.neures.2017.09.010 · Cited by 10

Aberrant neuronal differentiation is common in glioma but is associated neither with epileptic seizures nor with better survival

Beier, C. P., Rasmussen, T., Dahlrot, R. H., Tenstad, H. B., Aarø, J. S., Sørensen, M. F., Heimisdóttir, S. B., Sørensen, M. D., Svenningsen, P., Riemenschneider, M. J., et al. (2018) · Scientific Reports · doi:10.1038/s41598-018-33282-5 · Cited by 11

Investigation of Endogenous Retrovirus Sequences in the Neighborhood of Genes Up-regulated in a Neuroblastoma Model after Treatment with Hypoxia-Mimetic Cobalt Chloride

Brütting, C., Narasimhan, H., Hoffmann, F. A., Kornhuber, M. E., Staege, M. S., & Emmer, A. (2018) · Frontiers in Microbiology · doi:10.3389/fmicb.2018.00287 · Cited by 12

Implication of system xc− in neuroinflammation during the onset and maintenance of neuropathic pain

Beckers, P., do Nascimento, I. B., Charlier, M., Desmet, N., Massie, A., & Hermans, E. (2024) · Journal of Neuroinflammation · doi:10.1186/s12974-024-03112-9 · Cited by 13

Analysis of intraoperative human brain tissue transcriptome reveals putative risk genes and altered molecular pathways in glioma-related seizures

Feyissa, A. M., Carrano, A., Wang, X., Allen, M., Ertekin‐Taner, N., Dickson, D. W., Jentoft, M. E., Rosenfeld, S. S., Tatum, W. O., Ritaccio, A. L., et al. (2021) · Epilepsy Research · doi:10.1016/j.eplepsyres.2021.106618 · Cited by 13

Development of a novel disulfidptosis-related lncRNA signature for prognostic and immune response prediction in clear cell renal cell carcinoma

Wang, N., Hu, Y., Wang, S., Xu, Q., Jiao, X., Wang, Y., Yan, L., Cao, H., & Shao, F. (2024) · Scientific Reports · doi:10.1038/s41598-024-51197-2 · Cited by 9

Breaking Down Glioma-Microenvironment Crosstalk

Ramachandran, R., & Jeans, A. F. (2024) · The Neuroscientist · doi:10.1177/10738584241259773 · Cited by 11

Integrative Disulfidptosis‐Based Risk Assessment for Prognostic Stratification and Immune Profiling in Glioma

Niu, X., Li, G., Kahlert, U. D., Ding, L., Zheng, J., Li, C., Shi, W., Huang, L., & Yu, Z. (2025) · Journal of Cellular and Molecular Medicine · doi:10.1111/jcmm.70429 · Cited by 9

Therapeutic and prognostic values of ferroptosis signature in glioblastoma

Nedaeinia, R., Dianat‐Moghadam, H., Movahednasab, M., Khosroabadi, Z., Keshavarz, M., Amoozgar, Z., & Salehi, R. (2025) · International Immunopharmacology · doi:10.1016/j.intimp.2025.114597 · Cited by 9

The excitatory milieu in glioma: Mechanisms and therapeutic avenues

Khalili, B. F., Dixit, K., Kamson, D. O., Horbinski, C., Przybyla, D. J., Tate, M. C., Heimberger, A. B., Lukas, R. V., & Templer, J. W. (2025) · Neuro-Oncology · doi:10.1093/neuonc/noaf063 · Cited by 11

Innovative Therapeutic Strategies Targeting the Network Architecture of Glioblastoma

Beichert, J., Hoffmann, D. C., Winkler, F., & Ratliff, M. (2025) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-25-0018 · Cited by 11

Glioma‐induced peritumoral hyperexcitability in a pediatric glioma model

Chaunsali, L., Tewari, B. P., Gallucci, A., Thompson, E. G., Savoia, A., Feld, N., & Campbell, S. L. (2020) · Physiological Reports · doi:10.14814/phy2.14567 · Cited by 9

Merlin/NF2 regulates SLC7A11/xCT expression and cell viability under glucose deprivation at high cell density in glioblastoma cells

Yamaguchi, I., & Katoh, H. (2023) · The Journal of Biochemistry · doi:10.1093/jb/mvad105 · Cited by 8

Cystine/cysteine metabolism regulates the progression and response to treatment of triple‑negative breast cancer (Review)

Xiao, W., & Xu, C. (2024) · Oncology Letters · doi:10.3892/ol.2024.14654 · Cited by 8

Deciphering the Dialogue between Brain Tumors, Neurons, and Astrocytes

Westerlund, L. H., Bergström, C., Laakkonen, P., & Joncour, V. L. (2025) · American Journal Of Pathology · doi:10.1016/j.ajpath.2025.04.013 · Cited by 8

Highlights from the Literature

Bhat, K., Pope, W., Huse, J. T., Hegi, M. E., & Aldape, K. (2015) · Neuro-Oncology · doi:10.1093/neuonc/nov252

Excitotoxic SLC7A11 Expression Is a Marker of Poor Glioblastoma Survival and a Potential Therapeutic Target

Zhang, R. R., Pointer, K. B., & Kuo, J. S. (2015) · Neurosurgery · doi:10.1227/01.neu.0000473809.76102.ee · Cited by 11

Glioma, glutamate (SLC7A11) and seizures—a commentary

Santosh, V., & Palavalasa, S. (2017) · Annals of Translational Medicine · doi:10.21037/atm.2017.02.18 · Cited by 9

High expression of cystine–glutamate antiporter xCT (SLC7A11) is an independent biomarker for epileptic seizures at diagnosis in glioma

Sørensen, M. F., Heimisdóttir, S. B., Sørensen, M. D., Mellegaard, C. S., Wohlleben, H., Kristensen, B. W., & Beier, C. P. (2018) · Journal of Neuro-Oncology · doi:10.1007/s11060-018-2785-9 · Cited by 68

The role of glutamate transport and SLC7A11 expression in tumor-associate seizures and survival in patients with malignant gliomas

Keen, J. R., Swanger, S. A., Traynelis, S. F., & Olson, J. J. (2016) · Annals of Translational Medicine · doi:10.21037/atm.2016.10.23 · Cited by 1