Dendritic cell vaccines based on immunogenic cell death elicit danger signals and T cell–driven rejection of high-grade glioma

The cBio Cancer Genomics Portal: An Open Platform for Exploring Multidimensional Cancer Genomics Data

Cerami, E., Gao, J., Dogrusoz, U., Gross, B. E., Sumer, S. O., Aksoy, B. A., Jacobsen, A., Byrne, C. J., Heuer, M. L., Larsson, E., et al. (2012) · Cancer Discovery · doi:10.1158/2159-8290.cd-12-0095 · Cited by 17,455

The cancer genome atlas pan-cancer analysis project

The Cancer Genome Atlas Research Network, Weinstein, J. N., Collisson, E. A., Mills, G. B., Shaw, K. R. M., Ozenberger, B. A., Ellrott, K., Shmulevich, I., Sander, C., & Stuart, J. M. (2013) · Nature Genetics · doi:10.1038/ng.2764 · Cited by 9,092

Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial

Stupp, R., Hegi, M. E., Mason, W. P., van den Bent, M. J., TAPHOORN, M. J. B., Janzer, R. C., Ludwin, S. K., Allgeier, A., Fisher, B., Bélanger, K., et al. (2009) · The Lancet Oncology · doi:10.1016/s1470-2045(09)70025-7 · Cited by 7,980

Comprehensive genomic characterization defines human glioblastoma genes and core pathways

The Cancer Genome Atlas Research Network (2008) · Nature · doi:10.1038/nature07385 · Cited by 7,735

The Somatic Genomic Landscape of Glioblastoma

Brennan, C. W., Verhaak, R. G. W., McKenna, A., Campos, B., Noushmehr, H., Salama, S. R., Zheng, S., Chakravarty, D., Sanborn, J. Z., Berman, S. H., et al. (2013) · Cell · doi:10.1016/j.cell.2013.09.034 · Cited by 5,016

The immune contexture in human tumours: impact on clinical outcome

Fridman, W. H., Pagès, F., Sautès-Fridman, C., & Galon, J. (2012) · Nature reviews. Cancer · doi:10.1038/nrc3245 · Cited by 4,981

Spatiotemporal Dynamics of Intratumoral Immune Cells Reveal the Immune Landscape in Human Cancer

Bindea, G., Mlecnik, B., Tosolini, M., Kirilovsky, A., Waldner, M. J., Obenauf, A. C., Angell, H. K., Fredriksen, T., Lafontaine, L., Berger, A., et al. (2013) · Immunity · doi:10.1016/j.immuni.2013.10.003 · Cited by 4,455

Immunogenic Cell Death in Cancer Therapy

Kroemer, G., Galluzzi, L., Kepp, O., & Zitvogel, L. (2013) · Annual Review of Immunology · doi:10.1146/annurev-immunol-032712-100008 · Cited by 3,303

Calreticulin exposure dictates the immunogenicity of cancer cell death

Obeid, M., Tesniere, A., Ghiringhelli, F., Fimia, G. M., Apetoh, L., Perfettini, J.-L., Castedo, M., Mignot, G., Panaretakis, T., Casares, N., et al. (2007) · Nature Medicine · doi:10.1038/nm1523 · Cited by 3,216

The prognostic landscape of genes and infiltrating immune cells across human cancers

Gentles, A. J., Newman, A. M., Liu, C. L., Bratman, S. V., Feng, W., Kim, D., Nair, V. S., Xu, Y., Khuong, A., Hoang, C. D., et al. (2015) · Nature Medicine · doi:10.1038/nm.3909 · Cited by 3,163

The danger theory of immunity revisited

Kroemer, G., Montégut, L., Kepp, O., & Zitvogel, L. (2024) · Nature reviews. Immunology · doi:10.1038/s41577-024-01102-9 · Cited by 55

Enzyme-instructed and mitochondria-targeting peptide self-assembly to efficiently induce immunogenic cell death

Zheng, D., Liu, J., Xie, L., Wang, Y., Ding, Y., Peng, R., Cui, M., Wang, L., Zhang, Y., Zhang, C., et al. (2021) · Acta Pharmaceutica Sinica B · doi:10.1016/j.apsb.2021.07.005 · Cited by 51

Photodynamic therapy mediated immune therapy of brain tumors

Hirschberg, H., Berg, K., & Peng, Q. (2018) · Neuroimmunology and Neuroinflammation · doi:10.20517/2347-8659.2018.31 · Cited by 50

The Role of Myeloid Cells in GBM Immunosuppression

Lin, Y.-J., Wu, C. Y.-J., Wu, J. Y., & Lim, M. K. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.887781 · Cited by 53

Emerging Role of the Unfolded Protein Response in Tumor Immunosurveillance

Vanacker, H., Vetters, J., Moudombi, L., Caux, C., Janssens, S., & Michallet, M. (2017) · Trends in cancer · doi:10.1016/j.trecan.2017.05.005 · Cited by 50

Reinforcing the immunogenic cell death to enhance cancer immunotherapy efficacy

Yu, S., Xiao, H., Ma, L., Zhang, J., & Zhang, J. (2023) · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer · doi:10.1016/j.bbcan.2023.188946 · Cited by 47

Targeting malignant melanoma with physical plasmas

Pasqual-Melo, G., Gandhirajan, R. K., Stoffels, I., & Bekeschus, S. (2018) · Clinical Plasma Medicine · doi:10.1016/j.cpme.2018.03.001 · Cited by 47

DC vaccines loaded with glioma cells killed by photodynamic therapy induce Th17 anti-tumor immunity and provide a four-gene signature for glioma prognosis

Vedunova, M. V., Turubanova, V. D., Vershinina, O., Saviuk, M. O., Efimova, I., Mishchenko, T. A., Raedt, R., Vral, A., Vanhove, C., Korsakova, D., et al. (2022) · Cell Death and Disease · doi:10.1038/s41419-022-05514-0 · Cited by 49

A myeloid and lymphoid infiltrate in murine pancreatic tumors exposed to plasma-treated medium

Liedtke, K. R., Freund, E., Hackbarth, C., Heidecke, C.-D., Partecke, L.-I., & Bekeschus, S. (2018) · Clinical Plasma Medicine · doi:10.1016/j.cpme.2018.07.001 · Cited by 48

Metabolic Remodeling in Glioma Immune Microenvironment: Intercellular Interactions Distinct From Peripheral Tumors

Qiu, R., Zhong, Y., Li, Q., Li, Y., & Fan, H. (2021) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2021.693215 · Cited by 49

Photodynamic Modulation of Type 1 Interferon Pathway on Melanoma Cells Promotes Dendritic Cell Activation

Lamberti, M. J., Mentucci, F. M., Roselli, E., Araya, P., Rivarola, V. A., Vittar, N. B. R., & Maccioni, M. (2019) · Frontiers in Immunology · doi:10.3389/fimmu.2019.02614 · Cited by 45

Molecular Mechanisms of Anti-Neoplastic and Immune Stimulatory Properties of Oncolytic Newcastle Disease Virus

Schirrmacher, V. (2022) · Biomedicines · doi:10.3390/biomedicines10030562 · Cited by 45

Translocator protein-targeted photodynamic therapy for direct and abscopal immunogenic cell death in colorectal cancer

Xie, Q., Li, Z., Liu, Y., Zhang, D., Su, M., Niitsu, H., Lu, Y., Coffey, R. J., & Bai, M. (2021) · Acta Biomaterialia · doi:10.1016/j.actbio.2021.07.052 · Cited by 47

Advances and challenges: dendritic cell vaccination strategies for glioblastoma

Schaller, T. H., & Sampson, J. H. (2016) · Expert Review of Vaccines · doi:10.1080/14760584.2016.1218762 · Cited by 44

Autophagy-Dependent Secretion: Contribution to Tumor Progression

Keulers, T. G., Schaaf, M. B. E., & Rouschop, K. M. A. (2016) · Frontiers in Oncology · doi:10.3389/fonc.2016.00251 · Cited by 43

Induction of Immunogenic Cell Death by Photodynamic Therapy Mediated by Aluminum-Phthalocyanine in Nanoemulsion

Rodrigues, M. C., Júnior, W. T. D. S., Mundim, T., Vale, C. L. C., de Oliveira, J. V., Ganassin, R., Pacheco, T. J. A., Morais, J. A. V., Longo, J. P. F., Azevedo, R. B., et al. (2022) · Pharmaceutics · doi:10.3390/pharmaceutics14010196 · Cited by 43

Caspase-2 and oxidative stress underlie the immunogenic potential of high hydrostatic pressure-induced cancer cell death

Moserova, I. K., Truxová, I., Garg, A. D., Tomala, J., Agostinis, P., Cartron, P., Vosahlikova, S., Kovář, M., Špíšek, R., & Fucikova, J. P. (2016) · OncoImmunology · doi:10.1080/2162402x.2016.1258505 · Cited by 39

Photodynamic Therapy-Based Dendritic Cell Vaccination Suited to Treat Peritoneal Mesothelioma

Trempolec, N., Doix, B., Degavre, C., Brusa, D., Bouzin, C., Riant, O., & Féron, O. (2020) · Cancers · doi:10.3390/cancers12030545 · Cited by 41

Randomized Controlled Immunotherapy Clinical Trials for GBM Challenged

Gool, S. V., Makalowski, J., Fiore, S., Sprenger, T., Prix, L., Schirrmacher, V., & Stuecker, W. (2020) · Cancers · doi:10.3390/cancers13010032 · Cited by 40

Photodynamic Therapy-Induced Anti-Tumor Immunity: Influence Factors and Synergistic Enhancement Strategies

Chou, W., Sun, T., Peng, N., Wang, Z., Chen, D., Qiu, H., & Zhao, H. (2023) · Pharmaceutics · doi:10.3390/pharmaceutics15112617 · Cited by 40

Factors Affecting Photodynamic Therapy and Anti-Tumor Immune Response

Hamblin, M. R., & Abrahamse, H. (2020) · Anti-Cancer Agents in Medicinal Chemistry · doi:10.2174/1871520620666200318101037 · Cited by 39

Dying tumor cells-inspired vaccine for boosting humoral and cellular immunity against cancer

Qin, X., Yang, T., Xu, H., Zhang, R., Zhao, S., Kong, L., Yang, C., & Zhang, Z. (2023) · Journal of Controlled Release · doi:10.1016/j.jconrel.2023.05.044 · Cited by 37

Diamonds in the Rough: Harnessing Tumor-Associated Myeloid Cells for Cancer Therapy

Clappaert, E. J., Murgaski, A., Damme, H. V., Kiss, M., & Laoui, D. (2018) · Frontiers in Immunology · doi:10.3389/fimmu.2018.02250 · Cited by 37

Imiquimod Exerts Antitumor Effects by Inducing Immunogenic Cell Death and Is Enhanced by the Glycolytic Inhibitor 2-Deoxyglucose

Huang, S., Wang, S.-T., Chang, S.-H., Chuang, K.-C., Wang, H.-Y., Kao, J., Liang, S., Wu, C., Kao, S., Chen, Y., et al. (2020) · Journal of Investigative Dermatology · doi:10.1016/j.jid.2019.12.039 · Cited by 37

CD137L dendritic cells induce potent response against cancer-associated viruses and polarize human CD8+ T cells to Tc1 phenotype

Dharmadhikari, B., Nickles, E. P., Harfuddin, Z., Ishak, N. D. B., Zeng, Q., Bertoletti, A., & Schwarz, H. (2018) · Cancer Immunology Immunotherapy · doi:10.1007/s00262-018-2144-x · Cited by 37

Hydroxycoumarin OT-55 kills CML cells alone or in synergy with imatinib or Synribo: Involvement of ER stress and DAMP release

Mazumder, A., Lee, J., Talhi, O., Cerella, C., Chateauvieux, S., Gaigneaux, A., Hong, C. R., Kang, H. J., Lee, Y., Kim, K.-W., et al. (2018) · Cancer Letters · doi:10.1016/j.canlet.2018.07.041 · Cited by 36

Glioma: bridging the tumor microenvironment, patient immune profiles and novel personalized immunotherapy

Mishchenko, T. A., Turubanova, V. D., Gorshkova, E. N., Krysko, O., Vedunova, M. V., & Krysko, D. V. (2024) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1299064 · Cited by 41

Elucidating the Innate Immunological Effects of Mild Magnetic Hyperthermia on U87 Human Glioblastoma Cells: An In Vitro Study

Persano, S., Vicini, F., Poggi, A. D., Fernandez, J. L. C., Rizzo, G. M. R., Gavilán, H., Silvestri, N., & Pellegrino, T. (2021) · Pharmaceutics · doi:10.3390/pharmaceutics13101668 · Cited by 37

Immunogenic cell stress and death in the treatment of cancer

Pan, H., Liu, P., Zhao, L., Pan, Y., Mao, M., Kroemer, G., & Kepp, O. (2023) · Seminars in Cell and Developmental Biology · doi:10.1016/j.semcdb.2023.10.007 · Cited by 35

Strategies to Improve Vaccine Efficacy against Tuberculosis by Targeting Innate Immunity

Schaible, U. E., Linnemann, L. C., Redinger, N., Patin, E. C., & Dallenga, T. K. (2017) · Frontiers in Immunology · doi:10.3389/fimmu.2017.01755 · Cited by 35

Dendritic Cell Vaccines: A Promising Approach in the Fight against Ovarian Cancer

Caro, A. A., Deschoemaeker, S., Allonsius, L., Coosemans, A., & Laoui, D. (2022) · Cancers · doi:10.3390/cancers14164037 · Cited by 36

The Evolution of Tumor Microenvironment in Gliomas and Its Implication for Target Therapy

Hu, Y., Li, Z., Zhang, Y., Wu, Y. C., Liu, Z., Zeng, J., Hao, Z., Li, J., Ren, J., & Yao, M. (2023) · International Journal of Biological Sciences · doi:10.7150/ijbs.83531 · Cited by 37

Reinforced Immunogenic Endoplasmic Reticulum Stress and Oxidative Stress via an Orchestrated Nanophotoinducer to Boost Cancer Photoimmunotherapy

Yang, Z., Teng, Y., Lin, M. S., Peng, Y., Du, Y., Sun, Q., Gao, D., Yuan, Q., Zhou, Y. J., Yang, Y., et al. (2024) · ACS Nano · doi:10.1021/acsnano.3c13143 · Cited by 31

The impact of autophagy during the development and survival of glioblastoma

Simpson, J. E., & Gammoh, N. (2020) · Open Biology · doi:10.1098/rsob.200184 · Cited by 36

Spatiotemporal‐Controlled NIR‐II Immune Agonist Sensitizes Cancer Immunotherapy

Guo, S., Tang, D., Zhang, M., Yang, H., Zhang, T., Hu, B., Xu, C., Weng, Y., Shang, K., & Huang, Y. (2024) · Advanced Materials · doi:10.1002/adma.202400228 · Cited by 30

Advances in Liposome-Encapsulated Phthalocyanines for Photodynamic Therapy

Rak, J., Kabešová, M., Beneš, J., POUCKOVA, P., & Větvička, D. (2023) · Life · doi:10.3390/life13020305 · Cited by 30

Early memory differentiation and cell death resistance in T cells predicts melanoma response to sequential anti-CTLA4 and anti-PD1 immunotherapy

Vanmeerbeek, I., Borràs, D., Sprooten, J., Bechter, O. E., Tejpar, S., & Garg, A. D. (2021) · Genes and Immunity · doi:10.1038/s41435-021-00138-4 · Cited by 28

Photodynamic Therapy-Mediated Immune Responses in Three-Dimensional Tumor Models

Nkune, N. W., Simelane, N. W. N., Montaseri, H., & Abrahamse, H. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms222312618 · Cited by 29

Metronomic treatment in immunocompetent preclinical GL261 glioblastoma: effects of cyclophosphamide and temozolomide

Ferrer‐Font, L., Arias‐Ramos, N., Lope‐Piedrafita, S., Julià‐Sapé, M., Pumarola, M. B., Arús, C., & Candiota, A. P. (2017) · NMR in Biomedicine · doi:10.1002/nbm.3748 · Cited by 28

Synthesis and anticancer activity in vitro and in vivo evaluation of iridium(III) complexes on mouse melanoma B16 cells

Yuan, Y., Shi, C., Wu, X., Li, W., Huang, C., Liang, L., Chen, J., Wang, Y., & Liu, Y. (2022) · Journal of Inorganic Biochemistry · doi:10.1016/j.jinorgbio.2022.111820 · Cited by 26

Immune Microenvironment and Immunotherapies for Diffuse Intrinsic Pontine Glioma

Chen, Y., Zhao, C., Li, S., Wang, J., & Zhang, H. (2023) · Cancers · doi:10.3390/cancers15030602 · Cited by 28

Translational Prospects of ultrasound-mediated tumor immunotherapy: Preclinical advances and safety considerations

Xu, W., Zhang, X., Hu, X., Zhiyi, C., & Huang, P. (2019) · Cancer Letters · doi:10.1016/j.canlet.2019.06.017 · Cited by 27

High expression of stromal signatures correlated with macrophage infiltration, angiogenesis and poor prognosis in glioma microenvironment

Tian, Y., Ke, Y., & Ma, Y. (2020) · PeerJ · doi:10.7717/peerj.9038 · Cited by 27

Immune system activation by natural products and complex fractions: a network pharmacology approach in cancer treatment

Gomez‐Cadena, A., Barreto, A., Fioretino, S., & Jandus, C. (2020) · Cell Stress · doi:10.15698/cst2020.07.224 · Cited by 32

Multifunctional Nanosystems Powered Photodynamic Immunotherapy

Ma, Y., Xiao, F., Lu, C., & Wen, L. (2022) · Frontiers in Pharmacology · doi:10.3389/fphar.2022.905078 · Cited by 27

The Role of Immune Checkpoint Inhibition in the Treatment of Brain Tumors

Luksik, A. S., Maxwell, R., Garzón-Muvdi, T., & Lim, M. K. (2017) · Neurotherapeutics · doi:10.1007/s13311-017-0513-3 · Cited by 27

4-Acetylantroquinonol B from antrodia cinnamomea enhances immune function of dendritic cells against liver cancer stem cells

Li, T.-Y., & Chiang, B. (2018) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2018.11.101 · Cited by 27

Photodynamic Opening of the Blood–Brain Barrier and the Meningeal Lymphatic System: The New Niche in Immunotherapy for Brain Tumors

Semyachkina-Glushkovskaya, O. V., Terskov, A. V., Khorovodov, A. P., Telnova, V., Blokhina, I., Saranceva, E. I., & Kurths, J. (2022) · Pharmaceutics · doi:10.3390/pharmaceutics14122612 · Cited by 27

Dendritic cell-derived exosomes as anti-cancer cell-free agents: new insights into enhancing immunogenic effects

Redkin, T. S., & Turubanova, V. D. (2025) · Frontiers in Immunology · doi:10.3389/fimmu.2025.1586892 · Cited by 26

Regulation of Fas in response to bortezomib and epirubicin in colorectal cancer cells

Çaçan, E., & Özmen, Z. C. (2020) · Journal of Chemotherapy · doi:10.1080/1120009x.2020.1740389 · Cited by 25

Biomimetic Active Materials Guided Immunogenic Cell Death for Enhanced Cancer Immunotherapy

Huang, G., Liu, L., Pan, H., & Cai, L. (2022) · Small Methods · doi:10.1002/smtd.202201412 · Cited by 25

Coordination of stress, Ca 2+ , and immunogenic signaling pathways by PERK at the endoplasmic reticulum

van Vliet, A. R., Garg, A. D., & Agostinis, P. (2016) · Biological Chemistry · doi:10.1515/hsz-2016-0108 · Cited by 25

The CXCL16-CXCR6 axis in glioblastoma modulates T-cell activity in a spatiotemporal context

Chia, T.-Y., Billingham, L. K., Boland, L. K., Katz, J. L., Arrieta, V. A., Shireman, J. M., Rosas, A.-L., DeLay, S. L., Zilinger, K., Geng, Y., et al. (2024) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1331287 · Cited by 25

Dendritic Cell-Based Immunotherapy in Hot and Cold Tumors

Kang, B. H., & Lee, H. K. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23137325 · Cited by 27

Honokiol-enhanced cytotoxic T lymphocyte activity against cholangiocarcinoma cells mediated by dendritic cells pulsed with damage-associated molecular patterns

Jiraviriyakul, A., Songjang, W., Kaewthet, P., Tanawatkitichai, P., Bayan, P., & Pongcharoen, S. (2019) · World Journal of Gastroenterology · doi:10.3748/wjg.v25.i29.3941 · Cited by 24

Advances in therapeutic cancer vaccines: Harnessing immune adjuvants for enhanced efficacy and future perspectives

Ren, D., Xiong, S., Ren, Y., Yang, X., Zhao, X., Jin, J., Xu, M., Liang, T., Guo, L., & Weng, L. (2024) · Computational and Structural Biotechnology Journal · doi:10.1016/j.csbj.2024.04.054 · Cited by 23

Light-enhanced VEGF121/rGel: A tumor targeted modality with vascular and immune-mediated efficacy

Weyergang, A., Fremstedal, A. S. V., Skarpen, E., Peng, Q., Mohamedali, K. A., Eng, M. S., Cheung, L. H., Rosenblum, M. G., Waltenberger, J. L., & Berg, K. (2018) · Journal of Controlled Release · doi:10.1016/j.jconrel.2018.09.005 · Cited by 22

Bidirectional crosstalk between therapeutic cancer vaccines and the tumor microenvironment: Beyond tumor antigens

Zhang, S.-W., Wang, H., Ding, X., Xiao, Y.-L., Shao, Z.-M., You, C., Gu, Y., & Jiang, Y. (2022) · Fundamental Research · doi:10.1016/j.fmre.2022.03.009 · Cited by 23

A photodynamically sensitized dendritic cell vaccine that promotes the anti-tumor effects of anti-PD-L1 monoclonal antibody in a murine model of head and neck squamous cell carcinoma

Li, S., Wang, D., Cheng, J., Sun, J., Kalvakolanu, D. V., Zhao, X. B., Wang, D., You, Y., Zhang, L., & Yu, D. (2022) · Journal of Translational Medicine · doi:10.1186/s12967-022-03707-x · Cited by 22

Cell‐Derived Vesicles for Nanoparticles' Coating: Biomimetic Approaches for Enhanced Blood Circulation and Cancer Therapy

Rodrigues, C. F., Fernandes, N. F., de Melo‐Diogo, D., Correia, I. J., & Moreira, A. F. (2022) · Advanced Healthcare Materials · doi:10.1002/adhm.202201214 · Cited by 21

Th1-involved immune infiltrates improve neoadjuvant chemoradiotherapy response of esophageal squamous cell carcinoma

Yuan, J., Weng, Z., Tan, Z., Luo, K., Zhong, J., Xie, X., Qu, C., Lin, X., Yang, H., Wen, J., et al. (2022) · Cancer Letters · doi:10.1016/j.canlet.2022.215959 · Cited by 22

Synergy between TMZ and individualized multimodal immunotherapy to improve overall survival of IDH1 wild-type MGMT promoter-unmethylated GBM patients

Gool, S. V., Makalowski, J., Bitar, M., de Vliet, P. V., Schirrmacher, V., & Stuecker, W. (2022) · Genes and Immunity · doi:10.1038/s41435-022-00162-y · Cited by 21

Research Progress of Natural Product Photosensitizers in Photodynamic Therapy

Zhou, X., Ying, X., Wu, L., Liu, L., Wang, Y., He, Y., & Han, M. Y. (2024) · Planta Medica · doi:10.1055/a-2257-9194 · Cited by 20

Immunotherapy with subcutaneous immunogenic autologous tumor lysate increases murine glioblastoma survival

Belmans, J., Woensel, M. V., Creyns, B., Dejaegher, J., Bullens, D. M. A., & Gool, S. V. (2017) · Scientific Reports · doi:10.1038/s41598-017-12584-0 · Cited by 20

The “Yin and Yang” of Unfolded Protein Response in Cancer and Immunogenic Cell Death

Rufo, N., Yang, Y., Vleeschouwer, S. D., & Agostinis, P. (2022) · Cells · doi:10.3390/cells11182899 · Cited by 21

Role of Natural Products in Combating Cancer

Barreto, C., & Jandus, A. (2022) · Cancer Insight · doi:10.58567/ci01010003 · Cited by 19

The need for paradigm shift: prognostic significance and implications of standard therapy-related systemic immunosuppression in glioblastoma for immunotherapy and oncolytic virotherapy

Stepanenko, A. A., Sosnovtseva, A. O., Valikhov, M. P., Chernysheva, A. A., Abramova, O. V., Naumenko, V., & Chekhonin, V. P. (2024) · Frontiers in Immunology · doi:10.3389/fimmu.2024.1326757 · Cited by 20

Non-thermal plasma modulates cellular markers associated with immunogenicity in a model of latent HIV-1 infection

Mohamed, H., Clemen, R., Freund, E., Lackmann, J., Wende, K., Connors, J. R., Haddad, E. K., Dampier, W., Wigdahl, B. L., Miller, V., et al. (2021) · PLoS ONE · doi:10.1371/journal.pone.0247125 · Cited by 19

Combating Established Mouse Glioblastoma through Nicotinylated‐Liposomes‐Mediated Targeted Chemotherapy in Combination with Dendritic‐Cell‐Based Genetic Immunization

Saha, S., Yakati, V., Bhattacharya, D., Kompella, S., Kuncha, M., Chakravarty, S., Sistla, R., & Chaudhuri, A. (2017) · Advanced Biosystems · doi:10.1002/adbi.201600009 · Cited by 18

Editorial: Immunogenic Cell Death in Cancer: From Benchside Research to Bedside Reality

Garg, A. D., & Agostinis, P. (2016) · Frontiers in Immunology · doi:10.3389/fimmu.2016.00110 · Cited by 20

Bone Marrow: The Central Immune System

Schirrmacher, V. (2023) · Immuno · doi:10.3390/immuno3030019 · Cited by 18

Novel Foscan®-derived ring-fused chlorins for photodynamic therapy of cancer

Mata, A. I., Pereira, N. A. M., Cardoso, A. L., Nascimento, B. F. O., Piñeiro, M., Scháberle, F. A., Gomes-da-Silva, L. C., Brito, R. M. M., & Melo, T. M. V. D. P. E. (2023) · Bioorganic & Medicinal Chemistry · doi:10.1016/j.bmc.2023.117443 · Cited by 17

The Use of Toll-like Receptor 4 Agonist to Reshape the Immune Signature in Ovarian Cancer

VINDEVOGEL, E., Baert, T., Hoylandt, A. V., Verbist, G., Velde, G. V., Garg, A. D., Agostinis, P., Vergote, I. B., & Coosemans, A. (2016) · Anticancer Research · doi:10.21873/anticanres.11162 · Cited by 17

Enhancing antitumour immunity with photodynamic therapy

Selbo, P. K., & Korbelik, M. (2025) · Photochemical & Photobiological Sciences · doi:10.1007/s43630-025-00690-2 · Cited by 16

ROS Cocktails as an Adjuvant for Personalized Antitumor Vaccination?

Clemen, R., & Bekeschus, S. (2021) · Vaccines · doi:10.3390/vaccines9050527 · Cited by 16

Peripheral gene signatures reveal distinct cancer patient immunotypes with therapeutic implications for autologous DC-based vaccines

Hensler, M., Raková, J., Kašíková, L., Lanickova, T., Pasulka, J., Holicek, P., Hraška, M., Hrnciarova, T., Kadlecová, P., Schoenenberger, A., et al. (2022) · Oncoimmunology · doi:10.1080/2162402x.2022.2101596 · Cited by 15

Computed determination of the in vitro optimal chemocombinations of sphaeropsidin A with chemotherapeutic agents to combat melanomas

Ingels, A., Dinhof, C., Garg, A. D., Maddau, L., Masi, M., Evidente, A., Berger, W., Dejaegher, B., & Mathieu, V. (2017) · Cancer Chemotherapy and Pharmacology · doi:10.1007/s00280-017-3293-x · Cited by 16

Deciphering immune microenvironment and cell evasion mechanisms in human gliomas

Rafii, S., Kandoussi, S., Ghouzlani, A., Naji, O., Reddy, K. P., Sadiqi, R. U., & Badou, A. (2023) · Frontiers in Oncology · doi:10.3389/fonc.2023.1135430 · Cited by 15

Human dendritic cell subsets in the glioblastoma-associated microenvironment

Hu, X., Jiang, C., Gao, Y., & Xue, X. (2023) · Journal of Neuroimmunology · doi:10.1016/j.jneuroim.2023.578147 · Cited by 15

Targeting immunogenic cell death for glioma immunotherapy

Mishchenko, T. A., Turubanova, V. D., Gorshkova, E. N., Krysko, O., Vedunova, M. V., & Krysko, D. V. (2023) · Trends in cancer · doi:10.1016/j.trecan.2023.10.005 · Cited by 15

Intratumoral delivery of tumor antigen-loaded DC and tumor-primed CD4+ T cells combined with agonist α-GITR mAb promotes durable CD8+ T-cell-dependent antitumor immunity

Liu, Z., Hao, X., Zhang, Y., Zhang, J., Carey, C. D., Falo, L. D., Storkus, W. J., & You, Z. (2017) · OncoImmunology · doi:10.1080/2162402x.2017.1315487 · Cited by 15

Dendritic cell transfer for cancer immunotherapy

Zhao, L., Zhang, S., Kepp, O., Kroemer, G., & Liu, P. (2022) · International review of cytology · doi:10.1016/bs.ircmb.2022.03.003 · Cited by 14

Direct loading of CTL epitopes onto MHC class I complexes on dendritic cell surface in vivo

Wang, P., Dong, S., Zhao, P., He, X., & Chen, M. (2018) · Biomaterials · doi:10.1016/j.biomaterials.2018.08.008 · Cited by 14

Immunomodulatory Effects by Photodynamic Treatment of Glioblastoma Cells In Vitro

Rothe, F., Patties, I., Kortmann, R., & Glasow, A. (2022) · Molecules · doi:10.3390/molecules27113384 · Cited by 13

Gold standard assessment of immunogenic cell death induced by photodynamic therapy: From in vitro to tumor mouse models and anti-cancer vaccination strategies

Mishchenko, T. A., Balalaeva, I. V., Turubanova, V. D., Saviuk, M. O., Shilyagina, N. Y., Krysko, O., Vedunova, M. V., & Krysko, D. V. (2023) · Methods in cell biology · doi:10.1016/bs.mcb.2023.05.003 · Cited by 16

Spatial Regulation of Cancer-Associated Fibroblasts and Tumor Cells via pH-Responsive Bispecific Antibody Delivery for Enhanced Chemo-Immunotherapy Synergy

Liu, H., Yong, T., Zhang, X., Wei, Z., Bie, N., Xu, S., Zhang, X., Li, S., Zhang, J., Zhou, P., et al. (2025) · ACS Nano · doi:10.1021/acsnano.4c13277 · Cited by 13

Next-Generation Dendritic Cell-Based Vaccines for Leukemia Patients

Hoffmann, J., Schmitt, M. W., Ni, M., & Schmitt, A. (2017) · Immunotherapy · doi:10.2217/imt-2016-0116 · Cited by 13

Evaluation of cell surface reactive immuno-adjuvant in combination with immunogenic cell death inducing drug for in situ chemo-immunotherapy

Walters, A. A., Wang, J. T.-W., & Al‐Jamal, K. T. (2020) · Journal of Controlled Release · doi:10.1016/j.jconrel.2020.03.029 · Cited by 13

Protein-Confined Rotor Strategy for Quantum Yield Enhancement in Supramolecular Photosensitizers toward Sentinel Lymph Node-Targeted Photodynamic Immunoactivation

Qin, S., Cheng, X., Zhou, Z., Zhang, X., Chen, J., Xu, P., Wu, T. H., & Hu, Y. (2025) · ACS Nano · doi:10.1021/acsnano.5c04279 · Cited by 12

Dendritic cells in triple-negative breast cancer: From pathophysiology to therapeutic applications

Sebastião, A. I., Simões, G., Oliveira, F., Mateus, D., Falcão, A. C., Carrascal, M. A., Gomes, C. M. F., Neves, B. M., & Cruz, M. T. (2025) · Cancer Treatment Reviews · doi:10.1016/j.ctrv.2025.102884 · Cited by 14

Molecular Nanoarchitectonics of Natural Photosensitizers and Their Derivatives Nanostructures for Improved Photodynamic Therapy

Li, X., Liu, Y., Wu, L., & Zhao, J. (2023) · ChemMedChem · doi:10.1002/cmdc.202300599 · Cited by 12

In Vitro Generation of Murine Dendritic Cells for Cancer Immunotherapy: An Optimized Protocol

Baert, T., Garg, A. D., VINDEVOGEL, E., Hoylandt, A. V., Verbist, G., Agonistinis, P., Vergote, I. B., & Coosemans, A. (2016) · Anticancer Research · doi:10.21873/anticanres.11163 · Cited by 12

Decoding cancer cell death-driven immune cell recruitment: An in vivo method for site-of-vaccination analyses

Fang, S., Agostinis, P., Salvén, P., & Garg, A. D. (2019) · Methods in enzymology on CD-ROM/Methods in enzymology · doi:10.1016/bs.mie.2019.04.013 · Cited by 11

Unraveling of Functional Activity of Primary Hippocampal Neuron-Glial Networks in Photodynamic Therapy Based on Tetracyanotetra(aryl)porphyrazines

Saviuk, M. O., Turubanova, V. D., Mishchenko, T. A., Lermontova, S. A., Klapshina, L. G., Krysko, D. V., & Vedunova, M. V. (2022) · Cells · doi:10.3390/cells11071212 · Cited by 11

Uncovering the immunotherapeutic cycle initiated by p19Arf and interferon-β gene transfer to cancer cells: An inducer of immunogenic cell death

Medrano, R. F. V., Hunger, A., Catani, J. P. P., & Strauss, B. E. (2017) · OncoImmunology · doi:10.1080/2162402x.2017.1329072 · Cited by 11

Collagen I enhances the efficiency and anti-tumor activity of dendritic-tumor fusion cells

He, J., Zheng, R., Zhang, Z., Tan, J., Zhou, C., Zhang, G., Jiang, X., Sun, Q., Zhou, S., Zheng, D., et al. (2017) · OncoImmunology · doi:10.1080/2162402x.2017.1361094 · Cited by 11

Self-Assembling Nanoparticles Orchestrate Cuproptosis-Immunotherapy Synergy to Suppress Postoperative Glioma Recurrence

Zhang, C., Hou, S., Hu, B., Wu, Z., Li, X., Dong, Y., Shi, X., Wang, S., Wang, Y., Sun, Z., et al. (2025) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.5c19127 · Cited by 10

Dendritic cell immunotherapy versus bevacizumab plus irinotecan in recurrent malignant glioma patients: a survival gain analysis

Artene, Ş.-A., Turcu-Ştiolică, A., Hartley, R., Ciurea, M. E., Daianu, O., Brindusa, C., Alexandru, O., Tătăranu, L. G., Purcaru, Ş. O., & Dricu, A. (2016) · OncoTargets and Therapy · doi:10.2147/ott.s112842 · Cited by 11

Perioperative corticosteroid treatment impairs tumor-infiltrating dendritic cells in patients with newly diagnosed adult-type diffuse gliomas

Carenza, C., Franzese, S., Castagna, A., Terzoli, S., Simonelli, M., Persico, P., Bello, L., Nibali, M. C., Pessina, F., Kunderfranco, P., et al. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2022.1074762 · Cited by 11

Next-generation immunogenic dendritic cell vaccines achieve a danger signaling and T cell-driven eradication of high-grade glioma

Garg, A., Vandenberk, L., Koks, C., Verschuere, T., Gool, S. V., & Agostinis, P. (2016) · Klinische Pädiatrie · doi:10.1055/s-0036-1593558

Irradiation of necrotic tumor cells used to pulse dendritic cells (DCs) potentiates DC vaccine-induced anti-tumor immunity in a mouse model of high-grade glioma

Vandenberk, L., Garg, A. D., Agostinis, P., Verschuere, T., Koks, C., Vleeschouwer, S. D., & Gool, S. V. (2014) · Journal for ImmunoTherapy of Cancer · doi:10.1186/2051-1426-2-s3-p163 · Cited by 1

Targeting immunogenic cell death for glioma immunotherapy

Mishchenko, T. A., Turubanova, V. D., Gorshkova, E. N., Krysko, O., Vedunova, M. V., & Krysko, D. V. (2023) · Trends in cancer · doi:10.1016/j.trecan.2023.10.005 · Cited by 15

Immunogene op oxidatietherapie-gebaseerde tweede generatie dendritische celvaccins voor de behandeling van hooggradige gliomen

Vandenberk, L. (2016) · Lirias

Approaches to Improve Efficiency of Dendritic Cell-based Therapy of High Grade Gliomas

Chistiakov, D. A., Chekhonin, I. V., Gurina, O. I., Bobryshev, Y. V., & Chekhonin, V. P. (2016) · Current Pharmaceutical Design · doi:10.2174/1381612822666160719110618 · Cited by 7