The DOI matches its Crossref record; 12 of the 12 references it cites were found in a registry or an index.
Interplay of impermeability and chromosomal beta-lactamase activity in imipenem-resistant Pseudomonas aeruginosa
Open accessAbstract
Mutational loss of the D2 porin causes imipenem resistance in Pseudomonas aeruginosa. It was found that this mechanism could function only when the chromosomal beta-lactamase was expressed. Mutants lacking both the beta-lactamase and the D2 porin were almost as susceptible as those that lacked the beta-lactamase but retained the porin. Thus, imipenem resistance reflected an interplay of the enzyme and impermeability, not either factor alone. These findings suggest that the activity of a carbapenem more beta-lactamase stable than imipenem should be less affected by the porin loss. Meropenem approached this behavior.
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Cites
PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT
Lowry, O., Rosebrough, N., Farr, A. L., & Randall, R. (1951) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)52451-6 · Cited by 317,331
The β-Lactamases of Gram-Negative Bacteria and their Possible Physiological Role
Richmond, M. H., & Sykes, R. B. (1973) · Advances in Microbial Physiology · doi:10.1016/s0065-2911(08)60376-8 · Cited by 690
Outer membrane of Pseudomonas aeruginosa: heat- 2-mercaptoethanol-modifiable proteins
Hancock, R. E., & Carey, A. M. (1979) · Journal of Bacteriology · doi:10.1128/jb.140.3.902-910.1979 · Cited by 425
Characterization of beta-lactamases
Bush, K. (1989) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.33.3.259 · Cited by 305
Trias, J., & Nikaido, H. (1990) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.34.1.52 · Cited by 291
Emergence of Resistance to Imipenem During Therapy for Pseudomonas aeruginosa Infections
Quinn, J. P., Dudek, E. J., DiVincenzo, C. A., Lucks, D. A., & Lerner, S. A. (1986) · Journal of Infectious Diseases · doi:10.1093/infdis/154.2.289 · Cited by 276
Classification of beta-lactamases: groups 1, 2a, 2b, and 2b'
Bush, K. (1989) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.33.3.264 · Cited by 211
Nikaido, H., & Normark, S. (1987) · Molecular Microbiology · doi:10.1111/j.1365-2958.1987.tb00523.x · Cited by 180
Livermore, D. M., & Yang, Y.-J. (1987) · The Journal of Infectious Diseases · doi:10.1093/infdis/155.4.775 · Cited by 101
Self-citationThe acyl-enzyme mechanism of β-lactamase action. The evidence for class C β-lactamases
Knott-Hunziker, V., Petursson, S., Waley, S. G., Jaurin, B., & Grundström, T. (1982) · Biochemical Journal · doi:10.1042/bj2070315 · Cited by 96
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Three Decades of β-Lactamase Inhibitors
Drawz, S. M., & Bonomo, R. A. (2010) · Clinical Microbiology Reviews · doi:10.1128/cmr.00037-09 · Cited by 1,709
Pseudomonas aeruginosa – a phenomenon of bacterial resistance
Strateva, T., & Yordanov, D. (2009) · Journal of Medical Microbiology · doi:10.1099/jmm.0.009142-0 · Cited by 803
Osano, E., Arakawa, Y., Wacharotayankun, R., Ohta, M., Horii, T., Ito, H., Yoshimura, F., & Kato, N. (1994) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.38.1.71 · Cited by 440
Quale, J., Bratu, S., Gupta, J., & Landman, D. (2006) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.50.5.1633-1641.2006 · Cited by 409
Detection of Pseudomonas aeruginosa Producing Metallo-β-Lactamases in a Large Centralized Laboratory
Pitout, J. D. D., Gregson, D. B., Poirel, L., McClure, J.-A., Le, P., & Church, D. L. (2005) · Journal of Clinical Microbiology · doi:10.1128/jcm.43.7.3129-3135.2005 · Cited by 331
Metadata
- Authors
- Livermore, D. M.
- Venue
- Antimicrobial Agents and Chemotherapy
- Publisher
- American Society for Microbiology
- Published
- 1992-09
- Volume
- 36
- Issue
- 9
- Pages
- 2046-2048
- ISSN
- 0066-4804 (ISSN-L)
- 1098-6596
- OpenAlex
- W2112059463
- Cited by
- 288
- References
- 12
- FWCI
- 5.86
- Type
- journal article
- Language
- en
- Open access
- green
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- Livermore, D. M. (1992). Interplay of impermeability and chromosomal beta-lactamase activity in imipenem-resistant Pseudomonas aeruginosa. Antimicrobial Agents and Chemotherapy. https://doi.org/10.1128/aac.36.9.2046
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
