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Cited by 398

The DOI matches its Crossref record; 133 of the 133 references it cites were found in a registry or an index.

Overview of medically important antifungal azole derivatives

Open access
Fromtling, R A·1988·Clinical Microbiology Reviews

Abstract

Fungal infections are a major burden to the health and welfare of modern humans. They range from simply cosmetic, non-life-threatening skin infections to severe, systemic infections that may lead to significant debilitation or death. The selection of chemotherapeutic agents useful for the treatment of fungal infections is small. In this overview, a major chemical group with antifungal activity, the azole derivatives, is examined. Included are historical and state of the art information on the in vitro activity, experimental in vivo activity, mode of action, pharmacokinetics, clinical studies, and uses and adverse reactions of imidazoles currently marketed (clotrimazole, miconazole, econazole, ketoconazole, bifonazole, butoconazole, croconazole, fenticonazole, isoconazole, oxiconazole, sulconazole, and tioconazole) and under development (aliconazole and omoconazole), as well as triazoles currently marketed (terconazole) and under development (fluconazole, itraconazole, vibunazole, alteconazole, and ICI 195,739).

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Cites

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Metadata

Authors
Fromtling, R. A.
Venue
Clinical Microbiology Reviews
Published
1988-04
Volume
1
Issue
2
Pages
187-217
ISSN
  • 0893-8512 (ISSN-L)
  • 1098-6618
OpenAlex
W1956991203
Cited by
398
References
133
FWCI
12.99
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: Overview of medically important antifungal azole derivatives. https://app.cochat.ai/papers/10.1128/cmr.1.2.187
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Fromtling, R. A. (1988). Overview of medically important antifungal azole derivatives. Clinical Microbiology Reviews. https://doi.org/10.1128/cmr.1.2.187

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.