Novel Bilobe Components in Trypanosoma brucei Identified Using Proximity-Dependent Biotinylation

Science

(2023) · doi:10.1126/science · Cited by 6,063 · see citing works

Adult sibling experience, roles, relationshhips and future concerns - a review of the literature in learning disabilities

(1996) · Institutional Research Information System University of Turin (University of Turin) · doi:10.1111/j · Cited by 5,486 · see citing works

A promiscuous biotin ligase fusion protein identifies proximal and interacting proteins in mammalian cells

Roux, K. J., Kim, D. I., Raida, M., & Burke, B. (2012) · Journal of Cell Biology · doi:10.1083/jcb.201112098 · Cited by 2,416 · see citing works

A tightly regulated inducible expression system for conditional gene knock-outs and dominant-negative genetics in Trypanosoma brucei

Wirtz, E., Leal, S., Ochatt, C. M., & Cross, G. (1999) · Molecular and Biochemical Parasitology · doi:10.1016/s0166-6851(99)00002-x · Cited by 1,381 · see citing works

TriTrypDB: a functional genomic resource for the Trypanosomatidae

Aslett, M. A., Aurrecoechea, C., Berriman, M., Brestelli, J. E., Brunk, B. P., Carrington, M., Depledge, D. P., Fischer, S., Gajria, B., Gao, X., et al. (2009) · Nucleic Acids Research · doi:10.1093/nar/gkp851 · Cited by 988 · see citing works

Flagellar motility is required for the viability of the bloodstream trypanosome

Broadhead, R., Dawe, H. R., Farr, H., Griffiths, S. J., Hart, S. R., Portman, N., Shaw, M. K., Ginger, M. L., Gaskell, S. J., McKean, P. G., et al. (2006) · Nature · doi:10.1038/nature04541 · Cited by 488 · see citing works

High-throughput phenotyping using parallel sequencing of RNA interference targets in the African trypanosomePreprint

Alsford, S., Turner, D., Obado, S. O., Sánchez‐Flores, A., Glover, L., Berriman, M., Hertz‐Fowler, C., & Horn, D. (2011) · Genome Research · doi:10.1101/gr.115089.110 · Cited by 470 · see citing works

On the surface coat and flagellar adhesion in trypanosomes

Vickerman, K. (1969) · Journal of Cell Science · doi:10.1242/jcs.5.1.163 · Cited by 438 · see citing works

The cell division cycle of Trypanosoma brucei brucei : timing of event markers and cytoskeletal modulations

Sherwin, T., & Gull, K. (1989) · Philosophical transactions of the Royal Society of London. Series B, Biological sciences · doi:10.1098/rstb.1989.0037 · Cited by 352 · see citing works

Microtubule polarity and dynamics in the control of organelle positioning, segregation, and cytokinesis in the trypanosome cell cycle.

Robinson, D. R., Sherwin, T., Ploubidou, A., Byard, E. H., & Keith Gull, B. (1995) · The Journal of Cell Biology · doi:10.1083/jcb.128.6.1163 · Cited by 320 · see citing works

The Cytoskeleton of Trypanosomatid Parasites

Gull, K. (1999) · Annual Review of Microbiology · doi:10.1146/annurev.micro.53.1.629 · Cited by 307 · see citing works

Kinetics of endocytosis and recycling of the GPI-anchored variant surface glycoprotein inTrypanosoma brucei

Engstler, M., Thilo, L., Weise, F., Grünfelder, C. G., Schwarz, H., Boshart, M., & Overath, P. (2004) · Journal of Cell Science · doi:10.1242/jcs.00938 · Cited by 208 · see citing works

Three-dimensional cellular architecture of the flagellar pocket and associated cytoskeleton in trypanosomes revealed by electron microscope tomography

Lacomble, S., Vaughan, S., Gadelha, C., Morphew, M. K., Shaw, M. K., McIntosh, J. R., & Keith Gull, B. (2009) · Journal of Cell Science · doi:10.1242/jcs.045740 · Cited by 196 · see citing works

Intraflagellar Transport and Functional Analysis of Genes Required for Flagellum Formation in Trypanosomes

Absalon, S., Blisnick, T., Kohl, L., Toutirais, G., Doré, G., Julkowska, D., Tavenet, A., & Bastin, P. (2007) · Molecular Biology of the Cell · doi:10.1091/mbc.e07-08-0749 · Cited by 187 · see citing works

Function of a conserved sequence motif in biotin holoenzyme synthetases

Kwon, K., & Beckett, D. (2000) · Protein Science · doi:10.1110/ps.9.8.1530 · Cited by 134 · see citing works

Biogenesis of the Trypanosome Endo-Exocytotic Organelle Is Cytoskeleton Mediated

Bonhivers, M., Nowacki, S., Landrein, N., & Robinson, D. R. (2008) · PLoS Biology · doi:10.1371/journal.pbio.0060105 · Cited by 133 · see citing works

Golgi Duplication in Trypanosoma brucei Requires Centrin2

He, C. Y., Pypaert, M., & Warren, G. W. (2005) · Science · doi:10.1126/science.1119969 · Cited by 132 · see citing works

A Repetitive Protein Essential for the Flagellum Attachment Zone Filament Structure and Function in Trypanosoma brucei

Vaughan, S., Kohl, L., Ngai, I., Wheeler, R. J., & Keith Gull, B. (2007) · Protist · doi:10.1016/j.protis.2007.08.005 · Cited by 127 · see citing works

The Enzymatic Synthesis of Holotranscarboxylase from Apotranscarboxylase and (+)-Biotin

Lane, M. D., Young, D. L., & Lynen, F. (1964) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)93825-1 · Cited by 112 · see citing works

A coiled-coil- and C2-domain-containing protein is required for FAZ assembly and cell morphology in Trypanosoma brucei

Zhou, Q., Liu, B., Sun, Y., & He, C. Y. (2011) · Journal of Cell Science · doi:10.1242/jcs.087676 · Cited by 92 · see citing works

Basal body movements orchestrate membrane organelle division and cell morphogenesis in Trypanosoma brucei

Lacomble, S., Vaughan, S., Gadelha, C., Morphew, M. K., Shaw, M. K., McIntosh, J. R., & Keith Gull, B. (2010) · Journal of Cell Science · doi:10.1242/jcs.074161 · Cited by 91 · see citing works

Host–parasite interactions and trypanosome morphogenesis: a flagellar pocketful of goodies

Gull, K. (2003) · Current Opinion in Microbiology · doi:10.1016/s1369-5274(03)00092-4 · Cited by 82 · see citing works

Targeted and proximity-dependent promiscuous protein biotinylation by a mutant Escherichia coli biotin protein ligase

Cronan, J. E. (2005) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2005.03.017 · Cited by 80 · see citing works

A Comparative Proteomic Analysis Reveals a New Bi-Lobe Protein Required for Bi-Lobe Duplication and Cell Division in Trypanosoma brucei

Zhou, Q., Gheiratmand, L., Chen, Y., Lim, T. K., Zhang, J., Li, S., Xia, N., Liu, B., Lin, Q., & He, C. Y. (2010) · PLoS ONE · doi:10.1371/journal.pone.0009660 · Cited by 70 · see citing works

Combining RNA Interference Mutants and Comparative Proteomics to Identify Protein Components and Dependences in a Eukaryotic Flagellum

Portman, N., Lacomble, S., Thomas, B., McKean, P. G., & Keith Gull, B. (2008) · Journal of Biological Chemistry · doi:10.1074/jbc.m808859200 · Cited by 65 · see citing works

Morphology of the Trypanosome Bilobe, a Novel Cytoskeletal Structure

Esson, H. J., Morriswood, B., Yavuz, S., Vidilaseris, K., Dong, G., & Warren, G. (2012) · Eukaryotic Cell · doi:10.1128/ec.05287-11 · Cited by 64 · see citing works

Centrin4 coordinates cell and nuclear division inT. brucei

Shi, J., Franklin, J. B., Yelinek, J. T., Ebersberger, I., Warren, G., & He, C. Y. (2008) · Journal of Cell Science · doi:10.1242/jcs.030643 · Cited by 64 · see citing works

The bilobe structure of Trypanosoma brucei contains a MORN-repeat protein

Morriswood, B., He, C. Y., Sealey‐Cardona, M., Yelinek, J. T., Pypaert, M., & Warren, G. (2009) · Molecular and Biochemical Parasitology · doi:10.1016/j.molbiopara.2009.05.001 · Cited by 60 · see citing works

Structure-Function Analysis of Dynein Light Chain 1 Identifies Viable Motility Mutants in Bloodstream-Form Trypanosoma brucei

Ralston, K. S., Kisalu, N. K., & Hill, K. L. (2011) · Eukaryotic Cell · doi:10.1128/ec.00298-10 · Cited by 41 · see citing works

The Trypanosoma brucei AIR9‐like protein is cytoskeleton‐associated and is required for nucleus positioning and accurate cleavage furrow placement

May, S. F., Peacock, L., Costa, C. I. C. A., Gibson, W. C., Tetley, L., Robinson, D. R., & Hammarton, T. C. (2012) · Molecular Microbiology · doi:10.1111/j.1365-2958.2012.08008.x · Cited by 33 · see citing works

Electron microscopy observations on Trypanosoma brucei: Freeze-cleaving and thin-sectioning study of the apical part of the flagellar pocket

Henley, G. L., Lee, C. M., & Takeuchi, A. (1978) · Parasitology Research · doi:10.1007/bf00390368 · Cited by 19 · see citing works

An interplay between Centrin2 and Centrin4 on the bi‐lobed structure in Trypanosoma brucei

Wang, M., Gheiratmand, L., & He, C. Y. (2012) · Molecular Microbiology · doi:10.1111/j.1365-2958.2012.07998.x · Cited by 14 · see citing works

Untitled work

Barbero (2014) · doi:10.1016/j · Cited by 1 · see citing works

Effects of step-wise increases in dietary carbohydrate on circulating saturated fatty acids and palmitoleic acid in adults with metabolic syndrome

(2014) · Institutional Repository University of Antioquia (University of Antioquia) · doi:10.1371/journal.pone

Efficient proximity labeling in living cells and organisms with TurboID

Branon, T. C., Bosch, J. A., Sanchez, A. D., Udeshi, N. D., Svinkina, T., Carr, S. A., Feldman, J. L., Perrimon, N., & Ting, A. Y. (2018) · Nature Biotechnology · doi:10.1038/nbt.4201 · Cited by 2,174 · see citing works

An improved smaller biotin ligase for BioID proximity labeling

Kim, D. I., Jensen, S. C., Noble, K. A., Birendra, K. C., Roux, K. H., Motamedchaboki, K., & Roux, K. J. (2016) · Molecular Biology of the Cell · doi:10.1091/mbc.e15-12-0844 · Cited by 822 · see citing works

Deciphering molecular interactions by proximity labeling

Qin, W., Cho, K. F., Cavanagh, P. E., & Ting, A. Y. (2021) · Nature Methods · doi:10.1038/s41592-020-01010-5 · Cited by 671 · see citing works

Probing nuclear pore complex architecture with proximity-dependent biotinylation

Kim, D. I., KC, B., Zhu, W., Motamedchaboki, K., Doye, V., & Roux, K. J. (2014) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1406459111 · Cited by 560 · see citing works

Spatially resolved proteomic mapping in living cells with the engineered peroxidase APEX2

Hung, V., Udeshi, N. D., Lam, S. S., Loh, K. H., Cox, K. J., Pedram, K., Carr, S. A., & Ting, A. Y. (2016) · Nature Protocols · doi:10.1038/nprot.2016.018 · Cited by 541 · see citing works

BioID: A Screen for Protein‐Protein Interactions

Roux, K. J., Kim, D. I., & Burke, B. E. (2013) · Current Protocols in Protein Science · doi:10.1002/0471140864.ps1923s74 · Cited by 505 · see citing works

BioID: A Screen for Protein‐Protein Interactions

Roux, K. J., Kim, D. I., Burke, B. E., & May, D. G. (2018) · Current Protocols in Protein Science · doi:10.1002/cpps.51 · Cited by 334 · see citing works

Filling the Void: Proximity-Based Labeling of Proteins in Living Cells

Kim, D. I., & Roux, K. J. (2016) · Trends in Cell Biology · doi:10.1016/j.tcb.2016.09.004 · Cited by 288 · see citing works

Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes

Lambert, J., Tucholska, M., Go, C. D., Knight, J. D. R., & Gingras, A. (2014) · Journal of Proteomics · doi:10.1016/j.jprot.2014.09.011 · Cited by 253 · see citing works

Proximity Interactions among Centrosome Components Identify Regulators of Centriole Duplication

Firat‐Karalar, E. N., Rauniyar, N., Yates, J. R., & Stearns, T. (2014) · Current Biology · doi:10.1016/j.cub.2014.01.067 · Cited by 194 · see citing works

Novel Components of the Toxoplasma Inner Membrane Complex Revealed by BioID

Chen, A. L., Kim, E. W., Toh, J. Y., Vashisht, A. A., Rashoff, A. Q., Van, C., Huang, A. S., Moon, A. S., Bell, H. N., Bentolila, L. A., et al. (2015) · mBio · doi:10.1128/mbio.02357-14 · Cited by 171 · see citing works

Meet the neighbors: Mapping local protein interactomes by proximity‐dependent labeling with BioID

Varnaitė, R., & MacNeill, S. A. (2016) · PROTEOMICS · doi:10.1002/pmic.201600123 · Cited by 167 · see citing works

Recent advances in proximity-based labeling methods for interactome mapping

Trinkle‐Mulcahy, L. (2019) · F1000Research · doi:10.12688/f1000research.16903.1 · Cited by 166 · see citing works

BioID as a Tool for Protein-Proximity Labeling in Living Cells

Sears, R. M., May, D. G., & Roux, K. J. (2019) · Methods in molecular biology · doi:10.1007/978-1-4939-9546-2_15 · Cited by 153 · see citing works

Transcriptome, proteome and draft genome of Euglena gracilis

Ebenezer, T. E., Zoltner, M., Burrell, A., Nenarokova, A., Vanclová, A. M. G. N., Prasad, B., Soukal, P., Santana‐Molina, C., O’Neill, E. C., Nankissoor, N. N., et al. (2019) · BMC Biology · doi:10.1186/s12915-019-0626-8 · Cited by 143 · see citing works

BioID identifies novel c-MYC interacting partners in cultured cells and xenograft tumors

Dingar, D., Kalkat, M., Chan, P.-K., Srikumar, T., Bailey, S. D., Tu, W. B., Coyaud, E., Ponzielli, R., Kolyar, M., Jurisica, I., et al. (2015) · Journal of Proteomics · doi:10.1016/j.jprot.2014.09.029 · Cited by 131 · see citing works

Protein Neighbors and Proximity Proteomics

Rees, J. S., Li, X.-W., Perrett, S., Lilley, K. S., & Jackson, A. P. (2015) · Molecular & Cellular Proteomics · doi:10.1074/mcp.r115.052902 · Cited by 119 · see citing works

Proximity‐dependent labeling methods for proteomic profiling in living cells: An update

Bosch, J. A., Chen, C., & Perrimon, N. (2020) · Wiley Interdisciplinary Reviews Developmental Biology · doi:10.1002/wdev.392 · Cited by 119 · see citing works

Systems-based proteomics to resolve the biology of Alzheimer’s disease beyond amyloid and tau

Rayaprolu, S., Higginbotham, L., Bagchi, P., Watson, C. M., Zhang, T., Levey, A. I., Rangaraju, S., & Seyfried, N. T. (2021) · Neuropsychopharmacology · doi:10.1038/s41386-020-00840-3 · Cited by 118 · see citing works

Integrative proteomics and bioinformatic prediction enable a high-confidence apicoplast proteome in malaria parasites

Boucher, M. J., Ghosh, S., Zhang, L., Lal, A., Jang, S. W., Ju, A., Zhang, S., Wang, X., Ralph, S. A., Zou, J., et al. (2018) · PLoS Biology · doi:10.1371/journal.pbio.2005895 · Cited by 112 · see citing works

The Flagellum Attachment Zone: ‘The Cellular Ruler’ of Trypanosome Morphology

Sunter, J. D., & Keith Gull, B. (2016) · Trends in Parasitology · doi:10.1016/j.pt.2015.12.010 · Cited by 105 · see citing works

Proteomic Mapping of Mitochondria in Living Cells via Spatially Restricted Enzymatic Tagging

Rhee, H.-W., Zou, P., Udeshi, N. D., Martell, J. D., Mootha, V. K., Carr, S. A., & Ting, A. Y. (2013) · Science · doi:10.1126/science.1230593 · Cited by 83 · see citing works

The development of proximity labeling technology and its applications in mammals, plants, and microorganisms

Guo, J., Guo, S., Lu, S., Gong, J., Wang, L., Ding, L., Chen, Q., & Liu, W. (2023) · Cell Communication and Signaling · doi:10.1186/s12964-023-01310-1 · Cited by 83 · see citing works

Evolutionary cell biology of chromosome segregation: insights from trypanosomes

Akiyoshi, B., & Keith Gull, B. (2013) · Open Biology · doi:10.1098/rsob.130023 · Cited by 80 · see citing works

Proteomic identification of novel cytoskeletal proteins associated with TbPLK, an essential regulator of cell morphogenesis inTrypanosoma brucei

McAllaster, M. R., Ikeda, K. N., Lozano-Núñez, A., Anrather, D., Unterwurzacher, V., Gossenreiter, T., Perry, J. A., Crickley, R., Mercadante, C. J., Vaughan, S., et al. (2015) · Molecular Biology of the Cell · doi:10.1091/mbc.e15-04-0219 · Cited by 76 · see citing works

A dynamic coordination of flagellum and cytoplasmic cytoskeleton assembly specifies cell morphogenesis in trypanosomes

Sunter, J. D., Varga, V., Dean, S., & Keith Gull, B. (2015) · Journal of Cell Science · doi:10.1242/jcs.166447 · Cited by 73 · see citing works

Proximity‐dependent labeling methods for proteomic profiling in living cells

Chen, C., & Perrimon, N. (2017) · Wiley Interdisciplinary Reviews Developmental Biology · doi:10.1002/wdev.272 · Cited by 72 · see citing works

Capturing the Asc1p/Receptor for Activated C Kinase 1 (RACK1) Microenvironment at the Head Region of the 40S Ribosome with Quantitative BioID in Yeast

Opitz, N., Schmitt, K., Hofer-Pretz, V., Neumann, B., Krebber, H., Braus, G. H., & Valerius, O. (2017) · Molecular & Cellular Proteomics · doi:10.1074/mcp.m116.066654 · Cited by 71 · see citing works

SINC, a type III secreted protein of Chlamydia psittaci, targets the inner nuclear membrane of infected cells and uninfected neighbors

Mojica, S. A., Hovis, K. M., Frieman, M. B., Tran, B. Q., Hsia, R., Ravel, J., Jenkins-Houk, C., Wilson, K. L., & Bavoil, P. M. (2015) · Molecular Biology of the Cell · doi:10.1091/mbc.e14-11-1530 · Cited by 67 · see citing works

Assembly and maintenance of the flagellum attachment zone filament in Trypanosoma brucei

Zhou, Q., Hu, H., He, C. Y., & Li, Z. (2015) · Journal of Cell Science · doi:10.1242/jcs.168377 · Cited by 60 · see citing works

Flagellar pocket restructuring through theLeishmanialife cycle involves a discrete flagellum attachment zone

Wheeler, R. J., Sunter, J. D., & Keith Gull, B. (2016) · Journal of Cell Science · doi:10.1242/jcs.183152 · Cited by 58 · see citing works

An EF-hand-containing Protein in Trypanosoma brucei Regulates Cytokinesis Initiation by Maintaining the Stability of the Cytokinesis Initiation Factor CIF1

Zhou, Q., Hu, H., & Li, Z. (2016) · Journal of Biological Chemistry · doi:10.1074/jbc.m116.726133 · Cited by 58 · see citing works

Probing mammalian centrosome structure using BioID proximity-dependent biotinylation

Firat‐Karalar, E. N., & Stearns, T. (2015) · Methods in cell biology · doi:10.1016/bs.mcb.2015.03.016 · Cited by 56 · see citing works

Identification of novel parasitophorous vacuole proteins in P. falciparum parasites using BioID

Khosh-Naucke, M., Becker, J., Mesén-Ramírez, P., Kiani, P., Birnbaum, J., Fröhlke, U., Jonscher, E., Schlüter, H., & Spielmann, T. (2017) · International Journal of Medical Microbiology · doi:10.1016/j.ijmm.2017.07.007 · Cited by 55 · see citing works

BioID Reveals Novel Proteins of the Plasmodium Parasitophorous Vacuole Membrane

Schnider, C. B., Bausch‐Fluck, D., Brühlmann, F., Heussler, V. T., & Burda, P. (2018) · mSphere · doi:10.1128/msphere.00522-17 · Cited by 55 · see citing works

Subcellular Transcriptomics and Proteomics: A Comparative Methods Review

Christopher, J. A., Geladaki, A., Dawson, C. S., Vennard, O. L., & Lilley, K. S. (2021) · Molecular & Cellular Proteomics · doi:10.1016/j.mcpro.2021.100186 · Cited by 48 · see citing works

The CIF1 protein is a master orchestrator of trypanosome cytokinesis that recruits several cytokinesis regulators to the cytokinesis initiation site

Zhou, Q., Tai, A., Pham, K. T. M., Hu, H., & Li, Z. (2018) · Journal of Biological Chemistry · doi:10.1074/jbc.ra118.004888 · Cited by 47 · see citing works

Identification of TOEFAZ1‐interacting proteins reveals key regulators of Trypanosoma brucei cytokinesis

Hilton, N. A., Sladewski, T. E., Perry, J. A., Pataki, Z., Sinclair, A. N., Muniz, R. S., Tran, H. L., Wurster, J. I., Seo, J., & de Graffenried, C. L. (2018) · Molecular Microbiology · doi:10.1111/mmi.13986 · Cited by 43 · see citing works

Marked by association: techniques for proximity-dependent labeling of proteins in eukaryotic cells

Roux, K. J. (2013) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-013-1287-3 · Cited by 43 · see citing works

Proximity Interactions among Basal Body Components in Trypanosoma brucei Identify Novel Regulators of Basal Body Biogenesis and Inheritance

Dang, H. Q., Zhou, Q., Rowlett, V. W., Hu, H., Lee, K. J., Margolin, W., & Li, Z. (2017) · mBio · doi:10.1128/mbio.02120-16 · Cited by 42 · see citing works

Interaction between the flagellar pocket collar and the hook complex via a novel microtubule-binding protein in Trypanosoma brucei

Albisetti, A., Florimond, C., Landrein, N., Vidilaseris, K., Eggenspieler, M., Lesigang, J., Dong, G., Robinson, D. R., & Bonhivers, M. (2017) · PLoS Pathogens · doi:10.1371/journal.ppat.1006710 · Cited by 42 · see citing works

Trypanosomatid Flagellar Pocket from Structure to Function

Halliday, C., Neto, A. L. C., Alcantara, C. D. L., Cunha‐e‐Silva, N. L., Vaughan, S., & Sunter, J. D. (2020) · Trends in Parasitology · doi:10.1016/j.pt.2020.11.005 · Cited by 41 · see citing works

Protein diversity in discrete structures at the distal tip of the trypanosome flagellum

Varga, V., Moreira-Leite, F. F., Portman, N., & Keith Gull, B. (2017) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1703553114 · Cited by 41 · see citing works

The endocytic activity of the flagellar pocket in Trypanosoma brucei is regulated by an adjacent phosphatidylinositol phosphate kinase

Demmel, L., Schmidt, K., Lucast, L. J., Havlicek, K., Zankel, A., Koestler, T., Reithofer, V., Camilli, P. V. D., & Warren, G. (2014) · Journal of Cell Science · doi:10.1242/jcs.146894 · Cited by 38 · see citing works

Flagellum attachment zone protein modulation and regulation of cell shape in Trypanosoma brucei life cycle transitions

Sunter, J. D., Benz, C., Harmer, J., Whipple, S., McKean, P. G., Keith Gull, B., Ginger, M. L., & Lukeš, J. (2015) · Journal of Cell Science · doi:10.1242/jcs.171645 · Cited by 38 · see citing works

A multi-adenylate cyclase regulator at the flagellar tip controls African trypanosome transmission

Bachmaier, S., Giacomelli, G., Calvo-Alvarez, E., Vieira, L. R., Van Den Abbeele, J., Aristodemou, A., Lorentzen, E., Gould, M. K., Brennand, A., Dupuy, J.-W., et al. (2022) · Nature Communications · doi:10.1038/s41467-022-33108-z · Cited by 38 · see citing works

Impact of inherent biases built into proteomic techniques: Proximity labeling and affinity capture compared

Moreira, C. M. D. N., Kelemen, C. D., Obado, S. O., Zahedifard, F., Zhang, N., Holetz, F., Gauglitz, L., Dallagiovanna, B., Field, M. C., Krämer, S., et al. (2022) · Journal of Biological Chemistry · doi:10.1016/j.jbc.2022.102726 · Cited by 36 · see citing works

SAS-4 Protein in Trypanosoma brucei Controls Life Cycle Transitions by Modulating the Length of the Flagellum Attachment Zone Filament

Hu, H., Zhou, Q., & Li, Z. (2015) · Journal of Biological Chemistry · doi:10.1074/jbc.m115.694109 · Cited by 35 · see citing works

New Insights into the Molecular Mechanisms of Mitosis and Cytokinesis in Trypanosomes

Zhou, Q., Hu, H., & Li, Z. (2014) · International review of cytology · doi:10.1016/b978-0-12-800097-7.00004-x · Cited by 35 · see citing works

BioID Identification of Lamin-Associated Proteins

Mehus, A. A., Anderson, R. H., & Roux, K. J. (2015) · Methods in enzymology on CD-ROM/Methods in enzymology · doi:10.1016/bs.mie.2015.08.008 · Cited by 35 · see citing works

Proximity-Dependent Biotin Identification (BioID) in Dictyostelium Amoebae

Batsios, P., Meyer, I., & Gräf, R. (2015) · Methods in enzymology on CD-ROM/Methods in enzymology · doi:10.1016/bs.mie.2015.09.007 · Cited by 35 · see citing works

A MORN Repeat Protein Facilitates Protein Entry into the Flagellar Pocket of Trypanosoma brucei

Morriswood, B., & Schmidt, K. (2015) · Eukaryotic Cell · doi:10.1128/ec.00094-15 · Cited by 34 · see citing works

Proteomic Analysis of the EWS-Fli-1 Interactome Reveals the Role of the Lysosome in EWS-Fli-1 Turnover

Elzi, D. J., Song, M., Hakala, K. W., Weintraub, S. T., & Shiio, Y. (2014) · Journal of Proteome Research · doi:10.1021/pr500387m · Cited by 34 · see citing works

Highly effective proximate labeling in <i>Drosophila</i>

Zhang, B., Zhang, Y., & Liu, J.-L. (2021) · G3 Genes|Genomes|Genetics · doi:10.1093/g3journal/jkab077 · Cited by 32 · see citing works

Form, Fabric, and Function of a Flagellum-Associated Cytoskeletal Structure

Morriswood, B. (2015) · Cells · doi:10.3390/cells4040726 · Cited by 32 · see citing works

A Toolbox for Efficient Proximity-Dependent Biotinylation in Zebrafish Embryos

Rosenthal, S. M., Misra, T., Abdouni, H. S., Branon, T. C., Ting, A. Y., Scott, I. C., & Gingras, A. (2021) · Molecular & Cellular Proteomics · doi:10.1016/j.mcpro.2021.100128 · Cited by 32 · see citing works

Polo-like kinase phosphorylation of bilobe-resident TbCentrin2 facilitates flagellar inheritance inTrypanosoma brucei

de Graffenried, C. L., Anrather, D., von Raußendorf, F., & Warren, G. (2013) · Molecular Biology of the Cell · doi:10.1091/mbc.e12-12-0911 · Cited by 31 · see citing works

Giant FAZ10 is required for flagellum attachment zone stabilization and furrow positioning in Trypanosoma brucei

Moreira, B. P., da Fonseca, C. K., Hammarton, T. C., & Baqui, M. M. A. (2017) · Journal of Cell Science · doi:10.1242/jcs.194308 · Cited by 31 · see citing works

BILBO1 Is a Scaffold Protein of the Flagellar Pocket Collar in the Pathogen Trypanosoma brucei

Florimond, C., Sahin, A., Vidilaseris, K., Dong, G., Landrein, N., Dacheux, D., Albisetti, A., Byard, E. H., Bonhivers, M., & Robinson, D. R. (2015) · PLoS Pathogens · doi:10.1371/journal.ppat.1004654 · Cited by 30 · see citing works

The Major Protein Arginine Methyltransferase in Trypanosoma brucei Functions as an Enzyme-Prozyme Complex

Kafková, L., Debler, E., Fisk, J. C., Jain, K., Clarke, S. G., & Read, L. K. (2016) · Journal of Biological Chemistry · doi:10.1074/jbc.m116.757112 · Cited by 29 · see citing works

Tubulin-binding cofactor C domain-containing protein TBCCD1 orchestrates cytoskeletal filament formation

Harmer, J., Harrison, S., Towers, K., Qi, X., Vaughan, S., McKean, P. G., & Ginger, M. L. (2013) · Journal of Cell Science · doi:10.1242/jcs.136515 · Cited by 28 · see citing works

In Vivo Proximity Labeling for the Detection of Protein–Protein and Protein–RNA Interactions

Beck, D. B., Narendra, V. K., Drury, W. J., Casey, R., Jansen, P. W. T. C., Yuan, Z., Garcia, B. A., Vermeulen, M., & Bonasio, R. (2014) · Journal of Proteome Research · doi:10.1021/pr500196b · Cited by 26 · see citing works

Exclusive expression of the Rab11 effector SH3TC2 in Schwann cells links integrin-α6 and myelin maintenance to Charcot-Marie-Tooth disease type 4C

Vijay, S., Chiu, M., Dacks, J., & Roberts, R. C. (2016) · Biochimica et Biophysica Acta · doi:10.1016/j.bbadis.2016.04.003 · Cited by 24 · see citing works

The unconventional kinetoplastid kinetochore: from discovery toward functional understanding

Akiyoshi, B. (2016) · Biochemical Society Transactions · doi:10.1042/bst20160112 · Cited by 26 · see citing works

Identifying Protein-Protein Associations at the Nuclear Envelope with BioID

Kim, D. I., Jensen, S. C., & Roux, K. J. (2016) · Methods in molecular biology · doi:10.1007/978-1-4939-3530-7_8 · Cited by 24 · see citing works

BioID: A Method to Generate a History of Protein Associations

May, D. G., & Roux, K. J. (2019) · Methods in molecular biology · doi:10.1007/978-1-4939-9537-0_7 · Cited by 22 · see citing works

APEX2 Proximity Proteomics Resolves Flagellum Subdomains and Identifies Flagellum Tip-Specific Proteins in Trypanosoma brucei

Vélez‐Ramírez, D. E., Shimogawa, M. M., Ray, S. S., Lopez, A., Rayatpisheh, S., Langousis, G., Gallagher-Jones, M., Dean, S., Wohlschlegel, J. A., & Hill, K. L. (2021) · mSphere · doi:10.1128/msphere.01090-20 · Cited by 21 · see citing works

Identification and characterisation of a Theileria annulata proline-rich microtubule and SH3 domain-interacting protein (TaMISHIP) that forms a complex with CLASP1, EB1, and CD2AP at the schizont surface

Huber, S., Karagenç, T., Ritler, D., Rottenberg, S., & Woods, K. L. (2018) · Cellular Microbiology · doi:10.1111/cmi.12838 · Cited by 21 · see citing works

Basal Body Protein TbSAF1 Is Required for Microtubule Quartet Anchorage to the Basal Bodies in Trypanosoma brucei

Dong, X., Lim, T. K., Lin, Q., & He, C. Y. (2020) · mBio · doi:10.1128/mbio.00668-20 · Cited by 20 · see citing works

The Trypanosome Flagellar Pocket Collar and Its Ring Forming Protein—TbBILBO1

Perdomo, D., Bonhivers, M., & Robinson, D. R. (2016) · Cells · doi:10.3390/cells5010009 · Cited by 20 · see citing works

Structures of three MORN repeat proteins and a re-evaluation of the proposed lipid-binding properties of MORN repeats

Sajko, S., Grishkovskaya, I., Košťan, J., Graewert, M. A., Setiawan, K., Truebestein, L., Niedermüller, K., Gehin, C. J. C., Sponga, A., Puchinger, M. G., et al. (2020) · PLoS ONE · doi:10.1371/journal.pone.0242677 · Cited by 19 · see citing works

Chemical proteomics for a comprehensive understanding of functional activity and the interactome

Kozoriz, K., & Lee, J. (2025) · Chemical Society Reviews · doi:10.1039/d5cs00381d · Cited by 18 · see citing works

Maintenance of hook complex integrity and centrin arm assembly facilitates flagellum inheritance in Trypanosoma brucei

Pham, K. T. M., Hu, H., & Li, Z. (2020) · Journal of Biological Chemistry · doi:10.1074/jbc.ra120.014237 · Cited by 18 · see citing works

Characterization of RBP9 and RBP10, two developmentally regulated RNA-binding proteins in Trypanosoma brucei

Pablos, L. M. D., Kelly, S. L., Nascimento, J. D. F., Sunter, J. D., & Carrington, M. (2017) · Open Biology · doi:10.1098/rsob.160159 · Cited by 18 · see citing works

A comparison of three approaches for the discovery of novel tripartite attachment complex proteins in Trypanosoma brucei

Baudouin, H. C. M., Pfeiffer, L., & Ochsenreiter, T. (2020) · PLoS neglected tropical diseases · doi:10.1371/journal.pntd.0008568 · Cited by 17 · see citing works

A cytoskeletal protein complex is essential for division of intracellular amastigotes of Leishmania mexicana

Kelly, F. D., Tran, K. D., Hatfield, J., Schmidt, K., Sánchez, M. A., & Landfear, S. M. (2020) · Journal of Biological Chemistry · doi:10.1074/jbc.ra120.014065 · Cited by 16 · see citing works

Role for the flagellum attachment zone in Leishmania anterior cell tip morphogenesis

Halliday, C., Yanase, R., Catta‐Preta, C. M. C., Moreira-Leite, F. F., Myšková, J., Pružinová, K., Volf, P., Mottram, J. C., & Sunter, J. D. (2020) · PLoS Pathogens · doi:10.1371/journal.ppat.1008494 · Cited by 16 · see citing works

A unified approach towards Trypanosoma brucei functional genomics using Gibson assembly

McAllaster, M. R., Sinclair, A. N., Hilton, N. A., & de Graffenried, C. L. (2016) · Molecular and Biochemical Parasitology · doi:10.1016/j.molbiopara.2016.08.001 · Cited by 15 · see citing works

Spatial proteomics reveal that the protein phosphatase PTP1B interacts with and may modify tyrosine phosphorylation of the rhomboid protease RHBDL4

Ikeda, K. N., & Freeman, M. (2019) · Journal of Biological Chemistry · doi:10.1074/jbc.ra118.007074 · Cited by 15 · see citing works

In situ structural analysis of the flagellum attachment zone in Trypanosoma brucei using cryo-scanning transmission electron tomography

Trépout, S. (2020) · Journal of Structural Biology X · doi:10.1016/j.yjsbx.2020.100033 · Cited by 15 · see citing works

TbSmee1 regulates hook complex morphology and the rate of flagellar pocket uptake in Trypanosoma brucei

Perry, J. A., Sinclair, A. N., McAllaster, M. R., & de Graffenried, C. L. (2017) · Molecular Microbiology · doi:10.1111/mmi.13885 · Cited by 14 · see citing works

Split-BioID — Proteomic Analysis of Context-specific Protein Complexes in Their Native Cellular Environment

Schopp, I. M., & Béthune, J. (2018) · Journal of Visualized Experiments · doi:10.3791/57479 · Cited by 12 · see citing works

AEE788 Inhibits Basal Body Assembly and Blocks DNA Replication in the African Trypanosome

Sullenberger, C., Piqué, D. G., Ogata, Y., & Mensa‐Wilmot, K. (2017) · Molecular Pharmacology · doi:10.1124/mol.116.106906 · Cited by 12 · see citing works

An orphan kinesin in Trypanosoma brucei regulates hook complex assembly and Golgi biogenesis

Zhou, Q., KURASAWA, Y., Hu, H., Onofre, T. S., & Li, Z. (2024) · mBio · doi:10.1128/mbio.02634-24 · Cited by 10 · see citing works

Identifying Protein‐Protein Interactions by Proximity Biotinylation with AirID and splitAirID

Schaack, G. A., Sullivan, O. M., & Mehle, A. (2023) · Current Protocols · doi:10.1002/cpz1.702 · Cited by 10 · see citing works

A DOT1B/Ribonuclease H2 Protein Complex Is Involved in R-Loop Processing, Genomic Integrity, and Antigenic Variation in Trypanosoma brucei

Eisenhuth, N., Vellmer, T., Rauh, E. T., Butter, F., & Janzen, C. J. (2021) · mBio · doi:10.1128/mbio.01352-21 · Cited by 10 · see citing works

ZapE/Afg1 interacts with Oxa1 and its depletion causes a multifaceted phenotype

Pyrih, J., Rašková, V., Škodová‐Sveráková, I., Pánek, T., & Lukeš, J. (2020) · PLoS ONE · doi:10.1371/journal.pone.0234918 · Cited by 9 · see citing works

The bi-lobe-associated LRRP1 regulates Ran activity in Trypanosoma brucei

Bayat, S., Brasseur, A., Chua, X. L., Zhang, Y., Zhou, Q., Low, B. C., & He, C. Y. (2014) · Journal of Cell Science · doi:10.1242/jcs.148015 · Cited by 9 · see citing works

Paving the Way: Contributions of Big Data to Apicomplexan and Kinetoplastid Research

Kent, R. S., Briggs, E. M., Colon, B. L., Álvarez, C., Pereira, S. S., & Niz, M. D. (2022) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2022.900878 · Cited by 8 · see citing works

Microbial Pathogenesis in the Era of Spatial Omics

Lempke, S. L., May, D., & Ewald, S. E. (2023) · Infection and Immunity · doi:10.1128/iai.00442-22 · Cited by 8 · see citing works

The unusual flagellar-targeting mechanism and functions of the trypanosome ortholog of the ciliary GTPase Arl13b

Zhang, Y., Huang, Y., Srivathsan, A., Lim, T. K., Lin, Q., & He, C. Y. (2018) · Journal of Cell Science · doi:10.1242/jcs.219071 · Cited by 8 · see citing works

Tag Thy Neighbour: Nanometre-Scale Insights Into Kinetoplastid Parasites With Proximity Dependent Biotinylation

Geoghegan, V., Mottram, J. C., & Jones, N. G. (2022) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2022.894213 · Cited by 7 · see citing works

Basic Biology of Trypanosoma brucei with Reference to the Development of Chemotherapies

Dean, S. (2021) · Current Pharmaceutical Design · doi:10.2174/1381612827666210119105008 · Cited by 7 · see citing works

Proximity labeling approaches to study protein complexes during virus infection

Belinchón, F. J. Z., Carriquí-Madroñal, B., & Gerold, G. (2021) · Advances in virus research · doi:10.1016/bs.aivir.2021.02.001 · Cited by 7 · see citing works

Proximity Labeling of the Chlamydia trachomatis Inclusion Membrane

Olson, M. G., Jorgenson, L. M., Widner, R. E., & Rucks, E. A. (2019) · Methods in molecular biology · doi:10.1007/978-1-4939-9694-0_17 · Cited by 7 · see citing works

Novel Cytoskeleton-Associated Proteins in Trypanosoma brucei Are Essential for Cell Morphogenesis and Cytokinesis

Schock, M., Schmidt, S., & Ersfeld, K. (2021) · Microorganisms · doi:10.3390/microorganisms9112234 · Cited by 7 · see citing works

Bhalin, an Essential Cytoskeleton-Associated Protein of Trypanosoma brucei Linking TbBILBO1 of the Flagellar Pocket Collar with the Hook Complex

Reix, C. E. B., Florimond, C., Cayrel, A., Mailhé, A., Agnero-Rigot, C., Landrein, N., Dacheux, D., Havlicek, K., Bonhivers, M., Morriswood, B., et al. (2021) · Microorganisms · doi:10.3390/microorganisms9112334 · Cited by 7 · see citing works

RNA editing catalytic complexes edit multiple mRNA sites non-processively in Trypanosoma brucei

Carnes, J., McDermott, S. M., & Stuart, K. D. (2023) · Molecular and Biochemical Parasitology · doi:10.1016/j.molbiopara.2023.111596 · Cited by 6 · see citing works

Intrabody-Induced Cell Death by Targeting the T. brucei Cytoskeletal Protein Tb BILBO1

Reix, C. E. B., Ramanantsalama, M. R., Primo, C. D., Minder, L., Bonhivers, M., Dacheux, D., & Robinson, D. R. (2021) · Microbiology Spectrum · doi:10.1128/spectrum.00915-21 · Cited by 6 · see citing works

Context-Specific and Proximity-Dependent Labeling for the Proteomic Analysis of Spatiotemporally Defined Protein Complexes with Split-BioID

Ramirez, C. C. A., Egetemaier, S., & Béthune, J. (2020) · Methods in molecular biology · doi:10.1007/978-1-0716-1126-5_17 · Cited by 6 · see citing works

Identification of interacting proteins using proximity-dependent biotinylation with BioID2 in Trypanosoma brucei v1Preprint

Pyrih, J., & Lukeš, J. (2020) · doi:10.17504/protocols.io.bdrri556

Anti-cytoskeleton Immunoscreening of Trypanosoma brucei Expression Library Reveals Novel Immunogenic Conserved Putative Proteins

Magyezi, B. G., Okalang, U., Musisi, K., Mwijjwiga, W. E., & Lubega George, W. (2019) · Journal of Advances in Biology & Biotechnology · doi:10.9734/jabb/2019/v22i130104 · Cited by 1 · see citing works

Mapping Trypanosoma Protein Interactome by Proximity-Dependent Biotinylation

Krishna, C. K., Erdmann, R., & Kalel, V. C. (2026) · Methods in molecular biology · doi:10.1007/978-1-0716-5142-1_18

Integrative approaches to investigate the architecture and assembly of BILBO1, a multidomain cytoskeletal protein from Trypanosoma brucei

Dong, G. (2015) · Biological Systems Open Access

Proteomics and theTrypanosoma bruceicytoskeleton: advances and opportunities

Portman, N., & Gull, K. (2012) · Parasitology · doi:10.1017/s0031182012000443 · Cited by 12 · see citing works