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Functional Expression of hMYH, a Human Homolog of the Escherichia coli MutY Protein
Open accessAbstract
We have previously described the hMYH cDNA and genomic clones (M. M. Slupska et al., J. Bacteriol. 178:3885–3892, 1996). Here, we report that the enzyme expressed from an hMYH cDNA clone in Escherichia coli complements the mutator phenotype in a mutY mutant and can remove A from an A · 8-hydroxydeoxyguanine mismatch and to a lesser extent can remove A from an A · G mismatch in vitro.
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Cites
Insertion of specific bases during DNA synthesis past the oxidation-damaged base 8-oxodG
Shibutani, S., Takeshita, M., & Grollman, A. P. (1991) · Nature · doi:10.1038/349431a0 · Cited by 2,224
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Metadata
- Authors
- Slupska, M. M., Luther, W. M., Chiang, J.-H., Yang, H., & Miller, J. H.
- Venue
- Journal of Bacteriology
- Publisher
- American Society for Microbiology
- Published
- 1999-10
- Volume
- 181
- Issue
- 19
- Pages
- 6210-6213
- ISSN
- 0021-9193 (ISSN-L)
- 1098-5530
- OpenAlex
- W2171741556
- Cited by
- 174
- References
- 1
- FWCI
- 2.50
- Type
- journal article
- Language
- en
- Open access
- green
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- Slupska, M. M., Luther, W. M., Chiang, J.-H., Yang, H., & Miller, J. H. (1999). Functional Expression of hMYH, a Human Homolog of the Escherichia coli MutY Protein. Journal of Bacteriology. https://doi.org/10.1128/jb.181.19.6210-6213.1999
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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