The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Matrix-Assisted Laser Desorption Ionization–Time of Flight Mass Spectrometry as an Alternative to 16S rRNA Gene Sequencing for Identification of Difficult-To-Identify Bacterial Strains
Open accessAbstract
Conventional methods are sometimes insufficient to identify human bacterial pathogens, and alternative techniques, often molecular, are required. Matrix-assisted laser desorption ionization–time of flight mass spectrometry (MALDI-TOF MS) identified with a valid score 45.9% of 410 clinical isolates from 207 different difficult-to-identify species having required 16S rRNA gene sequencing. MALDI-TOF MS might represent an alternative to 16S rRNA gene sequencing.
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Cites
Seng, P., Drancourt, M., Gouriet, F., La Scola, B., Fournier, P., Rolain, J. M., & Raoult, D. (2009) · Clinical Infectious Diseases · doi:10.1086/600885 · Cited by 1,983 · cited 3×
“For routine isolates, MALDI-TOF MS has shown overall correct identification levels often greater than 85% (1, 3, 8, 15, 17).”
BackgroundMethodSalminen, M. K., Rautelin, H., Tynkkynen, S., Poussa, T., Saxelin, M., Valtonen, V., & Jarvinen, A. (2006) · Clinical Infectious Diseases · doi:10.1086/500214 · Cited by 218
Cited by
MALDI-TOF mass spectrometry: an emerging technology for microbial identification and diagnosis
Singhal, N., Kumar, M., Kanaujia, P. K., & Virdi, J. S. (2015) · Frontiers in Microbiology · doi:10.3389/fmicb.2015.00791 · Cited by 1,605
Seng, P., Abat, C., Rolain, J. M., Colson, P., Lagier, J.-C., Gouriet, F., Fournier, P. E., Drancourt, M., La Scola, B., & Raoult, D. (2013) · Journal of Clinical Microbiology · doi:10.1128/jcm.00492-13 · Cited by 438
Tan, K. E., Ellis, B. C., Lee, R., Stamper, P. D., Zhang, S. X., & Carroll, K. C. (2012) · Journal of Clinical Microbiology · doi:10.1128/jcm.01405-12 · Cited by 326
Pre-trained Maldi Transformers improve MALDI-TOF MS-based prediction
(2025) · doi:10.1016/j.compbiomed.2025.109695 · Cited by 17
Identification and differentiation of avian Mycoplasma species using MALDI-TOF MS
Baudler, L., Scheufen, S., Ziegler, L., Möller Palau-Ribes, F., Ewers, C., & Lierz, M. (2019) · Journal of Veterinary Diagnostic Investigation · doi:10.1177/1040638719856932 · Cited by 7
Metadata
- Authors
- Bizzini, A., Jaton, K., Romo, D., Bille, J., Prod'hom, G., & Greub, G.
- Venue
- Journal of Clinical Microbiology
- Publisher
- American Society for Microbiology
- Published
- 2011-02
- Volume
- 49
- Issue
- 2
- Pages
- 693-696
- ISSN
- 0095-1137 (ISSN-L)
- 1098-660X
- OpenAlex
- W2050083056
- Cited by
- 245
- References
- 2
- FWCI
- 10.49
- Type
- journal article
- Language
- en
- Open access
- green
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- CoChat. (2026). Citation check: Matrix-Assisted Laser Desorption Ionization–Time of Flight Mass Spectrometry as an Alternative to 16S rRNA Gene Sequencing for Identification of Difficult-To-Identify Bacterial Strains. https://app.cochat.ai/papers/10.1128/jcm.01463-10
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- Bizzini, A., Jaton, K., Romo, D., Bille, J., Prod'hom, G., & Greub, G. (2011). Matrix-Assisted Laser Desorption Ionization–Time of Flight Mass Spectrometry as an Alternative to 16S rRNA Gene Sequencing for Identification of Difficult-To-Identify Bacterial Strains. Journal of Clinical Microbiology. https://doi.org/10.1128/jcm.01463-10
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