Cited by 554Viral gastroenteritis research and epidemiologyBacterial Identification and Susceptibility TestingSalmonella and Campylobacter epidemiology

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Multicenter Evaluation of the BioFire FilmArray Gastrointestinal Panel for Etiologic Diagnosis of Infectious Gastroenteritis

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Buss, Sarah N., Leber, Amy, Chapin, Kimberle, Fey, Paul D., Bankowski, Matthew J., Jones, Matthew K., Rogatcheva, Margarita, Kanack, Kristen J., Bourzac, Kevin M.·2015·Journal of Clinical Microbiology

DOI 10.1128/jcm.02674-14PMC PMC4390666

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Abstract

The appropriate treatment and control of infectious gastroenteritis depend on the ability to rapidly detect the wide range of etiologic agents associated with the disease. Clinical laboratories currently utilize an array of different methodologies to test for bacterial, parasitic, and viral causes of gastroenteritis, a strategy that suffers from poor sensitivity, potentially long turnaround times, and complicated ordering practices and workflows. Additionally, there are limited or no testing methods routinely available for most diarrheagenic Escherichia coli strains, astroviruses, and sapoviruses. This study assessed the performance of the FilmArray Gastrointestinal (GI) Panel for the simultaneous detection of 22 different enteric pathogens directly from stool specimens: Campylobacter spp., Clostridium difficile (toxin A/B), Plesiomonas shigelloides , Salmonella spp., Vibrio spp., Vibrio cholerae , Yersinia enterocolitica , enteroaggregative E. coli , enteropathogenic E. coli , enterotoxigenic E. coli , Shiga-like toxin-producing E. coli ( stx 1 and stx 2 ) (including specific detection of E. coli O157), Shigella spp./enteroinvasive E. coli , Cryptosporidium spp., Cyclospora cayetanensis , Entamoeba histolytica , Giardia lamblia , adenovirus F 40/41, astrovirus, norovirus GI/GII, rotavirus A, and sapovirus. Prospectively collected stool specimens ( n = 1,556) were evaluated using the BioFire FilmArray GI Panel and tested with conventional stool culture and molecular methods for comparison. The FilmArray GI Panel sensitivity was 100% for 12/22 targets and ≥94.5% for an additional 7/22 targets. For the remaining three targets, sensitivity could not be calculated due to the low prevalences in this study. The FilmArray GI Panel specificity was ≥97.1% for all panel targets. The FilmArray GI Panel provides a comprehensive, rapid, and streamlined alternative to conventional methods for the etiologic diagnosis of infectious gastroenteritis in the laboratory setting. The potential advantages include improved performance parameters, a more extensive menu of pathogens, and a turnaround time of as short as 1 h.

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Background
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BackgroundSelf-citation
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Method
The incidence of laboratory-confirmed cases of enteric pathogens in Denmark 2018: a national observational study
Svendsen, A. T., Nielsen, H. L., Bytzer, P., Coia, J., Engberg, J., Holt, H. M., Lemming, L., Lomborg, S., Marmolin, E., Olesen, B., et al. (2023) · Infectious Diseases · doi:10.1080/23744235.2023.2183253 · Cited by 7
“Higher sensitivity of PCR compared to culture is well documented [30,31].”
Background
Identification and Evaluation of Cryptosporidium Species from New York City Cases of Cryptosporidiosis (2015 to 2018): a Watershed Perspective
Alderisio, K., Mergen, K., Moessner, H., & Madison-Antenucci, S. (2023) · Microbiology spectrum · doi:10.1128/spectrum.03921-22 · Cited by 7
A rapid multiplex real-time PCR detection of toxigenic Clostridioides difficile directly from fecal samples
Jia, X., Wang, Y.-Y., Zhang, W.-Z., Li, W.-G., Bai, L., Lu, J.-X., Ma, C.-Y., & Wu, Y. (2023) · 3 Biotech · doi:10.1007/s13205-022-03434-6 · Cited by 7
“However, the CCNA procedure is complicated, time-consuming, and limited by cell types and equipment (Buss et al. 2015).”
Method
Pathogen-Specific Alterations in the Gut Microbiota Predict Outcomes in Flare of Inflammatory Bowel Disease Complicated by Gastrointestinal Infection
Axelrad, J., Chen, Z., Devlin, J., Ruggles, K., & Cadwell, K. (2022) · Clinical and Translational Gastroenterology · doi:10.14309/ctg.0000000000000550 · Cited by 7
Acute Viral Gastrointestinal (GI) Infections in the Tropics—A Role for Cartridge-Based Multiplex PCR Panels?
Kramme, S., Dähne, T., Fomenko, A., & Panning, M. (2022) · Tropical Medicine and Infectious Disease · doi:10.3390/tropicalmed7050080 · Cited by 6
“Comparison studies of current syndromic panels have demonstrated equivalent or even superior performance to reference assays [45,48,49].”
Result
Intestinal and Extra-Intestinal Manifestations of Campylobacter in the Immunocompromised Host
Schiaffino, F., & Kosek, M. N. (2020) · Current treatment options in infectious diseases/Current treatment options in infectious disease · doi:10.1007/s40506-020-00243-4 · Cited by 8
Multi-organism gastrointestinal polymerase chain reaction positivity among pediatric transplant vs non-transplant populations: A single-center experience
Stone, J. M., Savage, A., Hudspeth, M., Twombley, K., Kasi, N., Quiros, J., Arbizu, R., & Curry, S. R. (2020) · Pediatric Transplantation · doi:10.1111/petr.13771 · Cited by 7
Use of the Multiplex Diagnostic PCR Panel in Diarrheal Disease: Expert Guidance on the Interpretation of Results With a Focus on Travelers' Diarrhea
Connor, B. A., Martin, G. J., & Riddle, M. S. (2020) · The American Journal of Gastroenterology · doi:10.14309/ajg.0000000000000735 · Cited by 5
Performance evaluation of gastrointestinal viral ELIte panel multiplex RT-PCR assay for the diagnosis of rotavirus, adenovirus and astrovirus infection.
Grazia, S. D., Bonura, F., Pepe, A., Muli, S., Cappa, V., Filizzolo, C., Mangiaracina, L., Urone, N., & Giammanco, G. (2019) · Journal of Virological Methods · doi:10.1016/j.jviromet.2019.03.010 · Cited by 7
Detection of Acute Gastroenteritis Agents By Molecular Methods
Göktas, S., Gökmen, A. A., & Şamlıoglu, P. (2018) · doi:10.5799/jcei.413060 · Cited by 7
“Farklı ticari multiplex PZR kitlerinin kullanıldığı üç farklı çalışmada koenfeksiyon oranı %14,2, %31,5, %33,5 olarak bulunmuştur [4,13-15].”
Diagnostics in a Forward Deployed Setting.
Swierczewski, B., & Simons, M. (2017) · Military Medicine · doi:10.7205/milmed-d-17-00069 · Cited by 7
Molecular Contamination and Amplification Product Inactivation
Sefers, S. E., & Schmitz, J. E. (2018) · Springer eBooks · doi:10.1007/978-3-319-33900-9_24 · Cited by 6
Kogene PowerChek Multiplex Real-time PCR Kits Versus the BioFire FilmArray Gastrointestinal Panel: Roles of Crossing Point Values and Melting Curves in Interpreting the FilmArray Gastrointestinal Panel
Yoo, I., Jo, S., Kwon, J., Han, J., Lee, H. K., & Park, Y.-J. (2025) · Annals of Laboratory Medicine · doi:10.3343/alm.2025.0047 · Cited by 6
“However, 20–36% false positive (FP) results were reported for norovirus with the FilmArray GI Panel [6–8].”
Multicenter evaluation of the QIAstat-Dx Gastrointestinal Panel 2, a multiplex PCR platform for the diagnosis of acute gastroenteritis
Szymczak, W. A., Engsbro, A. L., Lisby, J. G., González‐López, J. J., Granato, P. A., Ledeboer, N. A., Wolk, D. M., Young, S., Rhoads, D. D., Caspar, Y., et al. (2025) · Journal of Clinical Microbiology · doi:10.1128/jcm.01983-24 · Cited by 5
“For this investigation, 1,939 specimens prospectively collected from nine clinical sites in the United States and four clinical sites in Europe were evaluated (Table 1).”
Influential
Stool multiplex PCR assay versus conventional stool tests for detecting gastrointestinal infection as a cause for flare of inflammatory bowel disease
Kutar, M., Desai, D. C., Abraham, P., Gupta, T., & Dhoble, P. (2025) · Indian Journal of Gastroenterology · doi:10.1007/s12664-025-01773-9 · Cited by 6
“Stool multiplex molecular polymerase chain reaction (PCR) assay allows for simultaneous detection of nucleic acids from 22 bacteria, viruses and parasites from stool samples sent in Cary Blair transport medium [3].”
A Multimodal Intervention to Reduce C. difficile Infections and Stool Testing
Cotter, J. M., Stokes, C. L., Tong, S., Birkholz, M. C., Child, J., Cost, C. R., Coughlin, R. L., Cox, S., Dolan, S. A., Dorris, K. M. O., et al. (2024) · PEDIATRICS · doi:10.1542/peds.2023-061981 · Cited by 4
Clinical Impact of Multiplex Molecular Diagnostic Testing in Children With Acute Gastroenteritis Presenting to an Emergency Department: A Multicenter Prospective Study
Pavia, A. T., Cohen, D. M., Leber, A. L., Daly, J. A., Jackson, J. T., Selvarangan, R., Kanwar, N., Bender, J. M., Bard, J. D., Festekjian, A., et al. (2023) · Clinical Infectious Diseases · doi:10.1093/cid/ciad710 · Cited by 12
Self-citation
Comparison of two novel one-tube nested real-time qPCR assays to detect human-infecting Cyclospora spp.
Richins, T., Houghton, K., Barratt, J., Sapp, S., Peterson, A. C., & Qvarnstrom, Y. (2023) · Microbiology spectrum · doi:10.1128/spectrum.01388-23 · Cited by 6
“In the years after the BioFire FilmArray GI Panel (BioFire assay) became available for clinical use, the number of laboratory-confirmed cyclosporiasis cases has increased, owing at least in part to the use of this new diagnostic test; this phenomenon was especially pronounced during the 2018 cyclosporiasis peak period…”
Result
The limit of detection of the BioFire® FilmArray® gastrointestinal panel for the foodborne parasite Cyclospora cayetanensis
Peterson, A., Richins, T., Houghton, K., Mishina, M., Sharma, S. D., Sambhara, S., Jacobson, D. K., Qvarnstrom, Y., & Cama, V. (2023) · Diagnostic microbiology and infectious disease · doi:10.1016/j.diagmicrobio.2023.116030 · Cited by 6
“Candidatus Campylobacter infans” detection is not associated with diarrhea in children under the age of 2 in Peru
Bardales, P. F. G., Schiaffino, F., Huynh, S., Olórtegui, M. P., Yori, P. P., Vasquez, T. N. P., Villanueva, K. M., Huansi, G. E. C., López, W. V. S., Cooper, K. K., et al. (2022) · PLoS Neglected Tropical Diseases · doi:10.1371/journal.pntd.0010869 · Cited by 6
“This is partly a result of a larger proportion of cases diagnosed using nucleic acid-based techniques or ELISA, which is higher in low-income settings in comparison to high-income settings and in part secondary to limited capacity and funds to sequence genomes that are isolated in LMIC settings [4,5].”
Detección molecular de patógenos entéricos en niños con diarrea en un hospital centinela de vigilancia de rotavirus en Chile
Poulain, C., Héctor Galeno, A., Loayza, S., Vergara, N., Valdivieso, F. R., Coria, P., Sotomayor, V., Simian, M. E., Acevedo, J., & Farfán, M. J. (2021) · Revista chilena de infectología · doi:10.4067/s0716-10182021000100054 · Cited by 7
Evaluation of the Vibrant DNA microarray for the high-throughput multiplex detection of enteric pathogens in clinical samples
Yang, Y., Rajendran, V., Jayaraman, V., Wang, T., Bei, K., Krishna, K., Rajasekaran, K., Rajasekaran, J. J., & Krishnamurthy, H. K. (2019) · Gut Pathogens · doi:10.1186/s13099-019-0329-2 · Cited by 11
Clinical Evaluation and Cost Analysis of Great Basin Shiga Toxin Direct Molecular Assay for Detection of Shiga Toxin-Producing Escherichia coli in Diarrheal Stool Specimens
Faron, M., Ledeboer, N., Connolly, J., Granato, P., Alkins, B. R., Bard, J. D., Daly, J., Young, S., & Buchan, B. (2016) · Journal of Clinical Microbiology · doi:10.1128/jcm.01939-16 · Cited by 6
“than routine culture and EIA methods (7, 12, 15).”
Method
Use of multiplex PCR to rapidly diagnose febrile patients during a gastroenteritis outbreak among Ebola virus treatment unit workers
Evans, T. O., Fominyam, T., Matthews, S., Bailey, M., & Hutley, E. (2016) · Journal of the Royal Army Medical Corps · doi:10.1136/jramc-2016-000662 · Cited by 6
Gastrointestinal PCR panel results and antibiotic use in acute gastroenteritis cases: How appropriate are we in our usage?
Çetin, S., Telli, E., Şahin, A. M., Uğur, M., Aydın, E., Şenel, İ., & Yetkin, M. A. (2024) · Indian Journal of Medical Microbiology · doi:10.1016/j.ijmmb.2024.100536 · Cited by 3
A Point Source Gastroenteritis Outbreak in a High School Putatively Due to Clostridium perfringens: Timely Investigation Is Everything
Papanikou, S., Sideroglou, T., Chrysostomou, A., Kyritsi, M., Spaniolas, S., Bouboulis, D., Mouchtouri, V., & Mellou, K. (2023) · Foodborne pathogens and disease · doi:10.1089/fpd.2022.0057 · Cited by 5
“…, Plesiomonas shigelloides , Clostridium difﬁcile [Toxin A/B], Salmonella spp., Cryptosporidium spp., Cy-clospora cayetanensis , Entamoeba histolytica , Giardia lamblia , Adenovirus F40/41, Astrovirus, Norovirus GI/GII, Rotavirus A and Sapovirus [genogroups I, II, IV and V]) (Buss et al, 2015).”
Replacement of Culture with Molecular Testing for Diagnosis Infectious Diseases.
Capraro, G. A. (2022) · Clinics in Laboratory Medicine · doi:10.1016/j.cll.2022.09.010 · Cited by 5
Detection of Zoonotic Gastrointestinal Pathogens in Dairy Sheep and Goats by Using FilmArray® Multiplex-PCR Technology
Tsilipounidaki, K., Florou, Z., Lianou, D. T., Michael, C. K., Katsarou, E., Skoulakis, A., Fthenakis, G., & Petinaki, E. (2022) · Microorganisms · doi:10.3390/microorganisms10040714 · Cited by 5
“[7] evaluated the technology in a collection of 1556 faecal sam‐ ples, by comparing its findings against results obtained by conventional faecal cultures and molecular methods.”
BackgroundResult
Improving Care for Children with Bloody Diarrhea at Risk for Hemolytic Uremic Syndrome
Burns, C. S., Rubin, J., Sardesai, T., Klein, E. J., Vora, S. B., Kearney, R., & Rutman, L. (2022) · Pediatric Quality and Safety · doi:10.1097/pq9.0000000000000517 · Cited by 4
Diagnostic syndromic multiplex approaches for gastrointestinal infections
Maldonado-Garza, H. J., Garza‐González, E., Bocanegra‐Ibarias, P., & Flores-Treviño, S. (2021) · Expert Review of Gastroenterology & Hepatology · doi:10.1080/17474124.2021.1899807 · Cited by 4
Clostridioides difficile laboratory diagnostic techniques: a comparative approach of rapid and molecular methods
Camargo, T., Silva, M., Camargo, L. F., Biotto, V. P., Doi, A., Koga, P., França, C., & Martino, M. (2021) · Archives of Microbiology · doi:10.1007/s00203-020-02148-8 · Cited by 5
Performance characteristics of a quantitative PCR assay on repository stool specimens and smeared filter-paper cards
Tisdale, M. D., Mitra, I., Mccoy, A. J., Simons, M., Reynolds, N. D., Swierczewski, B., Liu, J., Houpt, E., Fraser, J. A., Riddle, M., et al. (2020) · BMC Research Notes · doi:10.1186/s13104-020-05340-7 · Cited by 5
Molecular and non-molecular approaches to etiologic diagnosis of gastroenteritis
Zhang, X., Das, S., Dunbar, S. A., & Tang, Y. (2020) · Advances in clinical chemistry · doi:10.1016/bs.acc.2020.02.007 · Cited by 7
Diagnostic Test Accuracy of Commercial Tests for Detection of Shiga Toxin–Producing Escherichia coli: A Systematic Review and Meta-Analysis
Tarr, G. A. M., Lin, C. Y., Vandermeer, B., Lorenzetti, D., Tarr, P. I., Chui, L., Hartling, L., & Freedman, S. B. (2020) · Clinical Chemistry · doi:10.1093/clinchem/hvz006 · Cited by 6
Performance of commercial tests for molecular detection of Shiga toxin-producing Escherichia coli (STEC): a systematic review and meta-analysis protocol
Tarr, G. A. M., Lin, C. Y., Lorenzetti, D., Chui, L., Tarr, P. I., Hartling, L., Vandermeer, B., & Freedman, S. B. (2019) · BMJ Open · doi:10.1136/bmjopen-2018-025950 · Cited by 6
Point-of-Care Diagnostics for Infectious Diseases: Present and Future
Kim, S., & Shin, J. (2018) · Korean Journal of Medicine · doi:10.3904/kjm.2018.93.2.181 · Cited by 5
Fulminant Haemophilus Influenzae Type a Infection in a 4-year-old with Previously Undiagnosed Asplenic Heterotaxy.
Headrick, A., Schmit, E., & Kimberlin, D. (2017) · The Pediatric Infectious Disease Journal · doi:10.1097/inf.0000000000001758 · Cited by 5
No Detection of Entamoeba Histolytica by Multiplex Polymerase Chain Reaction in Children With Acute Non-bloody Diarrhea in Guatemala
Kamidani, S., Melgar, M. A., Robinson, C., Asturias, E., Berman, S., & Gaensbauer, J. T. (2017) · The Pediatric Infectious Disease Journal · doi:10.1097/inf.0000000000001756 · Cited by 5
Evaluation of the Xpert Norovirus assay for the rapid detection of norovirus genogroups I and II in faecal specimens within a routine laboratory setting
Cleary, O., McNerney, R., Yandle, Z., & O'Sullivan, C. (2017) · British Journal of Biomedical Science · doi:10.1080/09674845.2017.1278886 · Cited by 5
Host Range of Cyclospora Species: Zoonotic Implication
Solarczyk, P. (2021) · Acta Protozoologica · doi:10.4467/16890027ap.21.002.14062 · Cited by 5
Comparative epidemiology of diarrhoeal organisms in high-risk adults using multiplex PCR gastrointestinal panel testing: a multicentre observational study
Shu, J. H., Wang, H., Misra, A., Rhoads, D. D., Nowacki, A. S., Dalton, J. E., & Deshpande, A. (2025) · Clinical Microbiology and Infection · doi:10.1016/j.cmi.2025.08.008 · Cited by 4
Prevalence of human adenovirus in children with acute gastroenteritis in the New Vaccine Surveillance Network (NVSN) from 2016 to 2019.
Kinzler, A., Wikswo, M. E., Balasubramani, G., D'Agostino, H., Sax, T. M., Dauer, K., Weinberg, G. A., Szilyagi, P., Sahni, L. C., Boom, J., et al. (2025) · Journal of Clinical Virology · doi:10.1016/j.jcv.2025.105822 · Cited by 4
Enteropathogenic Escherichia coli (EPEC) Causes Chronic Diarrhea and Hyponatremia in an Adult
Chen, S., & Feuille, C. (2025) · Clinical Case Reports · doi:10.1002/ccr3.70288 · Cited by 4
“For example, the BioFire Film Array Gastrointestinal Panel (GIP) (BioFire Diagnostics, Salt Lake City, UT) offers a multiplex PCR assay that screens diarrheal samples for 22 enteric pathogens [2].”
Influential
Factors Associated With Actionable Gastrointestinal Panel Results in Hospitalized Children
Ho, E. C., Cotter, J. M., Thomas, J. F., Birkholz, M. C., & Dominguez, S. R. (2023) · Hospital Pediatrics · doi:10.1542/hpeds.2023-007273 · Cited by 3
Successful management of life-threatening post-COVID-19 cryptosporidiosis in a renal transplant patient: a case report
Shrateh, O. N., Jobran, A. W. M., Zaid, M. A., & Saleh, M. (2023) · The Pan African Medical Journal · doi:10.11604/pamj.2023.45.10.39548 · Cited by 4
“Additionally, analyses point to the possibility that transplant recipients may experience prolonged viral shedding after infection, which could result in PCR tests having better sensitivity than it would in the general population.”
MethodInfluential
Evaluation of viral co-infections among patients with community-associated Clostridioides difficile infection
Korhonen, L., Cohen, J. A., Gregoricus, N., Farley, M., Perlmutter, R., Holzbauer, S., Dumyati, G., Beldavs, Z., Paulick, A. L., Vinjé, J., et al. (2020) · PLoS ONE · doi:10.1371/journal.pone.0240549 · Cited by 4
“However, one of these studies had a small sample of only seven CDI cases [10], limiting its generalizability, and three other studies included children <2 years of age [5, 9, 11], who can have high prevalence of C.”
Background
Are CMV-predictive scores in inflammatory bowel disease useful in clinical practice?
Störkmann, H., Rödel, J., Stallmach, A., & Reuken, P. (2020) · Zeitschrift für Gastroenterologie - German Journal of Gastroenterology · doi:10.1055/a-1221-5463 · Cited by 4
“When combining these tests with rapid multiplex-PCR to rule out gastrointestinal infections, the first decision whether a patient requires anti-infective or immunosuppressive therapy can be made within several hours [13].”
Method
Development of a Mobile Laboratory for Sudden Onset Disasters
Marr, I., Francis, J., Stephens, D., Marshall, K., Read, D. J., Baird, R., & Coatsworth, N. (2020) · Disaster Medicine and Public Health Preparedness · doi:10.1017/dmp.2019.128 · Cited by 4
Description of Enteropathic Escherichia coli Species in Pediatric Patients at a Quaternary Children's Hospital.
Nycz, B., Pretty, K., Gomez-Trujillo, A., Sanchez, B., & Dominguez, S. (2019) · Journal of the Pediatric Infectious Diseases Society · doi:10.1093/jpids/piz081 · Cited by 4
Shiga-Like Toxin-Producing Escherichia coli Inducing Diarrhea in Patients with Multiple Myeloma Diagnosed by BioFire PCR-Film Array
Kreiniz, N., Abu-Ahmad, A., Golan-Shany, O., Paz, A., & Tadmor, T. (2019) · Acta Haematologica · doi:10.1159/000498906 · Cited by 4

Authors: Buss, S. N., Leber, A., Chapin, K., Fey, P. D., Bankowski, M. J., Jones, M. K., Rogatcheva, M., Kanack, K. J., & Bourzac, K. M.
Affiliations: University of Nebraska Medical Center (US)
Nationwide Children's Hospital (US)
Lifespan (US)
University of Hawaiʻi at Mānoa (US)
BioFire Diagnostics (United States) (US)
ORCID: Buss, Sarah N.
Leber, Amy
Chapin, Kimberle
Fey, Paul D.
Jones, Matthew K.
Venue: Journal of Clinical Microbiology
Publisher: American Society for Microbiology
Published: 2015-03
Volume: 53
Issue: 3
Pages: 915-925
ISSN: 0095-1137 (ISSN-L)
1098-660X
DOI: 10.1128/jcm.02674-14
PMC: PMC4390666
OpenAlex: W2169792847
Cited by: 554
References: 0
Citations by year: 2026: 43 · 2025: 46 · 2024: 42 · 2023: 62 · 2022: 43 · 2021: 51 · 2020: 61 · 2019: 41 · 2018: 58 · 2017: 48 · 2016: 39 · 2015: 18
FWCI: 42.22
Type: journal article
Language: en
Open access: green
www.ncbi.nlm.nih.gov
Licence: journals.asm.org/non-commercial-tdm-license (tdm)
Locations: Journal of Clinical Microbiology (publishedVersion)
PubMed Central (publishedVersion)
PubMed (publishedVersion)
Funders: BioFire Diagnostics
National Institutes of Health
National Institute of Allergy and Infectious Diseases (R01AI104593, R01AI089489)
Topics: Health Sciences › Medicine › Infectious Diseases › Viral gastroenteritis research and epidemiology
Health Sciences › Medicine › Microbiology (medical) › Bacterial Identification and Susceptibility Testing
Life Sciences › Agricultural and Biological Sciences › Food Science › Salmonella and Campylobacter epidemiology
Keywords: infectious gastroenteritis, enteric pathogens, multiplex PCR, sensitivity and specificity, diarrheagenic Escherichia coli, norovirus, rotavirus, sapovirus, Cryptosporidium, Giardia lamblia, Shiga toxin-producing Escherichia coli, rapid molecular diagnostics
MeSH terms: Adolescent, Adult, Aged, Aged, 80 and over, Animals, Bacteria, Child, Child, Preschool, Feces, Female, Gastroenteritis, Humans, Infant, Infant, Newborn, Male, Microbiological Techniques, Middle Aged, Parasites, Prospective Studies, Sensitivity and Specificity, Time Factors, Viruses, Molecular Diagnostic Techniques, Young Adult

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Multicenter Evaluation of the BioFire FilmArray Gastrointestinal Panel for Etiologic Diagnosis of Infectious Gastroenteritis

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