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Direct agglutination test for diagnosis of Toxoplasma infection: method for increasing sensitivity and specificity
Open accessAbstract
A method that increases the sensitivity and specificity of the direct agglutination (AG) test for diagnosis of Toxoplasma gondii infection is described. Qualitative results in the Sabin-Feldman dye test (DT) and AG test were in excellent agreement (98%). Differences in titers between these two tests often related to the length of time the individual was infected. The AG test titer was most often lower than the DT titer during acute (recent) infection; the AG test titer was most often higher than the DT titer in older or chronic infection. If the AG test antigen described here can be made available, the AG test would be ideal for use as a screening test and would provide a simple and inexpensive means for the surveillance of seronegative women during pregnancy and for detection of seroconversions.
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Cited by
Sources and Reservoirs of Toxoplasma gondii Infection on 47 Swine Farms in Illinois
Dubey, J. P., Weigel, R. M., Siegel, A. M., Thulliez, P., Kitron, U. D., Mitchell, M. A., Mannelli, A., Mateus-Pinilla, N. E., Shen, S. K., Kwok, O. C. H., et al. (1995) · The Journal of Parasitology · doi:10.2307/3283961 · Cited by 260
Long-Term Antibody Responses of Cats Fed Toxoplasma gondii Tissue Cysts
Dubey, J. P., Lappin, M. R., & Thulliez, P. (1995) · The Journal of Parasitology · doi:10.2307/3284035 · Cited by 134
Serological survey of Toxoplasma gondii infection in domestic cats from northeastern Portugal
Lopes, A. P., Cardoso, L., & Rodrigues, M. (2008) · Veterinary Parasitology · doi:10.1016/j.vetpar.2008.05.007 · Cited by 86
Metadata
- Authors
- Desmonts, G., & Remington, J. S.
- Venue
- Journal of Clinical Microbiology
- Publisher
- American Society for Microbiology
- Published
- 1980-06
- Volume
- 11
- Issue
- 6
- Pages
- 562-568
- ISSN
- 0095-1137 (ISSN-L)
- 1098-660X
- OpenAlex
- W1662893264
- Cited by
- 583
- References
- 0
- FWCI
- 4.82
- Type
- journal article
- Language
- en
- Open access
- green
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- Desmonts, G., & Remington, J. S. (1980). Direct agglutination test for diagnosis of Toxoplasma infection: method for increasing sensitivity and specificity. Journal of Clinical Microbiology. https://doi.org/10.1128/jcm.11.6.562-568.1980
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