The DOI matches its Crossref record; 24 of the 24 references it cites were found in a registry or an index.
Comparison of various repetitive DNA elements as genetic markers for strain differentiation and epidemiology of Mycobacterium tuberculosis
Open accessAbstract
Five different genetic elements have been found to be associated with genetic rearrangements in Mycobacterium tuberculosis complex strains. Of these elements, the insertion sequence IS6110 is presently the most frequently used genetic marker for strain differentiation of M. tuberculosis. In the present study we compared five genetic elements for their potentials to differentiate a given cluster of M. tuberculosis strains. Because of the presence of only a single copy of IS6110 or two IS6110 copies at the same chromosomal locus, a large number of strains could not be differentiated by IS6110 fingerprinting. Most strains, including the low-copy-number IS6110 strains, could be differentiated by fingerprinting with the 36-bp direct repeat or the polymorphic GC-rich repetitive DNA element. Less discriminative power was obtained with the major polymorphic tandem repeat and the insertion element IS1081. One strain which did not contain IS6110 DNA was encountered. Until now, this element has invariantly been found to be present in all M. tuberculosis complex strains. On the basis of classical taxonomic criteria and sequencing of the 16S rRNA gene, this strain was shown to be a genuine M. tuberculosis strain. Therefore, the use of this element as a target for polymerase chain reaction-facilitated detection of M. tuberculosis should be reconsidered.
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Self-citationEdlin, B. R., Tokars, J. I., Grieco, M. H., Crawford, J. T., Williams, J., Sordillo, E. M., Ong, K. R., Kilburn, J. O., Dooley, S. W., Castro, K. G., et al. (1992) · New England Journal of Medicine · doi:10.1056/nejm199206043262302 · Cited by 861
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Towards a Phylogeny and Definition of Species at the Molecular Level within the Genus Mycobacterium
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Self-citationFischl, M. A., Uttamchandani, R. B., Daikos, G. L., Poblete, R. B., Moreno, J. N., Reyes, R. R., Boota, A. M., Thompson, L. M., Cleary, T. J., & Lai, S. (1992) · Annals of Internal Medicine · doi:10.7326/0003-4819-117-3-177 · Cited by 371
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Lino, C. A., Harper, J. C., Carney, J. P., & Timlin, J. A. (2018) · Drug Delivery · doi:10.1080/10717544.2018.1474964 · Cited by 1,185
Short-sequence DNA repeats in prokaryotic genomes
van Belkum, A., Scherer, S., van Alphen, L., & Verbrugh, H. (1998) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.62.2.275-293.1998 · Cited by 737
Predominance of a single genotype of Mycobacterium tuberculosis in countries of east Asia
van Soolingen, D., Qian, L., de Haas, P. E., Douglas, J. T., Traore, H., Portaels, F., Qing, H. Z., Enkhsaikan, D., Nymadawa, P., & van Embden, J. D. (1995) · Journal of Clinical Microbiology · doi:10.1128/jcm.33.12.3234-3238.1995 · Cited by 706
Self-citationKremer, K., van Soolingen, D., Frothingham, R., Haas, W. H., Hermans, P. W. M., Martín, C., Palittapongarnpim, P., Plikaytis, B. B., Riley, L. W., Yakrus, M. A., et al. (1999) · Journal of Clinical Microbiology · doi:10.1128/jcm.37.8.2607-2618.1999 · Cited by 579
Self-citationControl and prevention of tuberculosis in the United Kingdom: Code of Practice 2000
Joint Tuberculosis Committee of the British Thoracic Society (2000) · Thorax · doi:10.1136/thorax.55.11.887 · Cited by 366
Metadata
- Authors
- van Soolingen, D., de Haas, P. E., Hermans, P. W., Groenen, P. M., & van Embden, J. D.
- Venue
- Journal of Clinical Microbiology
- Publisher
- American Society for Microbiology
- Published
- 1993-08
- Volume
- 31
- Issue
- 8
- Pages
- 1987-1995
- ISSN
- 0095-1137 (ISSN-L)
- 1098-660X
- OpenAlex
- W1884882993
- Cited by
- 489
- References
- 24
- FWCI
- 20.04
- Type
- journal article
- Language
- en
- Open access
- green
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- van Soolingen, D., de Haas, P. E., Hermans, P. W., Groenen, P. M., & van Embden, J. D. (1993). Comparison of various repetitive DNA elements as genetic markers for strain differentiation and epidemiology of Mycobacterium tuberculosis. Journal of Clinical Microbiology. https://doi.org/10.1128/jcm.31.8.1987-1995.1993
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