The DOI matches its Crossref record; 36 of the 36 references it cites were found in a registry or an index.
A segment of the 5' nontranslated region of encephalomyocarditis virus RNA directs internal entry of ribosomes during in vitro translation
Open accessAbstract
Picornavirus RNAs are uncapped messengers and have unusually long 5' nontranslated regions (5'NTRs) which contain many noninitiating AUG triplets. The translational efficiency of different picornavirus RNAs varies between different cell-free extracts and even in the same extract, such as micrococcal nuclease-treated rabbit reticulocyte lysates. The effect of the poliovirus 5'NTR on in vitro translation was compared with that of the 5'NTR of encephalomyocarditis virus by the use of synthetic mRNAs, micrococcal nuclease-treated HeLa cell extracts, and rabbit reticulocyte lysates. Artificial mono- and dicistronic mRNAs synthesized with T7 RNA polymerase were used to investigate whether the 5'NTR of encephalomyocarditis virus RNA contains a potential internal ribosomal entry site. The sequence between nucleotides 260 and 484 in the 5'NTR of encephalomyocarditis RNA was found to play a critical role in the efficient translation in both mono- and dicistronic mRNAs. Our data suggest that an internal ribosomal entry site resides in this region.
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Cites
Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4
LAEMMLI, U. K. (1970) · Nature · doi:10.1038/227680a0 · Cited by 249,961
Molecular Cloning: A Laboratory Manual
Sambrook, J., Fritsch, E., & Maniatis, T. (1989) · UCLA - Biblioteca de Ciencias de la Salud · Cited by 133,589
Raza, H., John, A., & Nemmar, A. (2013) · Cellular Physiology and Biochemistry · doi:10.1159/000350087 · Cited by 47,221
Kozak, M. (1986) · Cell · doi:10.1016/0092-8674(86)90762-2 · Cited by 4,741
Kozak, M. (1981) · Nucleic Acids Research · doi:10.1093/nar/9.20.5233 · Cited by 1,242
Primary structure, gene organization and polypeptide expression of poliovirus RNA
Kitamura, N., Semler, B. L., Rothberg, P. G., Larsen, G. R., Adler, C. J., Dorner, A. J., Emini, E. A., Hanecak, R., Lee, J. J., van der Werf, S., et al. (1981) · Nature · doi:10.1038/291547a0 · Cited by 914
Self-citationHow do eucaryotic ribosomes select initiation regions in messenger RNA?
Kozak, M. (1978) · Cell · doi:10.1016/0092-8674(78)90039-9 · Cited by 815
Etchison, D., Milburn, S. C., Edery, I., Sonenberg, N., & Hershey, J. W. (1982) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)33352-0 · Cited by 583
Jackson, R. J., & Hunt, T. (1983) · Methods in Enzymology · doi:10.1016/s0076-6879(83)96008-1 · Cited by 551
5'-terminal cap structure in eucaryotic messenger ribonucleic acids
Banerjee, A. K. (1980) · Microbiological Reviews · doi:10.1128/mmbr.44.2.175-205.1980 · Cited by 531
Cited by
Regulation of mRNA Translation and Stability by microRNAs
Fabian, M. R., Sonenberg, N., & Filipowicz, W. (2010) · Annual Review of Biochemistry · doi:10.1146/annurev-biochem-060308-103103 · Cited by 3,214
eIF4 Initiation Factors: Effectors of mRNA Recruitment to Ribosomes and Regulators of Translation
Gingras, A.-C., Raught, B., & Sonenberg, N. (1999) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.68.1.913 · Cited by 2,121
Translational control in stress and apoptosis
Holcik, M., & Sonenberg, N. (2005) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm1618 · Cited by 1,366
Internal ribosome entry sites in eukaryotic mRNA molecules
Hellen, C. U. T., & Sarnow, P. (2001) · Genes & Development · doi:10.1101/gad.891101 · Cited by 986
Cello, J., Paul, A. V., & Wimmer, E. (2002) · Science · doi:10.1126/science.1072266 · Cited by 980
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Metadata
- Authors
- Jang, S. K., Kräusslich, H. G., Nicklin, M. J., Duke, G. M., Palmenberg, A. C., & Wimmer, E.
- Venue
- Journal of Virology
- Publisher
- American Society for Microbiology
- Published
- 1988-08
- Volume
- 62
- Issue
- 8
- Pages
- 2636-2643
- ISSN
- 0022-538X (ISSN-L)
- 1098-5514
- OpenAlex
- W1807212217
- Cited by
- 1,362
- References
- 36
- FWCI
- 10.80
- Type
- journal article
- Language
- en
- Open access
- green
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- Jang, S. K., Kräusslich, H. G., Nicklin, M. J., Duke, G. M., Palmenberg, A. C., & Wimmer, E. (1988). A segment of the 5' nontranslated region of encephalomyocarditis virus RNA directs internal entry of ribosomes during in vitro translation. Journal of Virology. https://doi.org/10.1128/jvi.62.8.2636-2643.1988
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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