The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Canonical Eukaryotic Initiation Factors Determine Initiation of Translation by Internal Ribosomal Entry
Open accessAbstract
Translation of picornavirus RNA is initiated after ribosomal binding to an internal ribosomal entry site (IRES) within the 5' untranslated region. We have reconstituted IRES-mediated initiation on encephalomyocarditis virus RNA from purified components and used primer extension analysis to confirm the fidelity of 48S preinitiation complex formation. Eukaryotic initiation factor 2 (eIF2), eIF3, and eIF4F were required for initiation; eIF4B and to a lesser extent the pyrimidine tract-binding protein stimulated this process. We show that eIF4F binds to the IRES in a novel cap-independent manner and suggest that cap- and IRES-dependent initiation mechanisms utilize different modes of interaction with this factor to promote ribosomal attachment to mRNA.
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Duke, G. M., Hoffman, M. A., & Palmenberg, A. C. (1992) · Journal of Virology · doi:10.1128/jvi.66.3.1602-1609.1992 · Cited by 234
Kozak, M. (1994) · Journal of Molecular Biology · doi:10.1016/s0022-2836(05)80019-1 · Cited by 101
Cited by
The mechanism of eukaryotic translation initiation and principles of its regulation
Jackson, R. J., Hellen, C. U. T., & Pestova, T. V. (2010) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2838 · Cited by 2,759
Self-citationeIF4 Initiation Factors: Effectors of mRNA Recruitment to Ribosomes and Regulators of Translation
Gingras, A.-C., Raught, B., & Sonenberg, N. (1999) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.68.1.913 · Cited by 2,121
Initiation of translation in prokaryotes and eukaryotes
Kozak, M. (1999) · Gene · doi:10.1016/s0378-1119(99)00210-3 · Cited by 1,364
Switch from translation to RNA replication in a positive-stranded RNA virus
Gamarnik, A. V., & Andino, R. (1998) · Genes & Development · doi:10.1101/gad.12.15.2293 · Cited by 508
Yang, H.-S., Jansen, A. P., Komar, A. A., Zheng, X., Merrick, W. C., Costes, S., Lockett, S. J., Sonenberg, N., & Colburn, N. H. (2003) · Molecular and Cellular Biology · doi:10.1128/mcb.23.1.26-37.2003 · Cited by 494
Metadata
- Authors
- Pestova, T. V., Hellen, C. U. T., & Shatsky, I. N.
- Venue
- Molecular and Cellular Biology
- Publisher
- Informa UK Limited
- Published
- 1996-12
- Volume
- 16
- Issue
- 12
- Pages
- 6859-6869
- ISSN
- 0270-7306 (ISSN-L)
- 1098-5549
- OpenAlex
- W1920555941
- Cited by
- 491
- References
- 2
- FWCI
- 6.93
- Type
- journal article
- Language
- en
- Open access
- green
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- Pestova, T. V., Hellen, C. U. T., & Shatsky, I. N. (1996). Canonical Eukaryotic Initiation Factors Determine Initiation of Translation by Internal Ribosomal Entry. Molecular and Cellular Biology. https://doi.org/10.1128/mcb.16.12.6859
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
